RNF39

RNF39
Identifiers
Aliases	RNF39 , HZF, HZFW, LIRF, ring finger protein 39, FAP216
External IDs	OMIM: 607524; MGI: 2156378; HomoloGene: 11891; GeneCards: RNF39; OMA:RNF39 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p22.1 Start 30,070,266 bp [1] End 30,075,849 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 B1 Start 37,253,810 bp [2] End 37,258,878 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen skin of leg minor salivary glands vagina olfactory zone of nasal mucosa prostate right uterine tube testicle body of stomach ectocervix Top expressed in skin of abdomen lip esophagus skin of external ear skin of back conjunctival fornix hair follicle decidua gastrula right lung lobe More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding Cellular component cytoplasm cellular component Biological process biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 80352 386454 Ensembl ENSG00000230467 ENSG00000206500 ENSG00000204618 ENSG00000237733 ENSG00000227171 ENSG00000235022 ENSG00000236967 ENSG00000230332 ENSMUSG00000036492 UniProt Q9H2S5 n/a RefSeq (mRNA) NM_170770 NM_025236 NM_170769 NM_001099632 RefSeq (protein) NP_079512 NP_739575 n/a Location (UCSC) Chr 6: 30.07 – 30.08 Mb Chr 17: 37.25 – 37.26 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RING finger protein 39 is a protein that in humans is encoded by the RNF39 gene. ^{[5] [6] [7]}

This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Alternative splicing results in three transcript variants encoding different isoforms. ^[7]

References

1. ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 GRCh38: Ensembl release 89: ENSG00000230467, ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036492 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Coriton O, Lepourcelet M, Hampe A, Galibert F, Mosser J (Dec 2000). "Transcriptional analysis of the 69-kb sequence centromeric to HLA-J: a dense and complex structure of five genes". Mamm Genome. 11 (12): 1127–31. doi:10.1007/s003350010213. PMID   11130983. S2CID   22881226.
6. Matsuo R, Asada A, Fujitani K, Inokuchi K (Nov 2001). "LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein". Biochem Biophys Res Commun. 289 (2): 479–84. doi:10.1006/bbrc.2001.5975. PMID   11716498.
7. "Entrez Gene: RNF39 ring finger protein 39".

Further reading

• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Orimo A, Yamagishi T, Tominaga N, et al. (2000). "Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC". Biochem. Biophys. Res. Commun. 276 (1): 45–51. doi:10.1006/bbrc.2000.3380. PMID   11006080.
• Hidaka M, Caruana G, Stanford WL, et al. (2000). "Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells". Mech. Dev. 90 (1): 3–15. doi: 10.1016/S0925-4773(99)00234-8 . PMID   10585558. S2CID   673064.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID   8889548.