TXNL4B

TXNL4B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XBS, 3GIX, 4IN0
Identifiers
Aliases	TXNL4B , DLP, Dim2, thioredoxin like 4B
External IDs	OMIM: 617722 MGI: 2443724 HomoloGene: 9880 GeneCards: TXNL4B
Gene location (Human)
Chr.	Chromosome 16 (human)
End	72,094,431 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	110,300,683 bp
RNA expression pattern
	Top expressed in
	internal globus pallidus; ; monocyte; ; optic nerve; ; pancreatic ductal cell; ; right lobe of liver; ; endothelial cell; ; secondary oocyte; ; tibial nerve; ; blood; ; body of pancreas;
	Top expressed in
	spermatid; ; spermatocyte; ; otolith organ; ; utricle; ; seminiferous tubule; ; secondary oocyte; ; submandibular gland; ; substantia nigra; ; left lobe of liver; ; neural tube;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	U5 snRNP ; nucleus ; nucleoplasm ; cytosol ; spliceosomal complex ; U4/U6 x U5 tri-snRNP complex ;
Biological process	mRNA splicing, via spliceosome ; cell cycle ; mRNA processing ; spliceosomal complex assembly ; RNA splicing ;
	Sources:Amigo / QuickGO
Orthologs
	54957
	234723
	ENSG00000140830
	ENSMUSG00000031723
	Q9NX01
	Q8BUH1
	NM_017853 ; NM_001142317 ; NM_001142318 ; NM_001324354 ; NM_001324355 Contents Interactions ; References ; Further reading ;
	NM_175646
	NP_001135789 ; NP_001135790 ; NP_001311283 ; NP_001311284 ; NP_060323
	NP_783577
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 29, 2022

Thioredoxin-like protein 4B is a protein that in humans is encoded by the TXNL4B gene.^[5]^[6]

Interactions

TXNL4B has been shown to interact with PRPF6.^[5]

Related Research Articles

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TOM1-like protein 1 is a protein that in humans is encoded by the TOM1L1 gene.

28S ribosomal protein S7, mitochondrial is a protein that in humans is encoded by the MRPS7 gene.

Vacuolar protein sorting-associated protein 11 homolog is a protein that in humans is encoded by the VPS11 gene.

39S ribosomal protein L11, mitochondrial is a protein that in humans is encoded by the MRPL11 gene.

28S ribosomal protein S28, mitochondrial is a protein that in humans is encoded by the MRPS28 gene.

39S ribosomal protein L30, mitochondrial is a protein that in humans is encoded by the MRPL30 gene.

39S ribosomal protein L39, mitochondrial is a protein that in humans is encoded by the MRPL39 gene.

Nucleolar protein 8 is a protein that in humans is encoded by the NOL8 gene.

28S ribosomal protein S11, mitochondrial is a protein that in humans is encoded by the MRPS11 gene.

Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene.

Thioredoxin-like protein 4A is a protein that is encoded by the TXNL4A gene in humans.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000140830 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031723 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 Sun X, Zhang H, Wang D, Ma D, Shen Y, Shang Y (Jul 2004). "DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression". J Biol Chem. 279 (31): 32839–47. doi: 10.1074/jbc.M402522200 . PMID 15161931.
↑ "Entrez Gene: TXNL4B thioredoxin-like 4B".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Zhang YZ, Gould KL, Dunbrack RL JR, Cheng H, Roder H, Golemis EA (2001). "The evolutionarily conserved Dim1 protein defines a novel branch of the thioredoxin fold superfamily" (PDF). Physiol. Genomics. 1 (3): 109–18. doi:10.1152/physiolgenomics.1999.1.3.109. PMID 11015569. S2CID 16086223.
Schelling P, Claus MT, Johner R, Marquez VE, Schulz GE, Scapozza L (2004). "Biochemical and structural characterization of (South)-methanocarbathymidine that specifically inhibits growth of herpes simplex virus type 1 thymidine kinase-transduced osteosarcoma cells". J. Biol. Chem. 279 (31): 32832–8. doi: 10.1074/jbc.M313343200 . PMID 15163659.
Simeoni F, Arvai A, Bello P, Gondeau C, Hopfner KP, Neyroz P, Heitz F, Tainer J, Divita G (2005). "Biochemical characterization and crystal structure of a Dim1 family associated protein: Dim2". Biochemistry. 44 (36): 11997–2008. doi:10.1021/bi050427o. PMID 16142897.
Jin T, Howard AJ, Golemis EA, Wang Y, Zhang YZ (2006). "Overproduction, purification, crystallization and preliminary X-ray diffraction studies of the human spliceosomal protein TXNL4B". Acta Crystallographica Section F. 61 (Pt 3): 282–4. doi:10.1107/S1744309105002861. PMC 1952293 . PMID 16511018.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000140830 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031723 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15161931-5] 1 2 Sun X, Zhang H, Wang D, Ma D, Shen Y, Shang Y (Jul 2004). "DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression". J Biol Chem. 279 (31): 32839–47. doi: 10.1074/jbc.M402522200 . PMID 15161931.

[entrez-6] "Entrez Gene: TXNL4B thioredoxin-like 4B".

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TXNL4B

Contents

Interactions

Related Research Articles

References

Further reading