These are the Official Charts Company's UK Independent Singles Chart number-one singles of 2022.
| Chart date (week ending) | Song | Artist(s) | Record label | References |
|---|---|---|---|---|
| 6 January | "Merry Xmas Everybody" | Slade | BMG | [1] |
| 13 January | "Down Under" | Luude featuring Colin Hay | Sweat It Out | [2] |
| 20 January | "Fingers Crossed" | Lauren Spencer-Smith | Lauren Spencer-Smith | [3] |
| 27 January | [4] | |||
| 3 February | [5] | |||
| 10 February | "Down Under" | Luude featuring Colin Hay | Sweat It Out | [6] |
| 17 February | "Fingers Crossed" | Lauren Spencer-Smith | Lauren Spencer-Smith | [7] |
| 24 February | "Khabib" | Central Cee | Central Cee | [8] |
| 3 March | "Used to This" | Wilkinson and Issey Cross | BMG/Sleepless Music | [9] |
| 10 March [b] | "Straight Back to It" | Central Cee | Central Cee | [10] |
| 17 March | "Reggae & Calypso" | Russ Millions with Buni and YV | One Of A Kind Music | [11] |
| 24 March | [12] | |||
| 31 March | [13] | |||
| 7 April | [14] | |||
| 14 April | [15] | |||
| 21 April | [16] | |||
| 28 April | [17] | |||
| 5 May | [18] | |||
| 12 May | [19] | |||
| 19 May | [20] | |||
| 26 May | [21] | |||
| 2 June | "Charmer" | N-Dubz | Xploded Music | [22] |
| 9 June | "Prince Andrew Is a Sweaty Nonce" | The Kunts | Radical Rudeness | [23] |
| 16 June | "Balling" | Vibe Chemistry | D&B Allstars | [24] |
| 23 June | [25] | |||
| 30 June | [26] | |||
| 7 July | [27] | |||
| 14 July | "Someone Like You" | Adele | XL | [28] |
| 21 July | "Part of the Band" | The 1975 | Dirty Hit | [29] |
| 28 July | "Snap" | Rosa Linn | Nvak Collective | [30] |
| 4 August | "Doja" | Central Cee | Central Cee | [31] |
| 11 August | [32] | |||
| 18 August | [33] | |||
| 25 August | [34] | |||
| 1 September | [35] | |||
| 8 September | [36] | |||
| 15 September | [37] | |||
| 22 September | [38] | |||
| 29 September | [39] | |||
| 6 October | [40] | |||
| 13 October | [41] | |||
| 20 October | [42] | |||
| 27 October | "One Up" | [43] | ||
| 3 November [b] | "Body Paint" | Arctic Monkeys | Domino | [44] |
| 10 November | "Doja" | Central Cee | Central Cee | [45] |
| 17 November | [46] | |||
| 24 November | "Out of Nowhere" | Bugzy Malone and TeeDee | BSomebody | [47] |
| 1 December | [48] | |||
| 8 December | "Escapism" | Raye featuring 070 Shake | Human Re Sources | [49] |
| 15 December | [50] | |||
| 22 December | [51] | |||
| 29 December [a] | "Food Aid" | LadBaby | BMG | [52] |
| Position | Artist | Weeks at number one |
|---|---|---|
| 1 | Central Cee | 17 |
| 2 | Russ Millions | 11 |
| 2 | Buni | 11 |
| 2 | YV | 11 |
| 3 | Lauren Spencer-Smith | 4 |
| 3 | Vibe Chemistry | 4 |
| 3 | Raye | 3 |
| 3 | 070 Shake (as featuring) | 3 |
| 4 | Luude | 2 |
| 4 | Bugzy Malone | 2 |
| 4 | TeeDee | 2 |
| 4 | Colin Hay (as featuring) | 2 |
| 5 | Slade | 1 |
| 5 | Wilkinson | 1 |
| 5 | Issey Cross | 1 |
| 5 | N-Dubz | 1 |
| 5 | The Kunts | 1 |
| 5 | Adele | 1 |
| 5 | The 1975 | 1 |
| 5 | Rosa Linn | 1 |
| 5 | Arctic Monkeys | 1 |