RNF32

RNF32
Identifiers
Aliases	RNF32 , FKSG33, HSD15, LMBR2, ring finger protein 32
External IDs	OMIM: 610241; MGI: 1861747; HomoloGene: 10986; GeneCards: RNF32; OMA:RNF32 - orthologs
Gene location (Human) Chr. Chromosome 7 (human) [1] Band 7q36.3 Start 156,640,281 bp [1] End 156,677,130 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5 B1|5 14.78 cM Start 29,400,990 bp [2] End 29,433,455 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis sperm testicle bronchial epithelial cell C1 segment right uterine tube gonad islet of Langerhans left adrenal cortex Top expressed in spermatocyte spermatid seminiferous tubule interventricular septum genital tubercle zygote secondary oocyte primary oocyte urethra female urethra More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 140545 56874 Ensembl ENSG00000105982 ENSMUSG00000029130 UniProt Q9H0A6 Q9JIT1 RefSeq (mRNA) NM_001184996 NM_001184997 NM_001308273 NM_001308274 NM_030936 NM_001289757 NM_021470 RefSeq (protein) NP_001171925 NP_001171926 NP_001295202 NP_001295203 NP_112198 NP_001276686 NP_067445 Location (UCSC) Chr 7: 156.64 – 156.68 Mb Chr 5: 29.4 – 29.43 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RING finger protein 32 is a protein that in humans is encoded by the RNF32 gene. ^{[5] [6]}

The protein encoded by this gene contains two RING ring finger motifs. RING finger motifs are present in a variety of functionally distinct proteins and are known to be involved in protein-DNA or protein-protein interactions. This gene was found to be expressed during spermatogenesis, most likely in spermatocytes and/or in spermatids. Several alternatively spliced transcript variants exist, but their full length natures are not clear. ^[6]

See also

• RING finger domain

References

1. GRCh38: Ensembl release 89: ENSG00000105982 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000029130 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. van Baren MJ, van der Linde HC, Breedveld GJ, Baarends WM, Rizzu P, de Graaff E, Oostra BA, Heutink P (Mar 2002). "A double RING-H2 domain in RNF32, a gene expressed during sperm formation". Biochem Biophys Res Commun. 292 (1): 58–65. doi:10.1006/bbrc.2002.6612. PMID   11890671.
6. "Entrez Gene: RNF32 ring finger protein 32".

Further reading

• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi: 10.1101/gr.8.11.1097 . PMID   9847074.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi: 10.1038/nature01782 . PMID   12853948.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.

External links

• RNF32+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)