| Sargassum siliquastrum | |
|---|---|
 | |
Scientific classification  | |
| Clade: | SAR |
| Phylum: | Ochrophyta |
| Class: | Phaeophyceae |
| Order: | Fucales |
| Family: | Sargassaceae |
| Genus: | Sargassum |
| Species: | S. siliquastrum |
| Binomial name | |
| Sargassum siliquastrum (Mertens ex Turner) C.Agardh, 1820 | |
| Subspecies | |
| |
| Synonyms | |
Sargassum tortile (C.Agardh) C.Agardh, 1820 | |
Sargassum siliquastrum is a brown alga species in the genus Sargassum .
Sargachromanols are bio-active isolates of S. siliquastrum. It has anti-inflammatory effect. [1]
Nonsteroidal anti-inflammatory drugs (NSAIDs) are members of a drug class that reduces pain, decreases fever, prevents blood clots, and in higher doses, decreases inflammation. Side effects depend on the specific drug but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack, and kidney disease.
The brown algae, comprising the class Phaeophyceae, are a large group of multicellular algae, including many seaweeds located in colder waters within the Northern Hemisphere. Most brown algae live in marine environments, where they play an important role both as food and as a potential habitat. For instance, Macrocystis, a kelp of the order Laminariales, may reach 60 m (200 ft) in length and forms prominent underwater kelp forests. Kelp forests like these contain a high level of biodiversity. Another example is Sargassum, which creates unique floating mats of seaweed in the tropical waters of the Sargasso Sea that serve as the habitats for many species. Many brown algae, such as members of the order Fucales, commonly grow along rocky seashores. Some members of the class, such as kelps, are used by humans as food.
Cercis is a genus of about 10 species in the subfamily Cercidoideae of the pea family Fabaceae, native to warm temperate regions. It contains small deciduous trees or large shrubs commonly known as redbuds. They are characterised by simple, rounded to heart-shaped leaves and pinkish-red flowers borne in the early spring on bare leafless shoots, on both branches and trunk ("cauliflory"). Cercis is derived from the Greek word κερκις (kerkis) meaning "weaver's shuttle", which was applied by Theophrastus to C. siliquastrum.
Naproxen, sold under the brand name Aleve among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, and fever. It is taken orally. It is available in immediate and delayed release formulations. Onset of effects is within an hour and last for up to twelve hours.
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebrate animal cell. The name "glucocorticoid" is a portmanteau and is composed from its role in regulation of glucose metabolism, synthesis in the adrenal cortex, and its steroidal structure.
Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system to block pain signaling to the brain.
Sargassum is a genus of brown macroalgae (seaweed) in the order Fucales. Numerous species are distributed throughout the temperate and tropical oceans of the world, where they generally inhabit shallow water and coral reefs, and the genus is widely known for its planktonic (free-floating) species. Most species within the class Phaeophyceae are predominantly cold-water organisms that benefit from nutrients upwelling, but the genus Sargassum appears to be an exception. Any number of the normally benthic species may take on a planktonic, often pelagic existence after being removed from reefs during rough weather; however, two species have become holopelagic—reproducing vegetatively and never attaching to the seafloor during their lifecycles. The Atlantic Ocean's Sargasso Sea was named after the algae, as it hosts a large amount of Sargassum.
Carprofen, marketed under many brand names worldwide, is a nonsteroidal anti-inflammatory drug (NSAID) that veterinarians prescribe as a supportive treatment for various conditions in animals. It provides day-to-day treatment for pain and inflammation from various kinds of joint pain as well as post-operative pain. Carprofen reduces inflammation by inhibition of COX-1 and COX-2; its specificity for COX-2 varies from species to species.
Curcuma amada, or mango ginger is a plant of the ginger family Zingiberaceae and is closely related to turmeric. The rhizomes are very similar to common ginger but lack its pungency, and instead have a raw mango flavour. They are used in making pickles in south India and chutneys in north India. The taxonomy of the species is a subject of some confusion as some authorities have considered the name C. mangga as identical while others describe it as a distinct species with C. mangga being found in southern India while C. amada is of east Indian origin. Mango-ginger is a popular spice and vegetable due to its rich flavor, which is described as sweet with subtle earthy floral and pepper overtones and similar to that of raw mango. It is a delicious addition to salads and stir fries. It is used in South Asian and Southeast Asian as well as Far East Asian cuisines.
