Thomas Platts-Mills

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Thomas Platts-Mills
Thomas Platts-Mills.jpg
Thomas Platts-Mills
Born (1941-11-22) 22 November 1941 (age 80)
Nationality British
Alma mater Balliol College, Oxford
St. Thomas' Hospital Medical School
London University
Johns Hopkins University
Awards Fellow of the Royal Society
Scientific career
Fields Allergy, Immunology
Institutions University of Virginia School of Medicine, Medical Research Council

Thomas Alexander Evelyn Platts-Mills, FRS (born 1941, Colchester) son of British member of parliament and barrister John Platts-Mills, is a British allergy researcher and director of the Division of Allergy and Clinical Immunology at the University of Virginia School of Medicine. [1] [2] [3] [4]

Contents

Platts-Mills was educated at University College London. He then went to Balliol College, Oxford and St. Thomas' Hospital Medical School, received his PhD from London University, and completed a fellowship at Johns Hopkins University under the tutelage of Kimishige Ishizaka. He became a member of the Royal College of Physicians in 1971.

From 1975 to 1982, he worked in Britain for the Medical Research Council. Since 1982 he has worked at the University of Virginia where he has been Professor of Medicine and Microbiology and, since 1993, head of the Division of Allergy and Clinical Immunology. He served as President of the American Academy of Allergy, Asthma, and Immunology (AAAAI) from March 2006 to March 2007.

Research

Since 1974, Platts-Mills has been active in research on allergic disease and has published more than 350 papers.

His research includes the first purification and publication of a dust mite allergen in 1978, the development of immunoassays for dust mite allergens, and the establishment that it is mite fecal particles which are inhaled. [5] Platts-Mills has researched the immune response to a range of allergens including those from pollens, dust mites, the fungus Trichophyton, and domestic cats.

Platts-Mills is credited with the discovery of the mammalian meat allergy, after he discovered in 2002 the link between alpha-gal allergy and Lone Star tick bites. [6]

Awards

In 2010, his research earned Platts-Mills election as a Fellow of the Royal Society, the first allergist to be named to this select group. [7]

Related Research Articles

Allergy Immune system response to a substance that most people tolerate well

Allergies, also known as allergic diseases, are a number of conditions caused by hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, a runny nose, shortness of breath, or swelling. Food intolerances and food poisoning are separate conditions.

Allergic rhinitis Human disease

Allergic rhinitis, of which the seasonal type is called hay fever, is a type of inflammation in the nose that occurs when the immune system overreacts to allergens in the air. Signs and symptoms include a runny or stuffy nose, sneezing, red, itchy, and watery eyes, and swelling around the eyes. The fluid from the nose is usually clear. Symptom onset is often within minutes following allergen exposure, and can affect sleep and the ability to work or study. Some people may develop symptoms only during specific times of the year, often as a result of pollen exposure. Many people with allergic rhinitis also have asthma, allergic conjunctivitis, or atopic dermatitis.

Allergen immunotherapy Medical treatment for environmental allergies

Allergen immunotherapy, also known as desensitization or hypo-sensitization, is a medical treatment for environmental allergies, such as insect bites, and asthma. Immunotherapy involves exposing people to larger and larger amounts of allergen in an attempt to change the immune system's response.

Hypoallergenic dog breed Type of dog

A hypoallergenic dog breed is a dog breed that is purportedly more compatible with allergic people than are other breeds. However, prominent allergen researchers have determined that there is no basis to the claims that certain breeds are hypoallergenic and, while allergen levels vary among individual dogs, the breed is not a significant factor.

Founded in 1943, the American Academy of Allergy, Asthma & Immunology (AAAAI) is a professional medical membership organization of nearly 6,800 allergist/immunologists and related professionals around the world with advanced training and experience in allergy, asthma and other immunologic diseases. The Academy is dedicated to the advancement of the knowledge and practice of allergy, asthma and immunology for optimal patient care.

The use of podiatry drills, in the absence of engineering controls and personal protective equipment, is an occupational hazard to the healthcare provider. Nail dust collected during foot care procedures performed in office settings has been found to contain keratin, keratin hydrolysates, microbial debris, and viable fungal elements, including dermatophytes and saprotrophs. Exposure to nail dust and the associated risk will vary with the policies and practices in place, the type of podiatry drill used, therapy technique, frequency of procedures, personal protective equipment utilized and the use of ventilation systems.

Pathophysiology of asthma Medical condition

Asthma is a common pulmonary condition defined by chronic inflammation of respiratory tubes, tightening of respiratory smooth muscle, and episodes of bronchoconstriction. The Centers for Disease Control and Prevention estimate that 1 in 11 children and 1 in 12 adults have asthma in the United States of America. According to the World Health Organization, asthma affects 235 million people worldwide. There are two major categories of asthma: allergic and non-allergic. The focus of this article will be allergic asthma. In both cases, bronchoconstriction is prominent.

