Mel Rosenberg

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Mel Rosenberg
Prof. Mel Rosenberg.jpg
Born (1951-11-12) November 12, 1951 (age 72)
Nationality Flag of Israel.svg Israeli, Flag of Canada (Pantone).svg Canadian
Education B.Sc., Hebrew University of Jerusalem
M.S., Tel Aviv University
Ph.D., Tel Aviv University
Occupation Microbiologist
Employer Tel Aviv University
Title Professor
SpouseShulamit Sapir-Nevo
ChildrenAssif Rosenberg-Nevo
Adar Rosenberg-Nevo
Website https://www.melrosenberg.sites.tau.ac.il/

Mel Rosenberg (born Melvin Rosenberg, 12 November 1951 in Winnipeg, Manitoba, Canada) is a Canadian microbiologist best known for his research on the diagnosis and treatment of bad breath (halitosis). [1] [2]

Contents

Early life and education

Mel Rosenberg (Hebrew: מל רוזנברג) was born in Winnipeg, Manitoba, Canada in 1951. He grew up in Ottawa and immigrated to Israel in 1969. He received his Bachelor of Science from Hebrew University (1973) and went on to pursue both his Masters of Science (1975) and Ph.D. (1982) at Tel Aviv University. [2]

Academic professional

Rosenberg performed his Ph.D. research in the field of petroleum microbiology, under the supervision of Eugene Rosenberg and David Gutnick. His first publication as a graduate student, on the adhesion of microorganisms to oil droplets (1980), [3] became the most highly cited publication of FEMS Microbiology Journal and a "Citation Classic" by the Science Citation Index of 1991. [3] [4]

After receiving his doctorate in microbiology, Rosenberg held various faculty academic positions at the Sackler Faculty of Medicine and Goldschleger School of Dental Medicine at Tel Aviv University, and has received honorary appointments at the University of Rochester, University of Pennsylvania, University College London (Eastman Dental Hospital) and University of Toronto. [1]

Rosenberg's interest in the diagnosis and treatment of bad breath (halitosis) began in the mid-1980s. [2] [5] Research conducted in his laboratory at Tel Aviv University led to the development of two-phase mouthwashes, [6] now popular in the UK (under the name Dentyl Dual Action [7] ), in the US (under the name Colgate Total Advanced Health Mouthwash) and elsewhere. He is also the inventor or co-inventor of several other patents, including two microbial inoculation tools, the Quadloop [8] and the Diaslide, [9] an upside-down spray for treatment of shoe odor, [10] a deodorant for use in the shower, [11] and an anti-microbial flavor combination (Breathanol). [12] Rosenberg's research also led to the application of the Halimeter, [13] a volatile sulfide monitor, as an adjunct apparatus for the measurement of oral malodor. Rosenberg has edited several professional textbooks on bad breath and has written several reviews on the subject, notably "The Science of Bad Breath", published in Scientific American in 2002. [14] Together with Anton Amann, he served as Editor-in-Chief of the Journal of Breath Research , published by the Institute of Physics, from its inception until 2013. [5] [15]

In addition to his academic teaching activities, Dr. Rosenberg has been active in public education through the TED organization, including speaking in three TEDx events, co-organizing the TEDxShenkarCollege events, [16] and writing three animated lessons for TED-Ed, on bad breath, [17] dental caries [18] and body odor. [19] His TED-ED video on bad breath has been viewed more than 5 million times.

Mel Rosenberg pursues parallel careers as a jazz singer and musician, [20] and author of children's books. He is co-founder of Ourboox, a platform for online publishing of digital picture books. [21] [22] He appeared in a small role in the film JeruZalem in 2015. [23] At the end of 2021 Mel became the founding host of the "New Books in Children's Literature channel" on the New Books Network. .

Selected publications

Related Research Articles

<span class="mw-page-title-main">Mouthwash</span> Liquid rinse for oral hygiene

Mouthwash, mouth rinse, oral rinse, or mouth bath is a liquid which is held in the mouth passively or swirled around the mouth by contraction of the perioral muscles and/or movement of the head, and may be gargled, where the head is tilted back and the liquid bubbled at the back of the mouth.

<span class="mw-page-title-main">Listerine</span> Brand of mouthwash

Listerine is a brand of antiseptic mouthwash that is promoted with the slogan "Kills germs that cause bad breath". Named after Joseph Lister, who pioneered antiseptic surgery at the Glasgow Royal Infirmary in Scotland, Listerine was developed in 1879 by Joseph Lawrence, a chemist in St. Louis, Missouri.

<span class="mw-page-title-main">Bad breath</span> Presence of unpleasant odors in exhaled breath

Bad breath, also known as halitosis, is a symptom in which a noticeably unpleasant breath odour is present. It can result in anxiety among those affected. It is also associated with depression and symptoms of obsessive compulsive disorder.

