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This list of important publications in medicine, is organized by field.
Some reasons why a particular publication might be regarded as important:
The definitive bibliographic source of books and articles demonstrating the history of medicine and identifying the first publications in the field is "Garrison and Morton". (Morton, Leslie T. (Leslie Thomas), Morton's medical bibliography : an annotated check-list of texts illustrating the history of medicine (Garrison and Morton). -- 5th ed. / edited by Jeremy M. Norman. -- Aldershot, Hants, England ; Brookfield, Vt., USA : Scolar Press, Gower, c1991. xxiv, 1243 p. ISBN 978-0-85967-897-1.) It is also available electronically, for a fee.
De Materia Medica
The Canon of Medicine
Exercitatio Anatomica de Motu Cordis et Sanguinis in Animalibus
The Principles and Practice of Medicine: Designed for the Use of Practitioners and Students of Medicine
Mortality in relation to smoking: 50 years' observation on male British doctors
Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study
Heart Protection Study
Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction
Pancreatic extracts in the treatment of diabetes mellitus
Diabetes mellitus: its differentiation into insulin-sensitive and insulin-insensitive types.