Pimeloyl chloride

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Pimeloyl chloride
Pimeloyl chloride.svg
Names
Preferred IUPAC name
Heptanedioyl dichloride
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.005.056
EC Number 205-561-7
PubChem CID
Properties
C7H10Cl2O2
Molar mass 197.06 g·mol−1
Hazards
GHS pictograms GHS-pictogram-acid.svg GHS-pictogram-exclam.svg
GHS signal word Danger
H315, H318, H335
P260, P261, P264, P271, P280, P301+330+331, P303+361+353, P304+340, P305+351+338, P310, P312, P321, P363, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Pimeloyl chloride is a di-acyl chloride. It is used as a reagent in organic synthesis.

Acyl chloride any chemical compound having a chlorine atom bonded to a carboacyl group

In organic chemistry, an acyl chloride (or acid chloride) is an organic compound with the functional group -COCl. Their formula is usually written RCOCl, where R is a side chain. They are reactive derivatives of carboxylic acids. A specific example of an acyl chloride is acetyl chloride, CH3COCl. Acyl chlorides are the most important subset of acyl halides.

Synthesis

Pimeloyl chloride can be synthesized from pimelic acid in thionyl chloride. [1]

Pimelic acid chemical compound

Pimelic acid is the organic compound with the formula HO2C(CH2)5CO2H. Derivatives of pimelic acid are involved in the biosynthesis of the amino acid called lysine. Pimelic acid is one CH
2
unit
longer than a related dicarboxylic acid, adipic acid, a precursor to many polyesters and polyamides. It is the final member of the mnemonic used to aid recollection of the order of the first six dicarboxylic acids using their common (not IUPAC) nomenclature: Dicarboxylic acid

Thionyl chloride chemical compound

Thionyl chloride is an inorganic compound with the chemical formula SOCl2. It is a moderately volatile colourless liquid with an unpleasant acrid odour. Thionyl chloride is primarily used as a chlorinating reagent, with approximately 45,000 tonnes (50,000 short tons) per year being produced during the early 1990s. It is toxic, reacts with water, and is also listed under the Chemical Weapons Convention as it may be used for the production of chemical weapons.

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References

  1. US 2014256775,CHEN LIN [US]; CHEN XIAOJIANG [US]; WU YONGQING[US]; GAI DAHAI [US],"NOVEL TRANSCRIPTION FACTOR MODULATORS"