Mississippi Highway 145 (MS 145) is the designation for the parts of the old U.S. Route 45 (US 45) roadbed that the state continues to maintain or has designated. Those ten sections travel through Waynesboro, near Boice, through Shubuta, from De Soto to Meridian, through Shuqualak, through Macon, through Aberdeen, through Nettleton, from Shannon to Booneville, and through Corinth.
Mississippi Highway 1 is a state highway in Mississippi that runs south from U.S. Highway 49 near Lula to U.S. Highway 61 south of Cary, roughly paralleling the Mississippi River. It travels approximately 148 miles (238 km), serving Sharkey, Issaquena, Washington, Bolivar, and Coahoma Counties. The entire route is part of the Great River Road and lies entirely within the Mississippi Delta region.
Mississippi Highway 3 is a north–south Mississippi state highway, located entirely within the Mississippi Delta region, running from Redwood to Lake Cormorant, both at an intersection with U.S. Route 61. For much of its duration, MS 3 is overlapped (concurrent) with U.S. Route 49W. It travels approximately 192 miles (309 km), serving DeSoto, Tunica, Tate, Panola, Quitman, Tallahatchie, Sunflower, Humphreys, Yazoo, and Warren counties.
Mississippi Highway 9 in the Appalachian Foothills region of northeastern Mississippi, running north–south from MS 30 east of New Albany to MS 12 in Ackerman. It runs approximately 116 miles (187 km), serving Choctaw, Webster, Calhoun, Pontotoc, and Union counties. MS 9W veers off to the left in a curve just about 2 miles north of Bruce. It goes north north-west until it merges with MS 7 just south of Oxford.
Mississippi Highway 28 (MS 28) is a state highway in south-central Mississippi, United States, that runs east–west from U.S. Highway 84 (US 84) west of Laurel to US 61/MS 33 in Fayette. It travels approximately 126 miles (203 km), serving Jefferson, Copiah, Simpson, Smith, and Jones counties.
Mississippi Highway 43 is a state highway in Mississippi that generally runs north–south in three segments: the first from US 90 near Bay St. Louis to MS 13 south of Columbia, resuming at MS 13 in southern Jefferson Davis County to end near Mendenhall, and finally starting again at MS 18 near Puckett to end at Attala Road 3122 in northern Attala County. It traverses approximately 235 miles (378 km), serving Hancock, Pearl River, Marion, Jefferson Davis, Lawrence, Simpson, Rankin, Madison, Leake, and Attala counties.
Mississippi Highway 35 is a state highway in Mississippi. It runs north–south for 274.7 miles (442.1 km), beginning at the Louisiana state line and ending at a junction with MS 315 at Sardis Dam. MS 35 serves the counties of Marion, Jefferson Davis, Covington, Smith, Scott, Leake, Attala, Carroll, Grenada, Tallahatchie, and Panola.
Mississippi Highway 26 (MS 26) is a 77.05-mile-long (124.00 km) state highway in southern Mississippi. It runs from a continuation of Louisiana Highway 10 (LA 10) east through Pearl River, Stone, and George counties to MS 198 in Lucedale. Along the way it intersects several major highways including U.S. Route 11 (US 11) in Poplarville, Interstate 59 (I-59) in Poplarville, and US 49 in Wiggins.
Mississippi Highway 32 is a state highway in northern Mississippi it runs from east to west for 152.0 miles (244.6 km), serving the counties of Bolivar, Sunflower, Tallahatchie, Yalobusha, Calhoun, and Chickasaw. The publicly accessible portion of MS 32 is divided into two sections, the first of which begins near Perthshire and runs eastward to the rear entrance of the Mississippi State Penitentiary (MSP). The second section begins at the main entrance of MSP and runs eastward to MS 32's terminus in Okolona. A private portion of MS 32 runs from the main entrance of MSP to the rear entrance of MSP.
Mississippi Highway 27 is a state highway in Mississippi. It runs from south to north for 120.9 miles (194.6 km) across the western and south-central parts of the state, serving 5 counties: Walthall, Lawrence, Copiah, Hinds, and Warren. The segment between Vicksburg and Crystal Springs is known vernacularly as the "Utica cutoff" because it facilitates a circumvention of Jackson for I-20 / I-55 traffic flowing between Vicksburg and Hammond.
Mississippi Highway 29 is a state highway in southern Mississippi. It runs from north to south for 78.7 miles (126.7 km) and serves three counties: Jones, Perry, Stone.
Mississippi Highway 21 is a state highway in central Mississippi. It runs from north to south for 80.3 miles (129.2 km) and serves six counties: Scott, Leake, Newton, Neshoba, Kemper, and Noxubee.
Mississippi Highway 48 is a state highway in southern Mississippi. It runs from east to west for 83.6 miles (134.5 km), serving a total of four counties: Marion, Walthall, Pike, and Amite.
Mississippi Highway 178 (MS 178), or simply "Old 78", is a 119.1-mile-long (191.7 km) east-west state highway across the northern portion of the state of Mississippi. It is the former alignment of U.S. Route 78 (US 78), used from the 1940s until the 1990s. With the exception of a break at the Tennessee-Tombigbee Waterway in Fulton, MS 178 is a complete route from Memphis, Tennessee, to the Alabama state line.
Mississippi Highway 44 (MS 44) is a 48.6-mile-long (78.2 km) disconnected state highway comprising three segments in south-central Mississippi.
Mississippi Highway 330 is a 33.271-mile-long (53.544 km) east-west state highway in the North Central Hills region of northern Mississippi, connecting U.S. Route 51 (US 51) just outside of Tillatoba to MS 32 west of Bruce, Mississippi. It is generally a two-lane road.
Mississippi Highway 341 is a 44.871-mile-long (72.213 km) north–south state highway in the North Central Hills region of northern Mississippi, connecting Hohenlinden with MS 9 near Pontotoc.
Mississippi Highway 613 is a 45.7-mile-long (73.5 km) north-south state highway in the eastern Mississippi Gulf Coast region of southeastern Mississippi. It connects the town of Lucedale with the city of Pascagoula.
Mississippi Highway 349 is a 17.1-mile-long (27.5 km) north–south state highway in the North Central Hills region of North Mississippi. It connects MS 30 to the town of Potts Camp ending at MS 178. All of MS 349 travels within Holly Springs National Forest. A loop of MS 349 runs to the east of the highway near Bethlehem is designated Mississippi Highway 347.
Mississippi Highway 356 is a 16.6-mile-long (26.7 km) east-west state highway in North Mississippi. It connects the communities of Hinkle, Pisgah, and Jacinto with the town of Rienzi.
MS 19 in Arlington 
MS 15 / MS 490 in Noxapater 
