| Sodalis glossinidius | |
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| Species: | S. glossinidius Dale and Maudlin 1999 |
Sodalis glossinidius is a species of bacteria, the type and only species of its genus. It is a microaerophilic secondary endosymbiont of the tsetse fly. Strain M1T is the type strain. [1] Sodalis glossinidius is the only gammaproteobacterial insect symbiont to be cultured and thus amenable to genetic modification, suggesting that it could be used as part of a control strategy by vectoring antitrypanosome genes. The organism may increase the susceptibility of tsetse flies to trypanosomes. [2]
The genome of S.glossinidius spans 4.17 MB and encodes 2,431 protein-coding genes plus 1,501 pseudogenes. It is thus almost as large as that of E. coli (~4,100 genes). However, the number of genes encoding metabolic proteins is twice as large in E. coli, indicating that Sodalis has already a much reduced metabolic capacity. [3]
Despite gene erosion and pseudogene multiplication in a genome of Sodalis glossinidius, [4] its pseudogenes remain actively transcribed. [5]
S. glossinidius is itself host to a prophage discovered by Clark et al. 2007. [6]
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