The Novo Nordisk Foundation Center for Protein Research was established at the Faculty of Health and Medical Sciences at the University of Copenhagen, to promote basic and applied discovery research on human proteins of medical relevance. The establishment of the center (announced in April 2007) has been made possible by a donation of 600 million DKK (~113 MUSD) from the Novo Nordisk Foundation and through significant contributions from the University of Copenhagen for the renovation of the Center laboratories. [1]
The Center comprises a wide range of expertise and skills within research areas of disease systems biology, proteomics, high throughput protein production and characterisation, chemical biology, disease biology, and protein therapeutics. The Center also contributes to the progress of translational research within medicine and provide fundamental insights which can be used to promote drug discovery and development.
Susan Lee Lindquist, ForMemRS was an American professor of biology at MIT specializing in molecular biology, particularly the protein folding problem within a family of molecules known as heat-shock proteins, and prions. Lindquist was a member and former director of the Whitehead Institute and was awarded the National Medal of Science in 2010.
The University of Copenhagen (UCPH) is the oldest university and research institution in Denmark. Founded in 1479 as a studium generale, it is the second oldest institution for higher education in Scandinavia after Uppsala University (1477). The university today is state-funded, and has 23,473 undergraduate students, 17,398 postgraduate students, 2,968 doctoral students and over 9,000 employees. The university has four campuses located in and around Copenhagen, with the headquarters located in central Copenhagen. Most courses are taught in Danish; however, many courses are also offered in English and a few in German. The university has several thousands of foreign students, about half of whom come from Nordic countries.
Leroy "Lee" Edward Hood is an American biologist who has served on the faculties at the California Institute of Technology (Caltech) and the University of Washington. Hood has developed ground-breaking scientific instruments which made possible major advances in the biological sciences and the medical sciences. These include the first gas phase protein sequencer (1982), for determining the amino acids that make up a given protein; a DNA synthesizer (1983), to synthesize short sections of DNA; a peptide synthesizer (1984), to combine amino acids into longer peptides and short proteins; the first automated DNA sequencer (1986), to identify the order of nucleotides in DNA; ink-jet oligonucleotide technology for synthesizing DNA and nanostring technology for analyzing single molecules of DNA and RNA.
Schack August Steenberg Krogh was a Danish professor at the department of zoophysiology at the University of Copenhagen from 1916 to 1945. He contributed a number of fundamental discoveries within several fields of physiology, and is famous for developing the Krogh Principle.
The Faculty of Health and Medical Sciences at the University of Copenhagen houses 13 departments, 31 centres, five schools, four hospitals, and three libraries.
Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd, Denmark, with production facilities in eight countries, and affiliates or offices in 5 countries. Novo Nordisk is controlled by majority shareholder Novo Holdings A/S which holds approximately 25% of its shares and a supermajority (45%) of its voting shares.
Alexander Jacob Varshavsky is a Russian-American biochemist, noted for his discovery of the N-end rule of ubiquitination. A native of Moscow, he is currently researching at Caltech.
Matthias Mann is a scientist in the area of mass spectrometry and proteomics.
Sanford Burnham Prebys Medical Discovery Institute (SBP) is a 501(c)(3) non-profit medical research institute focusing on basic and translational research, with major research programs in cancer, neurodegeneration, diabetes, and infectious, inflammatory, and childhood diseases. The Institute also specializes in stem cell research and drug discovery technologies.
Robert Joseph Lefkowitz is an American physician and biochemist. He is best known for his groundbreaking discoveries that reveal the inner workings of an important family G protein-coupled receptors, for which he was awarded the 2012 Nobel Prize for Chemistry with Brian Kobilka. He is currently an Investigator with the Howard Hughes Medical Institute as well as a James B. Duke Professor of Medicine and Professor of Biochemistry and Chemistry at Duke University.
Medicon Valley is a leading international life-sciences cluster in Europe, spanning the Greater Copenhagen region of eastern Denmark and southern Sweden. It is one of Europe's strongest life science clusters, with many life science companies and research institutions located within a relatively small geographical area. The name has officially been in use since 1997.
Søren Brunak, Ph.D. is a Danish biological and physical scientist working in bioinformatics, systems biology and medical informatics. He is professor of Disease Systems Biology at the University of Copenhagen and professor of Bioinformatics at the Technical University of Denmark. As Research Director at the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen Medical School he leads a research effort where molecular level systems biology data are combined with phenotypic data from the healthcare sector, such as electronic patient records, registry information and biobank questionnaires. A major aim is to understand the network biology basis for time-ordered comorbidities and discriminate between treatment related disease correlations and other comorbidities in disease trajectories. Søren Brunak also holds a position as Medical Informatics Officer at Rigshospitalet, Capital Region of Denmark.
Jeffrey I. Gordon is a biologist and the Dr. Robert J. Glaser Distinguished University Professor and Director of the Center for Genome Sciences and Systems Biology at Washington University in St. Louis. He is internationally known for his research on gastrointestinal development and how gut microbial communities affect normal intestinal function, shape various aspects of human physiology including our nutritional status, and affect predisposition to diseases. He is a member of the National Academy of Sciences, the American Academy of Arts and Sciences and the Institute of Medicine of the National Academies.
The Copenhagen Institute of Interaction Design (CIID) is a postgraduate school and consultancy based in Copenhagen, Denmark which focuses on the area of interaction design.
Ram Samudrala is a professor of computational biology and bioinformatics at the University at Buffalo, and formerly at the University of Washington in Seattle, United States. He researches protein and proteome folding, structure, function, interaction, design, and evolution spanning atomic to organismal levels of description. He has published more than 120 manuscripts in a variety of journals including Science, Nature, PLoS Biology, Drug Discovery Today, the Proceedings of the National Academy of Sciences, and the Journal of the American Medical Association.
Biopeople - Denmark's Life Science Cluster is a publicly funded partnership and National Center established, authorised, and funded by the Ministry for Science and Higher Education to improve innovation, collaboration and education within the National Danish Innovation System. Biopeople is established as a Center at the Faculty of Health and Medical Sciences at University of Copenhagen.
Maiken Nedergaard is a Danish neuroscientist most well known for discovering the glymphatic system. She is a jointly appointed professor in the Departments of Neuroscience and Neurology at the University of Rochester Medical Center. She holds a part-time appointment in the Department of Neurosurgery within the University of Rochester Center for Translational Neuromedicine, where she is the principal investigator of the Division of Glial Disease and Therapeutics laboratory. She is also Professor of Glial Cell Biology at the University of Copenhagen, Center for Translational Neuromedicine.
David Chaim Rubinsztein FRS FMedSci is the Deputy Director of the Cambridge Institute of Medical Research (CIMR), the Academic Lead of the Alzheimer's Research UK (ARUK) Cambridge Drug Discovery Institute,, Professor of Molecular Neurogenetics at the University of Cambridge. and a UK Dementia Research Institute Professor.
The Novo Nordisk Foundation is an international foundation focusing on medical treatment and research. In 2018, the foundation had a net worth of US$49.1 billion, making it the largest financial endowment of any foundation in Denmark and one of the largest endowments in the world.
Gökhan S. Hotamisligil is a Turkish-American physician scientist; James Stevens Simmons Chair of Genetics and Metabolism; Department of Genetics and Complex Diseases at Harvard T.H. Chan School of Public Health (HSPH); Director of the Sabri Ülker Center for Metabolic Research and associate member of Harvard-MIT Broad Institute, Harvard Stem Cell Institute and the Joslin Diabetes Center.