Breath spray is a product sprayed into the mouth for the purpose of temporarily eliminating or at least covering up bad breath. The masking effect is short-term and reported to last for 4-6 hours. Breath sprays are occasionally advertised as being for smokers or those who dip tobacco, and occasionally to cover up the smell of cigarette/cigar smoking. Common flavours include cinnamon, spearmint and peppermint, as well as company-specific flavors, such as "Ice Mint", "Cool Mint" or "Supermint".

<i>Streptococcus mutans</i> Species of bacterium

Streptococcus mutans is a facultatively anaerobic, gram-positive coccus commonly found in the human oral cavity and is a significant contributor to tooth decay. It is part of the "streptococci", an informal general name for all species in the genus Streptococcus. The microbe was first described by James Kilian Clarke in 1924.

<span class="mw-page-title-main">Dimethyl sulfide</span> Chemical compound

Dimethyl sulfide (DMS) or methylthiomethane is an organosulfur compound with the formula (CH3)2S. The simplest thioether, it is a flammable liquid that boils at 37 °C (99 °F) and has a characteristic disagreeable odor. It is a component of the smell produced from cooking of certain vegetables, notably maize, cabbage, beetroot, and seafoods. It is also an indication of bacterial contamination in malt production and brewing. It is a breakdown product of dimethylsulfoniopropionate (DMSP), and is also produced by the bacterial metabolism of methanethiol.

Dental plaque is a biofilm of microorganisms that grows on surfaces within the mouth. It is a sticky colorless deposit at first, but when it forms tartar, it is often brown or pale yellow. It is commonly found between the teeth, on the front of teeth, behind teeth, on chewing surfaces, along the gumline (supragingival), or below the gumline cervical margins (subgingival). Dental plaque is also known as microbial plaque, oral biofilm, dental biofilm, dental plaque biofilm or bacterial plaque biofilm. Bacterial plaque is one of the major causes for dental decay and gum disease.

Black hairy tongue syndrome (BHT) is a condition of the tongue in which the small bumps on the tongue elongate with black or brown discoloration, giving a black and hairy appearance. The appearance may be alarming, but it is a harmless condition. Predisposing factors include smoking, xerostomia, soft diet, poor oral hygiene and certain medications. Management is facilitated by improving oral hygiene, especially scraping or brushing the tongue.

<span class="mw-page-title-main">Cetylpyridinium chloride</span> Chemical compound

Cetylpyridinium chloride (CPC) is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. It is an antiseptic that kills bacteria and other microorganisms. It has been shown to be effective in preventing dental plaque and reducing gingivitis. It has also been used as an ingredient in certain pesticides. Though one study seems to indicate cetylpyridinium chloride does not cause brown tooth stains, at least one mouthwash containing CPC as an active ingredient bears the warning label "In some cases, antimicrobial rinses may cause surface staining to teeth," following a failed class-action lawsuit brought by customers whose teeth were stained.

Olfactory reference syndrome (ORS) is a psychiatric condition in which there is a persistent false belief and preoccupation with the idea of emitting abnormal body odors which the patient thinks are foul and offensive to other individuals. People with this condition often misinterpret others' behaviors, e.g. sniffing, touching their nose or opening a window, as being referential to an unpleasant body odor which in reality is non-existent and cannot be detected by other people.

<span class="mw-page-title-main">Tooth brushing</span> Act of scrubbing teeth with a toothbrush

Tooth brushing is the act of scrubbing teeth with a toothbrush equipped with toothpaste. Interdental cleaning can be useful with tooth brushing, and together these two activities are the primary means of cleaning teeth, one of the main aspects of oral hygiene. The recommended amount of time for tooth brushing is two minutes.

A Halimeter is an instrument for measurement of the level of volatile sulfur compounds (VSCs) in the mouth.

<span class="mw-page-title-main">Oral hygiene</span> Cleaning the mouth by brushing the teeth and cleaning in between the teeth

Oral hygiene is the practice of keeping one's oral cavity clean and free of disease and other problems by regular brushing of the teeth and adopting good hygiene habits. It is important that oral hygiene be carried out on a regular basis to enable prevention of dental disease and bad breath. The most common types of dental disease are tooth decay and gum diseases, including gingivitis, and periodontitis.

<span class="mw-page-title-main">Tongue cleaner</span> Oral hygiene device

A tongue cleaner is an oral hygiene device designed to clean the coating on the upper surface of the tongue. While there is tentative benefit from the use of a tongue cleaner it is insufficient to draw clear conclusions regarding bad breath.

<span class="mw-page-title-main">Dentyl pH</span> Brand of mouthwash

Dentyl Dual Action, previously known as Dentyl Active, and originally as Dentyl pH, is a brand of mouthwash, an oral hygiene product designed to reduce the presence of bacteria responsible for tooth decay, gingivitis and halitosis. Traditional mouthwash formulations typically use alcohol or other antimicrobial ingredients to kill bacteria.

