Ophidascaris robertsi

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Ophidascaris robertsi
Scientific classification OOjs UI icon edit-ltr.svg
Domain: Eukaryota
Kingdom: Animalia
Phylum: Nematoda
Class: Chromadorea
Order: Ascaridida
Family: Ascarididae
Genus: Ophidascaris
Species:
O. robertsi
Binomial name
Ophidascaris robertsi
(Sprent & Mines, 1960) [1]
Synonyms [1]

Amplicaecum robertsiSprent & Mines, 1960 [2]

Ophidascaris robertsi is a nematode (also known as roundworm) [3] usually parasitic in the carpet python (Morelia spilota). [4] It is found in Australia and Papua New Guinea. Pythons serve as the typical hosts for Ophidascaris robertsi, which has an indirect life cycle. The adult parasites develop nodular masses in the oesophagus and stomach of carpet pythons and place a small piece of their anterior bodies into the nodules that protrude from the digestive mucosa. When endemic parasites like Ophidascaris robertsi infect local fauna, the pathological changes that follow are frequently self-limiting or do not result in illness. [5]

Contents

Description

Identification of Ophidascaris robertsi from closely related species such as Ophidascaris moreliae is noted to be difficult, depending on the morphology of the egg surface, if cervical alae or post-oesophageal caeca are present, and the shape of the lips. [6]

Hosts

Reported infections in pythons include Antaresia childreni (children's python), Aspidites melanocephalus (black-headed python), Aspidites ramsayi (woma python), and Morelia spilota (carpet python). [6] There are also reports of infections in a sugar glider (Petaurus breviceps), a koala (Phascolarctos cinereus), a bandicoot (Perameles nasuta) and in other small to medium-sized marsupial species. [7] [8] [9] One case report of zoonotic infection in a human brain from Australia during 2021–22 was reported in August 2023. [4] [10]

A 2021 study on host loss in parasite species used Ophidascaris robertsi as one of the subject taxa. [11]

Human infection

In June 2022, a neurosurgeon in an Australian hospital found a roundworm in a woman's brain while investigating her mysterious symptoms. [4] The woman initially reported diarrhea and abdominal pain, along with night sweats and dry cough, and was originally diagnosed with a rare lung infection. [12] Though her symptoms improved with treatment, she subsequently returned with symptoms of fever and cough, resulting in an additional diagnosis of a blood disorder. Worsening symptoms of forgetfulness and depression resulted in an MRI that revealed a brain lesion. The biopsy resulted in the discovery and extraction of the live worm. [12] This was the first known instance of such an occurrence, as this type of worm had never been identified as a human parasite before. [4] [10] [13] The woman, who lived near carpet python habitat and foraged for native vegetation to cook, was believed to have been exposed by consuming the roundworm’s eggs. These eggs, which were commonly shed in snake droppings due to the snakes' diet of infected animals, likely contaminated the grass eaten by small mammals. [4] [13] [3] Doctors theorize that the various symptoms experienced by the patient resulted from the migration of the parasitic eggs and larva from the bowel, through various other organs, before arriving in the brain. [12]

Related Research Articles

<span class="mw-page-title-main">Koala</span> Arboreal herbivorous marsupial native to Australia

The koala, sometimes called the koala bear, is an arboreal herbivorous marsupial native to Australia. It is the only extant representative of the family Phascolarctidae and its closest living relatives are the wombats. The koala is found in coastal areas of the mainland's eastern and southern regions, inhabiting Queensland, New South Wales, Victoria, and South Australia. It is easily recognisable by its stout, tailless body and large head with round, fluffy ears and large, dark nose. The koala has a body length of 60–85 cm (24–33 in) and weighs 4–15 kg (9–33 lb). Fur colour ranges from silver grey to chocolate brown. Koalas from the northern populations are typically smaller and lighter in colour than their counterparts further south. These populations possibly are separate subspecies, but this is disputed.

