Lauderdale County is a county located on the western edge of the U.S. state of Tennessee, with its border the Mississippi River. As of the 2020 census, the population was 25,143. Its county seat is Ripley. Since the antebellum years, it has been developed for cotton as a major commodity crop.
U.S. Route 411 (US 411) is an alternate parallel-highway associated with US 11. It extends for about 309.7 miles (498.4 km) from US 78 in Leeds, Alabama, to US 25W/US 70 in Newport, Tennessee. US 411 travels through northeastern Alabama, northwestern Georgia, and southeastern Tennessee. It is signed north-south, as with most highways that have odd numbers, but the route runs primarily in a northeast-southwest direction, and covers a more east-west mileage than it does north-south. Notable towns and cities along its route include Gadsden, Alabama; Rome, Georgia; Cartersville, Georgia; Maryville, Tennessee; Sevierville, Tennessee, and Newport, Tennessee.
State Route 22 is a 172.8-mile long (278.1 km) south-to-north state highway in the western part of Tennessee, United States. It begins at the Mississippi state line in McNairy County, where the roadway continues as Mississippi Highway 2. It ends at the Kentucky state line in Lake County, when it crosses into the Kentucky Bend, a detached portion of Fulton County, Kentucky. The monument for the 1862 Battle of Island Number Ten in the American Civil War is located on SR 22, about 3 mi (4.8 km) north of Tiptonville.
State Route 66 is a state-maintained highway in eastern Tennessee, including a six-lane divided highway known as Winfield Dunn Parkway in Sevier County, a four-lane expressway in Hamblen and Jefferson counties and a two-lane rural collector through mountainous terrain continuing to the northeast terminus in Hancock County.
State Route 62 is a 87.5-mile-long (140.8 km) west-to-east highway in the U.S. state of Tennessee. It is designated as a primary route except for the short segment between SR 169 and its eastern terminus, which is secondary.
State Route 19 or the Tina Turner Highway is a state highway in Haywood and Lauderdale counties in Tennessee, United States. State Route 19 is 42.81 mi (69 km) long.
Golddust is a rural unincorporated community in Lauderdale County, Tennessee, United States. It is located on the banks of the Mississippi River. Golddust is one of the earliest European-American settlements in Lauderdale County.
State Route 20 (SR 20) is a 143.04-mile (230.20 km) long east–west primary state highway that begins in Dyersburg and ending near Summertown. SR 20 is unsigned and concurrent with U.S. Route 412 (US 412) for its entire length, except for a short section between Hohenwald and Summertown. Along its route, SR 20 traverses parts of both Middle Tennessee and West Tennessee.
U.S. Route 70 Alternate is a 61.7-mile-long (99.3 km) alternate route to US 70 between Brownsville, and Huntingdon in West Tennessee. Signage along this route, and on most maps, show it as US 70A and not US 70 Alternate.
State Route 15 is a west–east route from Memphis to Monteagle. For much of its route it has an unsigned concurrency with U.S. Route 64. SR 15 does travel through the southern part of all 3 Grand Divisions of the state: West Tennessee, Middle Tennessee, and East Tennessee.
In Tennessee, U.S. Route 412 stretches for 181.93 miles (292.79 km) through the farmland of West Tennessee and the hills of Middle Tennessee, starting at the Missouri state line near Dyersburg and running to an interchange between I-65 and SR 99 in Columbia.
State Route 70 is a state-maintained highway in East Tennessee, beginning at the border with North Carolina in the midst of the Cherokee National Forest and the Great Smoky Mountains and ending at the Virginia border in the extremely rural and mountainous terrain of Hancock County.
Mississippi Highway 178 (MS 178), or simply "Old 78", is a 119.1-mile-long (191.7 km) east-west state highway across the northern portion of the state of Mississippi. It is the former alignment of U.S. Route 78 (US 78), used from the 1940s until the 1990s. With the exception of a break at the Tennessee-Tombigbee Waterway in Fulton, MS 178 is a complete route from Memphis, Tennessee, to the Alabama state line.
State Route 32 is a state highway in East Tennessee. For most of its route, it is an unsigned companion route concurrent with U.S. Route 25E. The highway stretches 89 miles from the North Carolina state line to the Tennessee-Kentucky state line near the town of Cumberland Gap.
State Route 297 is a 62.0-mile-long (99.8 km) east–west secondary state highway in Middle and East Tennessee. It is the primary road in and out of Scott State Forest and Big South Fork National River and Recreation Area, where it is known as Leatherwood Ford Road.
State Route 339 is a 23.1 miles (37.2 km) long east-west state highway in the mountains of East Tennessee, connecting Cherokee Hills with Cosby. For the majority of its length, SR 339 is known as Jones Cove Road, but other short sections are known as Long Springs Road and Old Newport Highway.
State Route 129 is a 49.22-mile-long (79.21 km) east–west state highway in the hills of southern Middle Tennessee.
State Route 104 is a 114.43-mile-long east–west state highway in West Tennessee.
State Route 438 is a 41.0 miles (66.0 km) long east-west state highway in extreme western Middle Tennessee.
State Route 247 is a 26.4-mile-long (42.5 km) east–west state highway in Maury and Williamson counties of Middle Tennessee.
SR 207 at Fulton 
US 51 near Henning 
SR 209 at Henning
SR 19 near Brownsville 
