SS18L1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | SS18L1 , CREST, LP2261, nBAF chromatin remodeling complex subunit, SS18L1 subunit of BAF chromatin remodeling complex, SMARCL2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 606472 MGI: 2444061 HomoloGene: 9191 GeneCards: SS18L1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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SS18-like protein 1 is a protein that in humans is encoded by the SS18L1 gene. [5]
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90% of cases have a recurrent and specific chromosomal translocation, t(X;18)(p11.2;q11.2), in which the 5-prime end of the SS18 gene is fused in-frame to the 3-prime end of the SSX1, SSX2, or SSX4 gene. The SS18L1 gene is homologous to SS18. [5]
SS18L1 has been shown to interact with CREB-binding protein. [6] Biochemical pull down assays reveal SS18L1 to interact with several components of the human SWI/SNF chromatin remodeling complex. [7]
A synovial sarcoma is a rare form of cancer which occurs primarily in the extremities of the arms or legs, often in proximity to joint capsules and tendon sheaths. It is a type of soft-tissue sarcoma.
Proto-oncogene tyrosine-protein kinase Yes is a non-receptor tyrosine kinase that in humans is encoded by the YES1 gene.
Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.
Programmed cell death 6-interacting protein also known as ALIX is a protein that in humans is encoded by the PDCD6IP gene.
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 is a protein that in humans is encoded by the SMARCA5 gene.
AT-rich interactive domain-containing protein 1A is a protein that in humans is encoded by the ARID1A gene.
SWI/SNF complex subunit SMARCC1 is a protein that in humans is encoded by the SMARCC1 gene.
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 is a protein that in humans is encoded by the SMARCE1 gene.
SWI/SNF complex subunit SMARCC2 is a protein that in humans is encoded by the SMARCC2 gene.
Protein SSX2 is a protein that in humans is encoded by the SSX2 gene.
Protein SSXT is a protein that in humans is encoded by the SS18 gene.
Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene.
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 is a protein that in humans is encoded by the SMARCD1 gene.
Nuclear protein 1 is a protein that in humans is encoded by the NUPR1 gene.
Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin is a protein that in humans is encoded by the CACNG2 gene.
Protein SSX1 is a protein that in humans is encoded by the SSX1 gene.
Afadin- and alpha-actinin-binding protein is a protein that in humans is encoded by the SSX2IP gene. It has been shown that it functions together with WDR8 in centrosome maturation, ensuring proper spindle length and orientation. The SSX2IP-WDR8 complex additionally promotes ciliary vesicle docking during ciliogenesis.
Protein SSX4 is a protein that in humans is encoded by the SSX4 gene.
Protein AF-10 is a protein that in humans is encoded by the MLLT10 gene.
Protein SSX5 is a protein that in humans is encoded by the SSX5 gene.