Interstate 70 (I-70) is a major east–west Interstate Highway in the United States that runs from I-15 near Cove Fort, Utah, to a park and ride lot just east of I-695 in Baltimore, Maryland. I-70 approximately traces the path of U.S. Route 40 east of the Rocky Mountains. West of the Rockies, the route of I-70 was derived from multiple sources. The Interstate runs through or near many major cities, including Denver, Topeka, Kansas City, St. Louis, Indianapolis, Columbus, Pittsburgh, and Baltimore. The sections of the Interstate in Missouri and Kansas have laid claim to be the first Interstate in the United States. The Federal Highway Administration (FHWA) has claimed the section of I-70 through Glenwood Canyon, Colorado, completed in 1992, to be the last piece of the Interstate Highway System, as originally planned, to open to traffic. The construction of I-70 in Colorado and Utah is considered an engineering marvel, as the route passes through the Eisenhower Tunnel, Glenwood Canyon, and the San Rafael Swell. The Eisenhower Tunnel is the highest point along the Interstate Highway System, with an elevation of 11,158 feet (3,401 m).
Interstate 55 (I-55) is a major Interstate Highway in the central United States. As with most primary Interstates that end in a five, it is a major cross-country, north–south route, connecting the Gulf of Mexico to the Great Lakes. The highway travels from LaPlace, Louisiana, at I-10 to Chicago, Illinois, at U.S. Route 41, at McCormick Place. The major cities that I-55 connects to are New Orleans, Louisiana; Jackson, Mississippi; Memphis, Tennessee; St. Louis, Missouri; and Chicago, Illinois.
Interstate 64 (I-64) is an east–west Interstate Highway in the Eastern United States. Its western terminus is at I-70, U.S. Route 40 (US 40), and US 61 in Wentzville, Missouri. Its eastern terminus is at an interchange with I-264 and I-664 at Bower's Hill in Chesapeake, Virginia. I-64 connects the major metropolitan areas of St. Louis, Missouri; Louisville and Lexington in Kentucky; Charleston, West Virginia; and Richmond and Hampton Roads in Virginia.
Interstate 72 (I-72) is an Interstate Highway in the midwestern United States. Its western terminus is in Hannibal, Missouri, at an intersection with U.S. Route 61 (US 61); its eastern terminus is at Country Fair Drive in Champaign, Illinois. The route runs through the major cities of Decatur, Illinois, and Springfield, Illinois. In 2006, the Illinois General Assembly dedicated all of I-72 as Purple Heart Memorial Highway. The stretch between Springfield and Decatur is also called Penny Severns Memorial Expressway, and the section between mile 35 and the Mississippi River is known as the Free Frank McWorter Historic Highway.
Interstate 170 (I-170), also known as the Inner Belt Expressway, is an 11.17-mile (17.98 km) north–south auxiliary Interstate Highway in Greater St. Louis, Missouri. I-170 connects to I-270 at its northern terminus and I-64 at its southern terminus. I-170 crosses its parent, I-70, near St. Louis Lambert International Airport.
The Avenue of the Saints is a 563-mile-long (906 km) highway in the Midwestern United States that connects St. Louis, Missouri and St. Paul, Minnesota.
Interstate 255 (I-255) is a bypass route of I-55 in Greater St. Louis. Along with I-270, it forms a loop around the central portion of the bi-state metro area; a majority of I-255 is located on the Illinois half. It shares its southern terminus with I-270 at the junction with I-55; I-270 and I-255 go to the west and east, respectively. U.S. Route 50 (US 50) joins I-255 at Lemay Ferry Road. It crosses the Mississippi River on the Jefferson Barracks Bridge, enters Illinois, and then turns northeast. There is a junction with I-64, where US 50 breaks off and goes east, and then further north there is a junction with I-55 again, I-70, and US 40, all of which are all cosigned together. The next junction is another one with I-270, which is the northern terminus of I-255. After that, the limited-access freeway continues on as Illinois Route 255 (IL 255). I-255 is 30.82 miles (49.60 km) in length.
Missouri Route 370 (Route 370) is a freeway that connects St. Louis County with St. Charles County via the Discovery Bridge over the Missouri River. The St. Charles County segment of the freeway is signed as the Patrick J. Bray Memorial Highway.
Route 571 is a two-lane highway in Carthage, Missouri, replacing a former section of U.S. Route 71 Alternate (US 71 Alt.) with the realignment of US 71. Both termini are at Interstate 49 (I-49) and US 71; its northern terminus is Business I-49 and Route 171 at the western edge of Carthage and its southern terminus is I-49/US 71 at the southern edge of Carthage.
