The most popular Latin pop songs in 2000, ranked by radio airplay audience impressions and measured by Nielsen BDS.
| Issue date | Song | Artist(s) | Ref. |
|---|---|---|---|
| January 1 | "Desnuda" | Ricardo Arjona | [1] |
| January 8 | [2] | ||
| January 15 | [3] | ||
| January 22 | [4] | ||
| January 29 | [5] | ||
| February 5 | [6] | ||
| February 12 | [7] | ||
| February 19 | [8] | ||
| February 26 | [9] | ||
| March 4 | [10] | ||
| March 11 | [11] | ||
| March 18 | [12] | ||
| March 25 | "Donde Está el Amor" | Charlie Zaa | [13] |
| April 1 | [14] | ||
| April 8 | "A Puro Dolor" | Son by Four | [15] |
| April 15 | [16] | ||
| April 22 | [17] | ||
| April 29 | [18] | ||
| May 6 | [19] | ||
| May 13 | [20] | ||
| May 20 | [21] | ||
| May 27 | [22] | ||
| June 3 | [23] | ||
| June 10 | "No Me Dejes de Querer" | Gloria Estefan | [24] |
| June 17 | "Entre el mar y una estrella" | Thalía | [25] |
| June 24 | "A Puro Dolor" | Son by Four | [26] |
| July 01 | [27] | ||
| July 8 | "Entre el mar y una estrella" | Thalía | [28] |
| July 15 | [29] | ||
| July 22 | "A Puro Dolor" | Son by Four | [30] |
| July 29 | [31] | ||
| August 5 | [32] | ||
| August 12 | "Júrame" | Gisselle | [33] |
| August 19 | "A Puro Dolor" | Son by Four | [34] |
| August 26 | [35] | ||
| September 2 | [36] | ||
| September 9 | [37] | ||
| September 16 | [38] | ||
| September 23 | "Cuando" | Ricardo Arjona | [39] |
| September 30 | [40] | ||
| October 7 | [41] | ||
| October 14 | [42] | ||
| October 21 | [43] | ||
| October 28 | [44] | ||
| November 4 | [45] | ||
| November 11 | "Yo te Amo" | Chayanne | [46] |
| November 18 | [47] | ||
| November 25 | [48] | ||
| December 2 | [49] | ||
| December 9 | [50] | ||
| December 16 | [51] | ||
| December 23 | [52] | ||
| December 30 | [53] | ||