Weissella is a genus of gram-positive bacteria, placed within the family Leuconostocaceae, and formerly considered species of the Leuconostoc paramesenteroides group. The morphology of Weissella species varies from spherical or lenticular cells to irregular rods. Several strains of Weissella cibaria and Weissella confusa have shown the probiotic potential. In particular, the cell-free culture supernatant of Weissella confusa shows various beneficial characteristics such as antibacterial potential and anti-inflammatory efficiency. However, there are few strains of W. confusa was also found as an opportunistic bacteria. On the other, several studies have also done the safety assessment of the bacterial species, indicating it's probiotic potential. In addition, the Senate Commission on Food Safety has also validated the usage of W. confusa in the food.
Ajulemic acid (AB-III-56, HU-239, IP-751, CPL 7075, CT-3, JBT-101, Anabasum, Resunab) is a synthetic cannabinoid derivative of the THC metabolite 11-nor-9-carboxy-THC that shows anti-fibrotic and anti-inflammatory effects in pre-clinical studies without causing a subjective "high". It is being developed for the treatment of inflammatory and fibrotic conditions such as systemic sclerosis, dermatomyositis and cystic fibrosis. It does not share the anti-emetic effects of some other cannabinoids, but may be useful for treating chronic inflammatory conditions where inflammation fails to resolve. Side effects include dry mouth, tiredness, and dizziness. The mechanism of action is through activation of the CB2 receptor leading to production of specialized proresolving eicosanoids such as lipoxin A4 and Prostaglandin J2. Studies in animals at doses up to 40 mg/kg show minimal psychoactivity of ajulemic acid, compared to that produced by tetrahydrocannabinol. A composition of ajulemic acid named Lenabasum (formerly Anabasum, Resunab) is being developed by Corbus Pharmaceuticals (formerly JB Therapeutics) for the treatment of orphan chronic life-threatening inflammatory diseases.
Cercis siliquastrum is a small deciduous tree from Southern Europe and Western Asia which is noted for its prolific display of deep pink flowers in spring.
Meclofenamic acid is a drug used for joint, muscular pain, arthritis and dysmenorrhea. It is a member of the anthranilic acid derivatives class of nonsteroidal anti-inflammatory drugs (NSAIDs) and was approved by the US FDA in 1980. Like other members of the class, it is a cyclooxygenase (COX) inhibitor, preventing the formation of prostaglandins.
Benoxaprofen, also known as Benoxaphen, is a chemical compound with the formula C16H12ClNO3. It is a nonsteroidal anti-inflammatory drug (NSAID) and was marketed under the brand name Oraflex in the United States and as Opren in Europe by Eli Lilly and Company. Lilly suspended sales of Oraflex in 1982 after reports from the British government and the U.S. Food and Drug Administration (FDA) of adverse effects and deaths linked to the drug.
Sigesbeckia is a genus of annual plants in the aster family. St. Paul's wort is a common name for some of the species. Sigesbeckia is widely distributed and has been traditionally used for the management of chronic diseases, including arthritis. Based on phytochemical studies, the main chemicals in Sigesbeckia include flavonoids, sesquiterpenoids, diterpenoids, triterpenoids, and sterols. Kaurane-type and pimarane-type diterpenoids, including siegeskaurolic acid, kirenol, and sesquiterpene lactone are the main bio-active molecules in Sigesbeckia.
Sargassum muticum, commonly known as Japanese wireweed, is a large brown seaweed of the genus Sargassum. It is an invasive seaweed with high growth rate. It has an efficient dispersion thanks to its floats.
Famprofazone is a nonsteroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan. It has analgesic, anti-inflammatory, and antipyretic effects. Famprofazone has been known to produce methamphetamine as an active metabolite, with 15-20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing positives on drug tests for amphetamines.
Sargachromanols are a group of related chemical compounds isolated from the brown alga Sargassum siliquastrum. At least 20 members of the class have been identified, named sargachromanol A through T. Sargachromanol G has in vitro anti-inflammatory effects in isolated mouse macrophage cells.
Sargassum horneri is a species of brown macroalgae that is common along the coast of Japan and Korea. It is an annual algae which has a varying fertile season along the coast. In Wakasa Bay it began to grow in early autumn through winter, becoming matured in Spring, when the sea water temperature was 11.6–15.2 °C (53–59 °F) in average. Also called "devil weed", this species has invaded the Eastern Pacific, beginning in Baja California and advancing north along the California coastline.
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