<span class="mw-page-title-main">Pythonidae</span> Family of snakes

The Pythonidae, commonly known as pythons, are a family of nonvenomous snakes found in Africa, Asia, and Australia. Among its members are some of the largest snakes in the world. Ten genera and 39 species are currently recognized. Being naturally non-venomous, pythons must constrict their prey to suffocate it prior to consumption. Pythons will typically strike at and bite their prey of choice to gain hold of it; they then must use physical strength to constrict their prey, by coiling their muscular bodies around the animal, effectively suffocating it before swallowing whole. This is in stark contrast to venomous snakes such as the rattlesnake, for example, which delivers a swift, venomous bite but releases, waiting as the prey succumbs to envenomation before being consumed. Collectively, the pythons are well-documented and -studied as constrictors, much like other non-venomous snakes, including the boas and even kingsnakes of the New World.

<i>Ascaris lumbricoides</i> One of several species of Ascaris

Ascaris lumbricoides is a large parasitic worm that causes ascariasis in humans. A roundworm of genus Ascaris, it is the most common parasitic worm in humans. An estimated 807 million–1.2 billion people are infected with A. lumbricoides worldwide. People living in tropical and subtropical countries are at greater risk of infection.

<span class="mw-page-title-main">Phascolarctidae</span> Family of marsupials

The Phascolarctidae is a family of marsupials of the order Diprotodontia, consisting of only one extant species, the koala, and six well-known fossil species, with another six less well known fossil species, and two fossil species of the genus Koobor, whose taxonomy is debatable but are placed in this group. The closest relatives of the Phascolarctidae are the wombats, which comprise the family Vombatidae.

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<i>Morelia spilota</i> Species of snake

Morelia spilota, commonly known as the carpet python, is a large snake of the family Pythonidae found in Australia, New Guinea, Bismarck Archipelago, and the northern Solomon Islands. Many subspecies are recognised; ITIS lists six, the Reptile Database six, and the IUCN eight.

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Chlamydia pecorum, also known as Chlamydophila pecorum is a species of Chlamydiaceae that originated from ruminants, such as cattle, sheep and goats. It has also infected koalas and swine. C. pecorum strains are serologically and pathogenically diverse.

Mammomonogamus is a genus of parasitic nematodes of the family Syngamidae that parasitise the respiratory tracts of cattle, sheep, goats, deer, cats, orangutans, and elephants. The nematodes can also infect humans and cause the disease called mammomonogamiasis. Several known species fall under the genus Mammomonogamus, but the most common species found to infest humans is M. laryngeus. Infection in humans is very rare, with only about 100 reported cases worldwide, and is assumed to be largely accidental. Cases have been reported from the Caribbean, China, Korea, Thailand, and Philippines.

<i>Dioctophyme renale</i> Species of roundworm

Dioctophyme renale, commonly referred to as the giant kidney worm, is a parasitic nematode (roundworm) whose mature form is found in the kidneys of mammals. D. renale is distributed worldwide, but is less common in Africa and Oceania. It affects fish-eating mammals, particularly mink and dogs. Human infestation is rare, but results in kidney destruction, usually of one kidney and hence not fatal. A 2019 review listed a total of 37 known human cases of dioctophymiasis in 10 countries with the highest number (22) in China. Upon diagnosis through tissue sampling, the only treatment is surgical excision.

<i>Toxocara canis</i> Species of roundworm

Toxocara canis is a worldwide-distributed helminth parasite that primarily infects dogs and other canids, but can also infect other animals including humans. The name is derived from the Greek word "toxon," meaning bow or quiver, and the Latin word "caro," meaning flesh. T. canis live in the small intestine of the definitive host. This parasite is very common in puppies and somewhat less common in adult dogs. In adult dogs, infection is usually asymptomatic but may be characterized by diarrhea. By contrast, untreated infection with Toxocara canis can be fatal in puppies, causing diarrhea, vomiting, pneumonia, enlarged abdomen, flatulence, poor growth rate, and other complications.

Angiostrongyliasis is an infection by a roundworm of the Angiostrongylus type. Symptoms may vary from none, to mild, to meningitis.

<i>Morelia spilota spilota</i> Subspecies of snake

Morelia spilota spilota is a subspecies of carpet python, popularly known as the diamond python. It is a medium to large snake, found in coastal areas and adjacent ranges of south-eastern Australia. It is the most southerly occurring python in the world and is found at higher altitudes than any other species of Australian python.

