Orange B

Last updated
Orange B
Acid Orange 137.png
Orange B ball-and-stick.png
Names
IUPAC name
Disodium 4-[N'-[3-ethoxycarbonyl-5-oxo-1-(4-sulfonatophenyl)-4-pyrazolylidene]hydrazino]-1-naphthalenesulfonate
Other names
C.I. Acid Orange 137; CI 19235
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.035.622 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 239-201-5
PubChem CID
UNII
  • InChI=1S/C22H18N4O9S2.2Na/c1-2-35-22(28)20-19(21(27)26(25-20)13-7-9-14(10-8-13)36(29,30)31)24-23-17-11-12-18(37(32,33)34)16-6-4-3-5-15(16)17;;/h3-12,27H,2H2,1H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2/b24-23+;; Yes check.svgY
    Key: LLTKITSFUJSOCC-KPOOZVEVSA-L Yes check.svgY
  • InChI=1/C22H18N4O9S2.2Na/c1-2-35-22(28)20-19(21(27)26(25-20)13-7-9-14(10-8-13)36(29,30)31)24-23-17-11-12-18(37(32,33)34)16-6-4-3-5-15(16)17;;/h3-12,27H,2H2,1H3,(H,29,30,31)(H,32,33,34);;/q;2*+1/p-2/b24-23+;;
    Key: LLTKITSFUJSOCC-AQVGDJFIBI
  • [Na+].[Na+].[O-]S(=O)(=O)c4ccc(/N=N/c2c(nn(c1ccc(cc1)S([O-])(=O)=O)c2O)C(=O)OCC)c3ccccc34
Properties
C22H16N4Na2O9S2
Molar mass 590.49 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
X mark.svgN  verify  (what is  Yes check.svgYX mark.svgN ?)

Orange B is a food dye from the azo dye group. It is approved by the United States Food and Drug Administration (FDA) for use only in hot dog and sausage casings or surfaces, up to 150 parts per million of the finished food weight. [1] It is typically prepared as a disodium salt. [1]

Orange B was first approved by the FDA for use as a certified food dye in 1966. However, in 1978, the FDA proposed removing it from the list of approved food additives due to concerns over potential carcinogenic contaminants, particularly the presence of 2-naphthylamine. Around the same time, its sole U.S. manufacturer, the William J. Stange Company, ceased production. Despite its non-use in food products since the late 20th century, the FDA did not formally revoke its approval. [2]

On April 22, 2025, the FDA announced plans to phase out synthetic food dyes by the end of 2026. This decision, led by FDA Commissioner Martin Makary, was driven by growing concerns over the potential health risks associated with synthetic food dyes. As part of this phase-out, the FDA revealed its intention to revoke approval for Orange B, along with another restricted-use dye, Citrus Red 2. [3]

References

  1. 1 2 "Code of Federal Regulations: Title 21, Section 74.250". U.S. Food and Drug Administration. Retrieved 24 December 2012.
  2. ↑ Hathcock, John N. (1982). Nutritional Toxicology. New York: Academic Press. pp. 407–408. ISBN   012332601X.
  3. ↑ Choi, Joseph (2025-04-22). "FDA announces plans to phase out petroleum-based food dyes". The Hill. Retrieved 2025-04-24.


This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.