Sulfacetamide/sulfur

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Sulfacetamide/sulfur
Combination of
Sulfacetamide Sulfonamide antibacterial
Sulfur (pharmacy) Keratolytic
Clinical data
AHFS/Drugs.com Multum Consumer Information
License data
Routes of
administration 		Topical
ATC code
Legal status
Legal status
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The drug combination sulfacetamide/sulfur is a topical acne medication [1] manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar. It combines sodium sulfacetamide, a sulfonamide antibiotic, and sulfur, a keratolytic agent. [2] It is available in four formulations: as a cleansing cloth, cleanser, topical suspension, and as a facial mask. The sulfacetamide inhibits the growth of the bacterium Cutibacterium acnes that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores. [3]

In 2023, it was the 311th most commonly prescribed medication in the United States, with more than 200,000 prescriptions. [4]

References

  1. ↑ Del Rosso JQ (January 2004). "Evaluating the role of topical therapies in the management of rosacea: focus on combination sodium sulfacetamide and sulfur formulations". Cutis. 73 (1 Suppl): 29–33. PMID   14959943.
  2. ↑ "Plexion (sodium sulfacetamide 10% and sulfur 5%)". Medicis Inc. Retrieved 2 December 2008.
  3. ↑ "Plexion Prescribing information" (PDF). Medicis. Archived from the original (PDF) on 20 September 2009. Retrieved 2 December 2008.
  4. ↑ "Sulfacetamide; Sulfur Drug Usage Statistics, United States, 2013 - 2023". ClinCalc. Retrieved 21 August 2025.


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