SFRS6

Last updated
SRSF6
Identifiers
Aliases SRSF6 , B52, HEL-S-91, SFRS6, SRP55, serine/arginine-rich splicing factor 6, serine and arginine rich splicing factor 6
External IDs OMIM: 601944; MGI: 1915246; HomoloGene: 110783; GeneCards: SRSF6; OMA:SRSF6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006275

NM_026499

RefSeq (protein)

NP_006266

NP_080775

Location (UCSC) Chr 20: 43.46 – 43.47 Mb Chr 2: 162.77 – 162.78 Mb
PubMed search [3] [4]
Wikidata
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Splicing factor, arginine/serine-rich 6 is a protein that in humans is encoded by the SFRS6 gene. [5] [6]

Contents

Function

The protein encoded by this gene is involved in mRNA splicing and may play a role in site selection in alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000124193 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000016921 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Screaton GR, Cáceres JF, Mayeda A, Bell MV, Plebanski M, Jackson DG, Bell JI, Krainer AR (September 1995). "Identification and characterization of three members of the human SR family of pre-mRNA splicing factors". The EMBO Journal. 14 (17): 4336–49. doi:10.1002/j.1460-2075.1995.tb00108.x. PMC   394518 . PMID   7556075.
  6. 1 2 "Entrez Gene: SFRS6 splicing factor, arginine/serine-rich 6".

Further reading