Methade

Methade

Names
Preferred IUPAC name N,N-Dimethyl-4,4-diphenylheptan-2-amine
Identifiers
CAS Number	875247-95-3  Y
3D model (JSmol)	Interactive image
ChemSpider	129556844
PubChem CID	71308237
CompTox Dashboard (EPA)	DTXSID901030352
InChI InChI=1S/C21H29N/c1-5-16-21(17-18(2)22(3)4,19-12-8-6-9-13-19)20-14-10-7-11-15-20/h6-15,18H,5,16-17H2,1-4H3 Key: MCFVCWVAZLRHPN-UHFFFAOYSA-N
SMILES CN(C(CC(CCC)(C1=CC=CC=C1)C2=CC=CC=C2)C)C
Properties
Chemical formula	C21H29N
Molar mass	295.470 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Methade, or 6-(dimethylamino)-4,4-diphenylheptane, is the parent compound of the methadone and methadol series of opioid analgesics: ^[1]

Chemical derivatives

The methade series includes the following compounds:

• Acetylmethadol
  • Alphacetylmethadol
    • Levacetylmethadol
  • Betacetylmethadol)
• Dimepheptanol (or methadol)
  • Alphamethadol
  • Betamethadol
• Methadone
  • Levomethadone
• Noracymethadol
• Normethadone

Related compounds

Some related compounds include:

• Alimadol
• Dextromoramide
• Dextropropoxyphene
• Dimenoxadol
• Dioxaphetyl butyrate
• Dipipanone
• Isomethadone
• Normethadone
• Norpipanone
• Phenadoxone

References

1. Perrine TD, May EL (1954). "Synthesis of 6-dimethylamino-4,4-diphenyl-heptane and other compounds related to methadone". Journal of Organic Chemistry . 19 (5): 773–779. doi:10.1021/jo01370a012. ISSN   1520-6904.