Route 367 is a 8.9-mile (14.3 km) long roadway in the metropolitan St. Louis, Missouri, United States area. It is also known as Lewis & Clark Boulevard. Its northern terminus is U.S. Route 67 (US 67) near Black Jack and its southern terminus is at the Interstate 70 (I-70) bridge over Riverview Boulevard before Riverview Boulevard becomes Bircher Boulevard in St. Louis. It was originally part of US 67.
Route 30 is a highway in eastern Missouri, United States. Its eastern terminus is at the Interstate 55/Interstate 44 junction in St. Louis. Its western terminus is at Interstate 44 in St. Clair. In St. Louis, the section between Interstate 44 and Route 366 is part of historic U.S. Route 66 and is marked as such. In the St. Louis area, it is known as Gravois Avenue or Gravois Road. Further south, Gravois Rd is used to mark the old section of the highway where the newer, divided highway rerouted Highway 30.
Interstate 270 (I-270) makes up a large portion of the outer belt freeway in Greater St. Louis. The counterclockwise terminus of I-270 is at the junction with I-55 and I-255 in Mehlville, Missouri; the clockwise terminus of the freeway is at the junction with I-55 and I-70 north of Troy, Illinois. The entire stretch of I-270 is 50.59 miles (81.42 km).
Interstate 470 (I-470) is a 16.72-mile (26.91 km) loop of the Interstate Highway System that serves to link southeast Kansas City to Independence via Lee's Summit in Jackson County, Missouri. The western terminus of the freeway is at the Grandview Triangle interchange with I-49, I-435, U.S. Route 50 (US 50), and US 71 while the northern terminus is a cloverleaf interchange with I-70. The freeway travels west to east through southern Kansas City, curving toward the north at the Lee's Summit Municipal Airport and becoming concurrent with Route 291 as the highway travels north toward Independence.
Transportation in Greater St. Louis, Missouri includes road, rail, ship, and air transportation modes connecting the bi-state St. Louis metropolitan area with surrounding communities throughout the Midwest, national transportation networks, and international locations. The Greater St. Louis region also supports a multi-modal transportation network that includes bus, paratransit, and light rail service in addition to shared-use paths, bike lanes and greenways.
Interstate 55 (I-55) is a major north–south Interstate Highway in the US state of Illinois that connects St. Louis, Missouri, to the Chicago metropolitan area. It enters the state from Missouri near East St. Louis, Illinois, and runs to U.S. Route 41 near Downtown Chicago, where the highway ends, a distance of 294.38 miles (473.76 km). The road also runs through the Illinois cities of Springfield, Bloomington, and Joliet. The section in Cook County is officially named the Stevenson Expressway, and in DuPage County its officially named the Joliet Freeway or the Will Rogers Freeway. The section from the south suburbs of Chicago to the area near Pontiac is officially named the Barack Obama Presidential Expressway after the 44th President, Barack Obama, who launched his political career from Illinois.
Interstate 70 (I-70) in the US state of Missouri is generally parallel to the Missouri River. This section of the transcontinental Interstate begins at the Kansas state line on the Intercity Viaduct, running concurrently with US Route 24 (US 24), US 40, and US 169, and the east end is on the Stan Musial Veterans Memorial Bridge in St. Louis.
Interstate 64 (I-64) passes through the Greater St. Louis area in the US state of Missouri. The entire route overlaps U.S. Route 40 (US 40). Because the road was a main thoroughfare in the St. Louis area before the development of the Interstate Highway System, it is not uncommon for locals to refer to the stretch of highway as "Highway 40" rather than "I-64". On December 6, 2009, the portion of the highway running through the city of St. Louis was named the Jack Buck Memorial Highway in honor of the late sportscaster.
Interstate 44 (I-44) in the US state of Missouri runs northeast from the Oklahoma state line near Joplin to I-70 in Downtown St. Louis. It runs for about 293 miles (472 km) in the state, and is the longest Interstate Highway in the state.
Interstate 55 (I-55) is a north–south Interstate Highway that has a 72.22-mile (116.23 km) section in the US state of Arkansas connecting sections in Tennessee and Missouri. The route enters Arkansas on the Memphis & Arkansas Bridge over the Mississippi River from Memphis. It travels northward through northeast Arkansas, connecting the cities of West Memphis and Blytheville. I-55 continues into Missouri heading to St. Louis, Missouri. The highway overlaps I-40 in West Memphis and has a junction with I-555, a spur route to Jonesboro, in Turrell. For the majority of its routing through Arkansas, I-55 generally follows U.S. Highway 61 (US 61).
U.S. Route 67 is the portion of a north-south highway in Missouri that starts at the Arkansas state line south of Neelyville and ends at the Illinois state line northeast of West Alton.
I-70 in Berkeley 
I-170 in Bel-Ridge 
