NXPH3

NXPH3
Identifiers
Aliases	NXPH3 , NPH3, neurexophilin 3
External IDs	OMIM: 604636 MGI: 1336188 HomoloGene: 5227 GeneCards: NXPH3
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q21.33 Start 49,575,871 bp [1] End 49,583,827 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 D Start 95,400,671 bp [2] End 95,405,396 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ascending aorta vena cava saphenous vein right coronary artery cerebellar hemisphere popliteal artery pons gastric mucosa subthalamic nucleus superficial temporal artery Top expressed in olfactory epithelium visual cortex urethra female urethra male urethra temporal muscle carotid body superior frontal gyrus vastus lateralis muscle sternocleidomastoid muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signaling receptor binding molecular function Cellular component extracellular region Biological process neuropeptide signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11248 104079 Ensembl ENSG00000182575 ENSMUSG00000046719 UniProt O95157 Q91VX5 RefSeq (mRNA) NM_007225 NM_130858 RefSeq (protein) NP_009156 NP_570928 Location (UCSC) Chr 17: 49.58 – 49.58 Mb Chr 11: 95.4 – 95.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Neurexophilin-3 is a protein that in humans is encoded by the NXPH3 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000182575 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000046719 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Missler M, Sudhof TC (Jun 1998). "Neurexophilins form a conserved family of neuropeptide-like glycoproteins". J Neurosci. 18 (10): 3630–8. doi: 10.1523/JNEUROSCI.18-10-03630.1998 . PMC   6793134 . PMID   9570794.
6. "Entrez Gene: NXPH3 neurexophilin 3".

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC   2286551 . PMID   15340161.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hirosawa M, Nagase T, Ishikawa K, et al. (2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi: 10.1093/dnares/6.5.329 . PMID   10574461.
• Missler M, Hammer RE, Südhof TC (1999). "Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit". J. Biol. Chem. 273 (52): 34716–23. doi: 10.1074/jbc.273.52.34716 . PMID   9856994.
• Petrenko AG, Ullrich B, Missler M, et al. (1996). "Structure and evolution of neurexophilin". J. Neurosci. 16 (14): 4360–9. doi: 10.1523/JNEUROSCI.16-14-04360.1996 . PMC   6578849 . PMID   8699246.