Polynoxylin

Polynoxylin
Clinical data
Routes of; administration	Topical
ATC code	A01AB05 ( WHO ) D01AE05 ( WHO );
Identifiers
	IUPAC name (poly) methylene-N,N'-bis(hydroxymethyl)urea;
CAS Number	9011-05-6 ;
ChemSpider	none;
UNII	E18NBG5EEY ;
KEGG	D07067 ;
CompTox Dashboard (EPA)	DTXSID10905739 DTXSID00891874, DTXSID10905739 ;
ECHA InfoCard	100.108.096
Chemical and physical data
Formula	(C4H8N2O3)n
	(verify)

Last updated December 27, 2025

Polynoxylin (trade name Anaflex in Egypt^[1]) is an antiseptic for local treatment of the skin and the mouth. It is a formaldehyde releasing antimicrobial polymer.^[2]

References

↑ International Drug Names : Anaflex 10%. Accessed 2020-08-01.
↑ Kingston D (September 1965). "Release of formaldehyde from polynoxylin and noxythiolin". Journal of Clinical Pathology. 18 (5): 666–7. doi:10.1136/jcp.18.5.666. PMC 473043 . PMID 5835451.

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[1] International Drug Names : Anaflex 10%. Accessed 2020-08-01.

[2] Kingston D (September 1965). "Release of formaldehyde from polynoxylin and noxythiolin". Journal of Clinical Pathology. 18 (5): 666–7. doi:10.1136/jcp.18.5.666. PMC 473043 . PMID 5835451.

[1]

[2]

v t e Stomatological preparations (A01)
Caries prophylaxis	Dectaflur Olaflur Sodium fluoride Sodium monofluorophosphate Stannous fluoride
Infection and antiseptics	Amphotericin B Benzoxonium chloride Chlorhexidine Chlortetracycline Clotrimazole Cetylpyridinium chloride Domiphen bromide Doxycycline Eugenol Hexetidine Hydrogen peroxide Mepartricin Metronidazole Miconazole Minocycline Natamycin Neomycin Oxyquinoline Polynoxylin Sodium perborate Tetracycline Tibezonium iodide
Corticosteroids (Glucocorticoids)	Dexamethasone Hydrocortisone Triamcinolone
Other	Amlexanox Acetylsalicylic acid Becaplermin Benzydamine Epinephrine/Adrenalone

Clinical data

Routes of administration	Topical
ATC code	A01AB05 ( WHO ) D01AE05 ( WHO )
Identifiers
IUPAC name (poly) methylene-N,N'-bis(hydroxymethyl)urea
CAS Number	9011-05-6 ^Y
ChemSpider	none
UNII	E18NBG5EEY
KEGG	D07067
CompTox Dashboard (EPA)	DTXSID10905739 DTXSID00891874, DTXSID10905739
ECHA InfoCard	100.108.096
Chemical and physical data
Formula	(C₄H₈N₂O₃)_n
(verify)