Mikesville, Florida | |
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| Coordinates: 29°56′48″N82°36′07″W / 29.94667°N 82.60194°W | |
| Country | United States |
| State | Florida |
| County | Columbia |
| Elevation | 151 ft (46 m) |
| Time zone | UTC-5 (Eastern (EST)) |
| • Summer (DST) | UTC-4 (EDT) |
| Area code | 386 |
| GNIS feature ID | 294854 [1] |
Mikesville is an unincorporated community in Columbia County, Florida, United States. [1] It is located along US Routes 41 and 441 with a short overlap of Columbia County Road 18 just north of O'Leno State Park.