Mannheimia glucosida

Last updated

Mannheimia glucosida
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Bacteria
Kingdom: Pseudomonadati
Phylum: Pseudomonadota
Class: Gammaproteobacteria
Order: Pasteurellales
Family: Pasteurellaceae
Genus: Mannheimia
Species:
M. glucosida
Binomial name
Mannheimia glucosida
Angen et al. 1999 [1]
Type strain
CCUG 38457T; CIP 106063T; DSM 19638T; P925

Mannheimia glucosida is a species of Gram-negative bacteria in the family Pasteurellaceae. It was first described in 1999 following a taxonomic revision of the Pasteurella haemolytica complex. [1]

Contents

Etymology

The species name glucosida is derived from the Greek word glykys meaning "sweet" and the Latin suffix -ida, indicating a connection to glucosides. The name reflects the bacterium’s ability to ferment glucoside sugars. [2]

Morphology and physiology

M. glucosida is a non-motile, Gram-negative coccobacillus. It is facultatively anaerobic and forms small, grayish, smooth colonies on blood agar, often exhibiting β-hemolysis. The bacterium grows optimally at 37°C and can ferment glucose, lactose, maltose, and sucrose without gas production. It is oxidase-positive and catalase-positive. [3]

Isolation and habitat

The type strain was isolated from the lung of a sheep. Other strains have been recovered from the upper respiratory tracts of healthy ruminants, especially sheep and cattle, indicating a role as part of the commensal microbiota. [1]

Clinical significance

M. glucosida has been implicated in ovine mastitis. A 2010 study in southeastern Australia found it in 50% of clinical mastitis cases, while it was rarely found in healthy udder samples. [4]

Although primarily a veterinary organism, M. glucosida has also been isolated from a human bite wound, suggesting its potential as a zoonotic pathogen. [5]

Molecular identification

Molecular diagnostic methods such as PCR and 16S rRNA gene sequencing are used to identify M. glucosida. A 2015 study validated a multiplex PCR assay that differentiates among closely related Pasteurellaceae species, including M. glucosida, based on capsule loci and other genetic markers. [5]

References

  1. 1 2 3 Angen, O.; Mutters, R.; Caugant, D.A.; Olsen, J.E.; Bisgaard, M. (1999). "Taxonomic relationships of the [Pasteurella] haemolytica complex as evaluated by DNA–DNA hybridizations and 16S rRNA sequencing with proposal of Mannheimia haemolytica gen. nov., comb. nov., Mannheimia granulomatis comb. nov., Mannheimia glucosida sp. nov., Mannheimia ruminalis sp. nov. and Mannheimia varigena sp. nov". International Journal of Systematic Bacteriology. 49 (1): 67–86. doi:10.1099/00207713-49-1-67. PMID   10028248.
  2. "Species: Mannheimia glucosida". List of Prokaryotic names with Standing in Nomenclature (LPSN). DSMZ. Retrieved 2025-06-06.
  3. "Mannheimia glucosida B558, P925". BacDive – The Bacterial Diversity Metadatabase. Retrieved 2025-06-06.
  4. Omaleki, L.; Barber, S.R.; Allen, J.L.; Browning, G.F. (2010). "Mannheimia Species Associated with Ovine Mastitis". Journal of Clinical Microbiology. 48 (9): 3419–3422. doi:10.1128/JCM.01145-10. PMC   2937744 . PMID   20631198.
  5. 1 2 Howell, K.J.; Peters, S.E.; Wang, J.; Hernandez-Garcia, J.; Weinert, L.A.; Luan, S.L.; Wren, B.W. (2015). "Development of a multiplex PCR assay for rapid molecular serotyping of Haemophilus (Glaesserella) parasuis". Journal of Clinical Microbiology. 53 (12): 3812–3821. doi:10.1128/JCM.01249-15. PMC   4572521 . PMID   26202121.