Phosphonoacetate hydrolase

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phosphonoacetate hydrolase
1ei6.png
Structure of phosphonoacetate hydrolase. PDB entry 1e16 . Zinc ions and phosphonoformate are shown in the active site.
Identifiers
EC no. 3.11.1.2
CAS no. 153570-68-4
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In enzymology, a phosphonoacetate hydrolase (EC 3.11.1.2) is an enzyme that catalyzes the chemical reaction

Contents

phosphonoacetate + H2O acetate + phosphate

Thus, the two substrates of this enzyme are phosphonoacetate and H2O, whereas its two products are acetate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-phosphorus bonds. The systematic name of this enzyme class is phosphonoacetate phosphonohydrolase. This enzyme participates in aminophosphonate metabolism. It employs one cofactor, zinc.

Structural studies

The structure of this enzyme, with the PDB accession code 1EI6, shows it adopts the alkaline phosphatase fold.

Related Research Articles

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References


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