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Harvey Mudd College (HMC) is a private liberal arts college in Claremont, California, focused on science and engineering. It is part of the Claremont Colleges, which share adjoining campus grounds and resources. The college enrolled 902 undergraduate students as of 2021 and awards the Bachelor of Science degree. Admission to Harvey Mudd is highly competitive, and the college maintains a competitive academic culture.
Maria Goeppert Mayer was a German-born American theoretical physicist, and Nobel laureate in Physics for proposing the nuclear shell model of the atomic nucleus. She was the second woman to win a Nobel Prize in physics, the first being Marie Curie. In 1986, the Maria Goeppert-Mayer Award for early-career women physicists was established in her honor.
Cancer immunotherapy (immuno-oncotherapy) is the stimulation of the immune system to treat cancer, improving the immune system's natural ability to fight the disease. It is an application of the fundamental research of cancer immunology and a growing subspecialty of oncology.
An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions to help destroy the remaining tumour. Oncolytic viruses are thought not only to cause direct destruction of the tumour cells, but also to stimulate host anti-tumour immune system responses. Oncolytic viruses also have the ability to affect the tumor micro-environment in multiple ways.
Virotherapy is a treatment using biotechnology to convert viruses into therapeutic agents by reprogramming viruses to treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral immunotherapy. These branches use three different types of treatment methods: gene overexpression, gene knockout, and suicide gene delivery. Gene overexpression adds genetic sequences that compensate for low to zero levels of needed gene expression. Gene knockout uses RNA methods to silence or reduce expression of disease-causing genes. Suicide gene delivery introduces genetic sequences that induce an apoptotic response in cells, usually to kill cancerous growths. In a slightly different context, virotherapy can also refer more broadly to the use of viruses to treat certain medical conditions by killing pathogens.
Ellen S. Vitetta is the director of the Cancer Immunobiology Center at the University of Texas Southwestern Medical Center in Dallas.
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Trachette Levon Jackson is an American mathematician who is a professor of mathematics at the University of Michigan and is known for work in mathematical oncology. She uses many different approaches, including continuous and discrete mathematical models, numerical simulations, and experiments to study tumor growth and treatment. Specifically, her lab is interested in "molecular pathways associated with intratumoral angiogenesis," "cell-tissue interactions associated with tumor-induced angiogenesis," and "tumor heterogeneity and cancer stem cells."
Weiqing Gu is a Chinese-American mathematician who works as the Avery Professor of Mathematics and director of the mathematics clinic at Harvey Mudd College. Her research concerns differential geometry and Grassmann manifolds. She has also worked with Harvey Mudd colleague Lisette de Pillis on the mathematical modeling of cancer.
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Elizabeth M. Jaffee is an American oncologist specializing in pancreatic cancer and immunotherapy.
Talithia D. Williams is an American statistician and mathematician at Harvey Mudd College who researches the spatiotemporal structure of data. She was the first black woman to achieve tenure at Harvey Mudd College. Williams is an advocate for engaging more African Americans in engineering and science.
Rachel Levy is an American mathematician and blogger. She currently serves as the inaugural Executive Director of the North Carolina State University Data Science Academy. She was a 2020-21 AAAS Science and Technology Policy Fellow, serving in the United States Senate and sponsored by the American Mathematical Society. From 2018-2020 she served as deputy executive director of the Mathematical Association of America(2018-2020). As a faculty member at Harvey Mudd College from 2007-2019 her research was in applied mathematics, including the mathematical modeling of thin films, and the applications of fluid mechanics to biology. This work was funded by The National Science Foundation, Research Corporation, Howard Hughes Medical Institute, and US Office of Naval Research.
Susan Elizabeth Martonosi is an American mathematician who works at Harvey Mudd College as the Joseph B. Platt Professor of Mathematics and as the director of the Global Clinic Program at Harvey Mudd. Her research studies operations research, game theory, social networks, and their applications to counter-terrorism, epidemiology, and sports analytics.
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References
- ↑ Mathematics Faculty at HMC, archived from the original on 2017-06-06, retrieved 2015-09-04.
- ↑ The Harvey Mudd College Center for Quantitative Life Sciences , retrieved 2015-09-04.
- ↑ Lisette de Pillis at the Mathematics Genealogy Project
- ↑ Sipics, Michelle (October 18, 2009), "Mathematics Meets Oncology and Immunology", SIAM News .
- ↑ Professor Lisette de Pillis (HMC) named Goeppert-Mayer Argonne Distinguished Scholar, April 1999, retrieved 2015-09-04.
- ↑ 2016 Class of the Fellows of the AMS, American Mathematical Society , retrieved 2015-11-16.
