External links
Sourav Bhattacharjee publications indexed by Google Scholar
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Sourav Bhattacharjee | |
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| Born | September 16, 1978 |
| Nationality | Dutch |
| Academic background | |
| Education | MBBS, Medical College Kolkata MSc (Biomolecular Sciences), VU Amsterdam PhD, Wageningen University |
| Alma mater | Medical College Kolkata Vrije Universiteit Amsterdam Wageningen University |
| Doctoral advisor | Han Zuilhof; Gerrit Alink; Ivonne MCM Rietjens; Antonius TM Marcelis |
| Academic work | |
| Institutions | University College Dublin |
Sourav Bhattacharjee is a Dutch biomedical scientist and anatomist of Indian origin. He is a Professor in the Veterinary Biosciences section at the School of Veterinary Medicine,University College Dublin. [1]
Bhattacharjee is known for his work on comparative anatomy,biomedical imaging,and translational drug delivery systems. His works have been published in academic journals such as Journal of Controlled Release , Nanoscale , Small , Journal of Anatomy ,and Annals of Anatomy . [2] Additionally,he edited the ‘’Special Issue on Biomedical Imaging in Comparative Anatomy’’in the Journal of Anatomy. [3] He also co-invented an oral delivery system wherein he described methods to create stabilized silica-coated sub-micron particles of proteins or peptides,including GLP-1 agonists and insulin,using a basic compound,zinc,and orthosilicic acid. [4] Moreover,he was ranked among the top 2% of scientists by Elsevier for five consecutive years,from 2020 to 2024. [5] [6]
Bhattacharjee is a fellow of the Royal Asiatic Society. Moreover,he is an editorial board member of several journals,including Nature Scientific Reports . [7]
Bhattacharjee completed his Bachelor of Medicine and Surgery (MBBS) from Medical College Kolkata (India) in 2004,followed by an MSc in Biomolecular Sciences in 2008 from the Vrije Universiteit Amsterdam (Netherlands). Later in 2012,he obtained his PhD from Wageningen University in the Netherlands. [1]
Bhattacharjee briefly served as a Residential House Surgeon at the Medical College Kolkata (India) in 2004. He also worked as a Student Assistant at the Lab of Organic Chemistry in 2008. From September 2012 to September 2013,he was a Post-Doctoral Researcher in the BIOS Lab-on-a-Chip group at the University of Twente (Netherlands). Between 2014 and 2016,he served as a Post-Doctoral Research Fellow at the School of Veterinary Medicine and the Conway Institute,University College Dublin. Additionally,between 2017 and 2019,he also served as an Honorary Demonstrator in Anatomy in the School of Medicine at Imperial College London (UK). Moreover,since 2016,he has been serving as an Assistant Professor in Veterinary Biosciences at the School of Veterinary Medicine,University College Dublin. [1]
Bhattacharjee is an active member of the Anatomical Society and has represented the society on various occasions,including initiatives to promote careers in anatomy [8] and participation in Anatomical Society conferences. He has delivered invited and keynote lectures internationally,with engagements in countries such as India,Indonesia,Spain, [9] and South Korea. [10] He has also been interviewed by academic journals in recognition of his expertise in nanomedicine. [11] [12] Moreover,in 2024,he presented seminars on tissue autofluorescence and oral insulin delivery at the University of Tartu and the Estonian University of Life Sciences in Estonia. [13] [14]
Bhattacharjee’s 2009 paper investigated the cytotoxicity of silicon nanoparticles with different surface functionalizations (amine,azide,carboxylic acid),imparting various surface charges,showing that positively charged silicon nanoparticles were more cytotoxic in vitro compared to the negatively charged ones,with serum presence influencing the toxicity. [15] Later,he examined how silicon nanoparticle surface charge affected cytotoxicity in macrophages,highlighting oxidative stress,mitochondrial involvement,and reactive oxygen species (ROS) production as key mechanisms of toxicity,with antioxidants providing protective effects. [16] Two years later,in 2012,he studied the effects of polymer nanoparticles' size and surface charge on cellular uptake,cytotoxicity,and the mechanisms of mitochondrial damage,reactive oxygen species production,and oxidative stress in different cell types. [17] In 2013,he investigated and compared the cytotoxicity of silicon and germanium nanoparticles,highlighting the impact of surface coatings,size,and doping on toxicity,particularly through mitochondrial dysfunction,with implications for bioimaging and biomedical applications. [18] In the same year,he explored the synthesis,cytotoxicity,cellular uptake,and interactions of polymeric nanoparticles with varying surface charges (cationic and anionic),emphasizing how surface charge and steric shielding of cationic charge influenced nanoparticle behavior and cytotoxicity under biological ambience. [19]
Subsequently,in 2014,Bhattacharjee investigated how surface charge and size of polystyrene nanoparticles affected cytotoxicity,focusing on oxidative stress and membrane disturbances as key mechanisms,particularly for cationic nanoparticles in macrophage cells. [20] His 2016 work reviewed dynamic light scattering and zeta potential techniques for nanoparticle characterization in drug delivery,explaining principles,challenges,and practical tips to help non-experts obtain reliable,relevant measurements. [21] Additionally,in 2017,he investigated how particle size,surface charge,and methyl-PEGylation affected the transport and interaction of silica nanoparticles with porcine jejunal mucus,providing insights for designing oral nanomedicines with improved mucopermeability. [22] In 2019,he edited the book Principles of Nanomedicine. The book explored nanomedicine,covering its history,fundamental properties of nanoscale materials,and applications in drug delivery,sensing,and imaging. [23] Later in 2020,he studied how ionic strength,pH,salt valency,and detergents affected the zeta potential and colloidal stability of extracellular vesicles derived from human choriocarcinoma JAr cells. [24] In the same year,he addressed burst release in drug delivery from nanocarriers,explored its causes,mathematical models,current mitigation techniques,and future directions for improving sustained release and translation into clinical applications. [25]
In 2023,Bhattacharjee authored a book chapter in Microscopy Techniques for Biomedical Education and Healthcare Practice,wherein he explored advanced microscopy and particle tracking techniques for studying cellular dynamics,focusing on nanoscale processes,biomedical applications,and the development of nanomedicines,while critiquing tracking software and future challenges. [26] More recently in 2024,he explored using machine learning on radiomics data from CT scans to predict grading and staging of upper tract urothelial carcinoma,offering potential for earlier,more accurate diagnoses compared to traditional methods. [27] Additionally,he also developed a predictive model combining radiomics from CT urograms and clinical data to accurately forecast survival and recurrence in UTUC patients,showing improved prognostic performance and achieving statistical significance in diagnosis. [28]
Directing his research efforts towards anatomy,Bhattacharjee examined the historical integration of humanistic values in anatomy,highlighting ethical challenges,legal responses,and lessons from past atrocities,shaping modern anatomical practices and promoting humane treatment in medicine. [29] Moreover,he also examined historical public dissections,highlighting their spiritual and societal roots,traced their decline due to ethical lapses,and advocated for renewed societal engagement through spiritually guided anatomical practices. [30] Among other things,he has worked on incorporating One Health principles into anatomy education and research,focusing on the relationships among human,animal,and environmental health. [31] This work examined how these interconnections can inform understandings of health and disease. Additionally,he is affiliated with the UCD One Health Centre and has published on topics related to One Health. [32]
{{cite journal}}: CS1 maint: DOI inactive as of July 2025 (link)Sourav Bhattacharjee publications indexed by Google Scholar
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