Names | |
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Preferred IUPAC name 2-Hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dione | |
Identifiers | |
3D model (JSmol) | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.001.421 |
EC Number |
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PubChem CID | |
UNII | |
CompTox Dashboard (EPA) | |
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Properties | |
C15H14O3 | |
Molar mass | 242.27 |
Appearance | Yellow crystals |
Melting point | 140 °C (284 °F; 413 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). |
Lapachol is a natural phenolic compound isolated from the bark of the lapacho tree. [3] This tree is known botanically as Handroanthus impetiginosus , but was formerly known by various other botanical names such as Tabebuia avellanedae. [4] Lapachol is also found in other species of Handroanthus.
Lapachol is usually encountered as a yellow, skin-irritating powder from wood. Chemically, it is a derivative of vitamin K. [5]
Once studied as a possible treatment for some types of cancer, it is now considered too toxic for use. [6] [7] [8] [9]
§Hooker-Oxidation§
Tabebuia is a genus of flowering plants in the family Bignoniaceae. Tabebuia consists almost entirely of trees, but a few are often large shrubs. A few species produce timber, but the genus is mostly known for those that are cultivated as flowering trees.
Soman is an extremely toxic chemical substance. It is a nerve agent, interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase. It is an inhibitor of both acetylcholinesterase and butyrylcholinesterase. As a chemical weapon, it is classified as a weapon of mass destruction by the United Nations according to UN Resolution 687. Its production is strictly controlled, and stockpiling is outlawed by the Chemical Weapons Convention of 1993 where it is classified as a Schedule 1 substance. Soman was the third of the so-called G-series nerve agents to be discovered along with GA (tabun), GB (sarin), and GF (cyclosarin).
Cypermethrin (CP) is a synthetic pyrethroid used as an insecticide in large-scale commercial agricultural applications as well as in consumer products for domestic purposes. It behaves as a fast-acting neurotoxin in insects. It is easily degraded on soil and plants but can be effective for weeks when applied to indoor inert surfaces. It is a non-systemic and non-volatile insecticide that acts by contact and ingestion, used in agriculture and in pest control products. Exposure to sunlight, water and oxygen will accelerate its decomposition. Cypermethrin is highly toxic to fish, bees and aquatic insects, according to the National Pesticides Telecommunications Network (NPTN). It is found in many household ant and cockroach killers, including Raid, Ortho, Combat, ant chalk, and some products of Baygon in Southeast Asia.
Bignoniaceae is a family of flowering plants in the order Lamiales commonly known as the bignonias or trumpet vines. It is not known to which of the other families in the order it is most closely related.
Tea tree oil, also known as melaleuca oil, is an essential oil with a fresh, camphoraceous odor and a colour that ranges from pale yellow to nearly colourless and clear. It is derived from the leaves of the tea tree, Melaleuca alternifolia, native to southeast Queensland and the northeast coast of New South Wales, Australia. The oil comprises many constituent chemicals, and its composition changes if it is exposed to air and oxidizes. Commercial use of tea tree oil began in the 1920s, pioneered by the entrepreneur Arthur Penfold.
Lithium orotate (C5H3LiN2O4) is a salt of orotic acid and lithium. It is available as the monohydrate, LiC5H3N2O4·H2O. In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium ions. It is marketed as a dietary supplement, though it has been researched minimally between 1973–1986 to treat certain medical conditions, such as alcoholism and Alzheimer's disease.
Malathion is an organophosphate insecticide which acts as an acetylcholinesterase inhibitor. In the USSR, it was known as carbophos, in New Zealand and Australia as maldison and in South Africa as mercaptothion.
Nefiracetam is a nootropic drug of the racetam family. Preliminary research suggests that it may possess certain antidementia properties in rats.
Diisopropyl fluorophosphate (DFP) or Isoflurophate is an oily, colorless liquid with the chemical formula C6H14FO3P. It is used in medicine and as an organophosphorus insecticide. It is stable, but undergoes hydrolysis when subjected to moisture.
Toluene toxicity refers to the harmful effects caused by toluene on the body.
Lapacho or taheebo is herbal tea made from the inner bark of the pau d'arco tree Handroanthus impetiginosus.
Handroanthus impetiginosus, the pink ipê, pink lapacho or pink trumpet tree, is a tree in the family Bignoniaceae, distributed throughout North, Central and South America, from northern Mexico south to northern Argentina. Along with all the other species in the Handroanthus genus, it is the national tree of Paraguay.
Handroanthus chrysotrichus, synonym Tabebuia chrysotricha, commonly known as the golden trumpet tree, is a semi-evergreen/semi-deciduous tree from Brazil. It is very similar to and often confused with Tabebuia ochracea. In Portuguese it is called ipê amarelo and its flower is considered the national flower of Brazil.
Tabebuia rosea, also called pink poui, and rosy trumpet tree is a neotropical tree that grows up to 30 m (98 ft) and can reach a diameter at breast height of up to 100 cm (3 ft). The Spanish name roble de sabana, meaning "savannah oak", is widely used in Costa Rica, probably because it often remains in heavily deforested areas and because of the resemblance of its wood to that of oak trees. It is the national tree of El Salvador, where it is called "Maquilíshuat".
Triamiphos (chemical formula: C12H19N6OP) is an organophosphate used as a pesticide and fungicide. It is used to control powdery mildews on apples and ornamentals. It was discontinued by the US manufacturer in 1998.
Handroanthus is a genus of flowering plants in the family Bignoniaceae. It consists of 30 species of trees, known in Latin America by the common names poui, pau d'arco, or ipê. The latter sometimes appears as epay or simply ipe (unaccented) in English. The large timber species are sometimes called lapacho or guayacan, but these names are more properly applied to the species Handroanthus lapacho and Handroanthus guayacan, respectively.
Roseodendron is a genus of flowering plants in the family Bignoniaceae. It consists of two species, Roseodendron donnell-smithii and Roseodendron chryseum. The type species for the genus is R. donnell-smithii. Both species are cultivated as ornamentals for their numerous, large, yellow flowers.
25E-NBOMe is a derivative of the phenethylamine 2C-E. It acts in a similar manner to related compounds such as 25I-NBOMe, which are potent agonists at the 5-HT2A receptor. 25E-NBOMe has been sold as a drug and produces similar effects in humans to related compounds such as 25I-NBOMe and 25C-NBOMe.
Handroanthus heptaphyllus, commonly referred to as the pink trumpet tree or pink tab, is a Bignoniaceae tree native to tropical and subtropical regions of South America. It grows in the high forest watershed of the Paraná River, Paraguay River and Uruguay River. It has a limited distribution, almost exclusively inhabiting low lands with wet and deep soils, where it forms part of the upper layer of tree cover.
4-Methylcathinone, is a stimulant drug of the cathinone chemical class. It is a metabolite of the better known drug mephedrone (4-methylmethcathinone).