The BANA test is used to determine the proteolytic activity of certain oral anaerobes that contribute to oral malodor. Some bacteria, e.g. Prophyromona gingivalis, Treponema denticola, and Bacteroides forsythus produce waste products that are quite odiferous, and as a result contribute to bad breath.

<span class="mw-page-title-main">16-Androstene</span>

16-Androstenes, or androst-16-enes, are a class of endogenous androstane steroids that includes androstadienol, androstadienone, androstenone, and androstenol, which are pheromones. Some of the 16-androstenes, such as androstenone and androstenol, are odorous, and have been confirmed to contribute to human malodor.

<span class="mw-page-title-main">Eugene Rosenberg</span>

Eugene Rosenberg is a microbiologist at the Faculty of Life Sciences at Tel Aviv University, an expert in the field of applied environmental microbiology, in particular his work on Myxobacteria, microorganisms to combat pollution (bioremediation), and the Hologenome theory of evolution.

Oral health can be difficult for pet owners and veterinary teams to manage in cats, particularly for pets whose owners are not committed to regular tooth brushing and/or dental treats. Oral disease is common among cats, and may lead to other health issues such as bacterial infections of major organs including the heart, kidneys and liver. When pet owners are aware of the benefits of supporting good oral health in cats, this substantially improves positive outcomes. Dietary selection, along with at-home-dental-hygiene care, allows cat owners to influence the oral status of their pets.

Intestinal metabolic bromhidrosis syndrome (IMBS) is a disorder, that is characterized by bromhidrosis and halitosis symptoms that are caused by odorous intestinal metabolites passing through the intestinal wall and by the liver to be excreted by skin glands and the lung gas exchange.

References

  1. 1 2 Bad Breath Research – Tel-Aviv University, Mel Rosenberg's researcher site at Tel-Aviv University.
  2. 1 2 3 Rosenberg, Mel (2006). "Microbial adhesion to hydrocarbons: twenty-five years of doing MATH". FEMS Microbiology Letters. 262 (2): 129–134. doi: 10.1111/j.1574-6968.2006.00291.x . PMID   16923066.
  3. 1 2 Rosenberg, M.; Gutnick, D.; Rosenberg, E. (1980). "Adherence of bacteria to hydrocarbons: A simple method for measuring cell-surface hydrophobicity". FEMS Microbiology Letters. 9: 29–33. doi:10.1111/j.1574-6968.1980.tb05599.x.
  4. The citation classic of 1991 http://www.garfield.library.upenn.edu/classics1991/A1991FE76400001.pdf
  5. 1 2 Journal of Breath Research editorial, greeting its outgoing editor-in-chief, Mel Rosenberg.
  6. US patent 6465521 - Composition for desorbing bacteria.
  7. Dentyl Dual Action (Dentyl pH), The science behind Dentyl.
  8. Rosenberg, M.; Weiss, E. (1986). "The quadloop: a novel device for plating and streaking microbial samples". Journal of Microbiological Methods. 5 (5–6): 283–287. doi:10.1016/0167-7012(86)90053-9.
  9. Rosenberg, M.; Berger, S.A.; Barki, M.; Goldberg, S.; Fink, A.; Miskin, A. (1992). "Initial testing of a novel urine culture device". Journal of Clinical Microbiology. 30 (10): 2686–2691. doi: 10.1128/jcm.30.10.2686-2691.1992 . PMC   270499 . PMID   1400968.
  10. US patent 6439435 - Device and method for deodorizing shoes.
  11. US patent 7727515 - Body deodorant compositions and method.
  12. US patent 20100178256 - Oral anti-odor compositions.
  13. Rosenberg, M.; Kulkarni, G.V.; Bosy, A.; McCulloch, C.A. (1991). "Reproducibility and sensitivity of oral malodor measurements with a portable sulphide monitor". Journal of Dental Research. 70 (11): 1436–1440. doi:10.1177/00220345910700110801. PMID   1960254. S2CID   22605576.
  14. Rosenberg, M (2002). "The science of bad breath". Scientific American. 286 (4): 72–9. Bibcode:2002SciAm.286d..72R. doi:10.1038/scientificamerican0402-72. PMID   11905111.
  15. Journal of Breath Research editorial board, founding editors-in-chief.
  16. TED member profile.
  17. TED-ed animated video on halitosis.
  18. TED-ed animated video on dental caries.
  19. TED-ed animated video on what causes body odor.
  20. Tel Aviv Jazz Festival, roster announcement on the Jerusalem Post.
  21. Ourboox, an online platform for digital picture books - about the founders.
  22. Peachy Publications Q&A interview with Mel Rosenberg on Ourboox.
  23. IMDB.com, Mel Rosenberg's short biography on IMDB.com.