U.S. Highway 181 is a south–north U.S. Highway located entirely in the state of Texas. Both termini are at Interstate 37, the road that it mainly parallels to the east. US 181 begins in Corpus Christi, Texas at mile marker 0 to the south, through south-central Texas to just south of San Antonio to the north, for a total length of 137 miles (220 km).
U.S. Route 290 is an east–west U.S. Highway located entirely within the state of Texas. Its western terminus is at Interstate 10 southeast of Segovia, and its eastern terminus is at Interstate 610 in northwest Houston. It is the main highway between Houston and Austin and is a cutoff for travelers wanting to bypass San Antonio on Interstate 10. Throughout its length west of Austin, US 290 cuts across mountainous hills comprising the Texas Hill Country and the Edwards Plateau; between Austin and Houston, the highway then travels through gradually hilly grasslands and pine forests comprising the Gulf Coastal Plains.
State Highway 6 (SH 6) runs from the Red River, the Texas–Oklahoma state line, to northwest of Galveston, where it is known as the Old Galveston Highway. In Sugar Land and Missouri City, it is known as Alvin-Sugarland Road and runs perpendicular to Interstate 69/U.S. Highway 59 (I-69/US 59). In the Houston area, it runs north to Farm to Market Road 1960 (FM 1960), then northwest along US 290 to Hempstead, and south to Westheimer Road and Addicks, and is known as Addicks Satsuma Road. In the Bryan–College Station area, it is known as the Earl Rudder Freeway. In Hearne, it is known as Market Street. In Calvert, it is known as Main Street. For most of its length, SH 6 is not a limited-access road. In 1997, the Texas Legislature designated SH 6 as the Texas Korean War Veterans Memorial Highway.
State Highway 31 runs from U.S. 84 northeast of Waco via Corsicana, Athens, Tyler, Kilgore to U.S. 80 in Longview.
Loop 1604 is the outer highway loop encircling San Antonio, Texas, spanning approximately 95.6 miles (153.9 km). Originally constructed as a two-lane highway, the northern segment of the route, from US 90 in western San Antonio to Kitty Hawk Road in northeastern Bexar County, has been upgraded to a four-lane freeway. Loop 1604 is designated the Charles W. Anderson Loop in honor of former Bexar County Judge Charles W. Anderson, who died from cancer in 1964 after serving for 25 years.
State Highway 149 is a state highway that runs from Carthage to Longview in east Texas.
State Highway Loop 390 is a state highway loop that forms a partial beltway around Marshall, Texas.
There are currently three business routes of U.S. Route 83 in Texas that are designated and maintained by the Texas Department of Transportation (TxDOT). The business routes in the US state of Texas are traditionally short spurs or loops that connect the main route, in this case, U.S. Route 83 (US 83), to the center or commercial district of a city. The routes commonly follow the course of a decommissioned state highway, or the old course of the main route. Business routes are signed with the traditional US 83 highway shield, and with a small "business plate" placed above the marker. TxDOT regards business routes as official highways, and is responsible for the maintenance of the route.
I-20 / US 259 / SH 322 in Longview 
I-20 / FM 968 near Longview