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<i>Morelia imbricata</i> Species of snake

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<i>Angiostrongylus cantonensis</i> Species of roundworm

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<i>Toxascaris leonina</i> Species of roundworm

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<i>Baylisascaris procyonis</i> Species of roundworm

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Trypanosoma irwini is a blood parasite of koalas. First discovered in 2009 by Linda M. McInnes and her peers, it was named in honor of Steve Irwin, "The Crocodile Hunter". The study done by McInnes et al. was the first to describe a Trypanosoma species from koalas.

References

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  2. Sprent, J. F. A.; Mines, J. J. (1960). "A new species of Amplicaecum (Nematoda) from the carpet snake (Morelia argus variegatus): with a re-definition and a key for the genus". Parasitology. 50 (1–2): 183–198. doi:10.1017/S0031182000025282. PMID   13833462. S2CID   20230177.
  3. 1 2 McGuirk, Rod (2023-08-29), "Neurosurgeon investigating patient's mystery symptoms plucks a worm from woman's brain in Australia", Associated Press , retrieved 2023-10-14
  4. 1 2 3 4 5 Hossein ME, Kennedy KJ, Wilson HL, Spratt D, Koehler A, Gasser RB, Šlapeta J, Hawkins CA, Bandi HP, Senanayake SN (Sep 2023). "Human neural larva migrans caused by Ophidascaris robertsi ascarid". Emerging Infectious Diseases. 29 (9): 1900–1903. doi:10.3201/eid2909.230351. PMC   10461669 . PMID   37610238. S2CID   261073909.
  5. Gonzalez‐Astudillo, Viviana; Knott, Lyn; Valenza, Ludovica; Henning, Joerg; Allavena, Rachel (June 2019). "Parasitism by Ophidascaris robertsi with associated pathology findings in a wild koala ( Phascolarctos cinereus )". Veterinary Record Case Reports. 7 (2). doi: 10.1136/vetreccr-2019-000821 . S2CID   164545824.
  6. 1 2 Barton, Diane P.; Jones, Hugh I. (2018). "Nematodes from northern Australian reptiles" (PDF). Northern Territory Naturalist. 28: 43–60.
  7. Agúndez, MG; Rodríguez, JE; Juan-Sallés, C; Spratt, DM (Dec 2014). "First report of parasitism by Ophidascaris robertsi (Nematoda) in a sugar glider (Petaurus breviceps, Marsupialia)". Journal of Zoo and Wildlife Medicine. 45 (4): 984–986. doi:10.1638/2014-0107.1. PMID   25632698. S2CID   38724780.
  8. Gonzalez‐Astudillo, Viviana; Knott, Lyn; Valenza, Ludovica; Henning, Joerg; Allavena, Rachel (2019). "Parasitism by Ophidascaris robertsi with associated pathology findings in a wild koala (Phascolarctos cinereus)". Veterinary Record Case Reports. 7 (2): e000821. doi: 10.1136/vetreccr-2019-000821 . S2CID   164545824.
  9. MacGregor, Christopher I.; Wood, Jeff T.; Dexter, Nick; Lindenmayer, David B. (2013). "Home range size and use by the long-nosed bandicoot (Perameles nasuta) following fire". Australian Mammalogy. 35 (2): 206. doi:10.1071/AM12032. hdl: 1885/64571 .
  10. 1 2 Phil Mercer (29 August 2023). "Live worm found in Australian woman's brain in world first". BBC News, Sydney. Retrieved 29 August 2023.
  11. Farrell, M.J.; Park, A.W.; Cressler, C.E.; Dallas, T.; Huang, S.; Mideo, N.; Morales-Castilla, I.; Davies, T.J.; Stephens, P. (2021). "The ghost of hosts past: impacts of host extinction on parasite specificity". Philosophical Transactions of the Royal Society B. 376 (1837). doi:10.1098/rstb.2020.0351. PMC   8450631 . PMID   34538147. S2CID   237565364.
  12. 1 2 3 "She Was Depressed and Forgetful. It Was the Worm in Her Brain". New York Times . 2023-08-29. Retrieved 2023-09-01.
  13. 1 2 Mole, Beth (2023-08-28). "Woman's mystery illness turns out to be 3-inch snake parasite in her brain". Ars Technica . Retrieved 2023-08-30.