Ruby Umesh Pawankar

Ruby Pawankar has been President of the World Allergy Organization (WAO), 2012 and 2013. She is the first Indian and first woman President of WAO, which was established in 1951. Currently she is Past President, WAO, President of the Asia Pacific Association of Allergy Asthma and Clinical Immunology (APAAACI) and Council Member of Collegium Internationale Allergolicum (CIA). She is Professor of Allergy, Department of Pediatrics at Nippon Medical School in Tokyo, Japan and Guest Professor at Showa University School of Medicine, Tokyo, Japan, Kyung Hee University School of Medicine, Seoul, Korea and St. John's Medical College, Bengaluru, India. She is a recipient of Pravasi Bharatiya Samman 2010 for excellence in medicine, from the President of India.

Laboratory animal allergy (LAA) is an occupational disease of laboratory animal technicians and scientists. It manifests as an allergic response to animal urine, specifically the major urinary proteins (Mups) of rodents, and can lead to the development of asthma. A study of 5641 workers in Japan who were exposed to laboratory animals found 23.1% had one or more allergic symptoms; globally the prevalence among at risk workers is estimated between 11 and 30% According to the National Institutes of Health, prevention of animal allergy depends on the control of allergens in the work environment. This involves a combination of measures to eliminate or control allergen exposure, including engineering controls, administrative controls, and personal protective equipment.

Peptidase 1 (mite)

Peptidase 1 (mite), also known as endopeptidase 1 (mite), is an enzyme found in various species of mites. This enzyme exhibits cysteine protease activity with broad endopeptidase specificity.

Alpha-gal allergy — or mammalian meat allergy (MMA) — is a type of meat allergy characterized by a delayed onset of symptoms after ingesting mammalian meat and resulting from past exposure to tick bites. It was first reported in 2002. Symptoms of the allergy include rash, hives, nausea or vomiting, difficulty breathing, drop in blood pressure, dizziness or faintness and severe stomach pain.

Kari Nadeau American Physician and scientist

Kari C. Nadeau is an American physician-scientist focused on allergy and asthma treatment at Stanford University School of Medicine. She is the Naddisy Family Foundation Professor of Allergy and the director of the Sean N Parker Center for Allergy Research at Stanford. Her team was among the first to show that high dimensional immunophenotyping of T cells involved in allergy could be used in therapies for patients. Her research has also shown that blocking antibodies in conjunction with allergen immunotherapy produced desensitization even in patients with up to five food allergens.

Oral mite anaphylaxis (OMA), also known as pancake syndrome, is a disease in which a person gets symptoms after eating food contaminated with particular mites. The disease name comes from reports of people becoming ill after eating pancakes made from contaminated wheat or corn (maize) flour.

HAL Allergy Group

HAL Allergy Group is a pharmaceutical company that develops, produces and sells products for allergy diagnostic and allergen immunotherapy (AIT). The research facilities and headquarters are located at the Leiden Bio Science Park, Netherlands.

Rice allergy is a type of food allergy. People allergic to rice react to some rice proteins after they eat rice or breathe in rice steam. Although some reactions might lead to severe health problems, doctors can diagnose rice allergy with many methods and help allergic people to avoid reactions.

Gail Ina Greenberg Shapiro was an American pediatric allergist based in Seattle. She was a faculty member at the University of Washington School of Medicine. In 2001, she became the first democratically elected president of the American Academy of Allergy, Asthma, and Immunology (AAAAI).

Suranjith Seneviratne is a doctor from Sri Lanka who practices in allergy and immunology.

Clare Margaret Lloyd is a Professor of Medicine and Vice Dean for Institutional Affairs at Imperial College London. She investigates allergic immunity in early life.

Giorgio Walter Canonica Italian allergist and pulmonologist

Giorgio Walter Canonica is an Italian allergist, pulmonologist and professor of Respiratory Medicine at Humanitas University, Milan, Italy and Director Personalized Medicine Asthma & Allergy Center at Humanitas Research Hospital IRCCS-Milano Italy since December 2016. He is known for his research work related to innovative treatment strategies for allergic diseases which includes biological response modifier in form of targeted immunotherapy with primary emphasis on sublingual immunotherapy (SLIT). He has served as Secretary General and President elect of World Allergy Organisation for six consecutive years and has served as president of the same organization during 2007–09. He is also the vice-president of INTERASMA.

References

  1. "PROFESSOR PLATTS-MILLS: CURRICULUM VITAE" (PDF). Food and Drug Administration .
  2. "AAAAI announcement". Archived from the original on August 17, 2007.
  3. Bio - University of Virginia
  4. "Royal Society Bio". Archived from the original on October 6, 2012.
  5. "Dr. Thomas A.E. Platts-Mills on Allergen Avoidance through Environmental Control | AchooAllergy.com". www.achooallergy.com. Archived from the original on 2015-10-16.
  6. "NIAID Scientists Link Cases of Unexplained Anaphylaxis to Red Meat Allergy | NIH: National Institute of Allergy and Infectious Diseases".
  7. http://uvahealth.com/about/news-room/archives/asthma-allergic-diseases-center-director-thomas-platts-mills-md-phd-elected-as-a-fellow-to-the-royal-society/ [ dead link ]