TRIM9

Last updated
TRIM9
Protein TRIM9 PDB 2db8.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TRIM9 , RNF91, SPRING, tripartite motif containing 9
External IDs OMIM: 606555; MGI: 2137354; HomoloGene: 9045; GeneCards: TRIM9; OMA:TRIM9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015163
NM_052978

RefSeq (protein)

NP_055978
NP_443210

Location (UCSC) Chr 14: 50.98 – 51.1 Mb Chr 12: 70.29 – 70.39 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene. [5] [6] [7]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms. [7]

Interactions

TRIM9 has been shown to interact with SNAP-25. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000100505 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021071 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC   125245 . PMID   11331580.
  6. 1 2 Li Y, Chin LS, Weigel C, Li L (Oct 2001). "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis". J Biol Chem. 276 (44): 40824–33. doi: 10.1074/jbc.M106141200 . PMID   11524423.
  7. 1 2 "Entrez Gene: TRIM9 tripartite motif-containing 9".

Further reading