UQCRC1

Last updated
UQCRC1
Protein UQCRC1 PDB 1be3.png
Identifiers
Aliases UQCRC1 , D3S3191, QCR1, UQCR1, ubiquinol-cytochrome c reductase core protein I, ubiquinol-cytochrome c reductase core protein 1, PKNPY
External IDs OMIM: 191328; MGI: 107876; HomoloGene: 2525; GeneCards: UQCRC1; OMA:UQCRC1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003365

NM_025407

RefSeq (protein)

NP_003356

NP_079683

Location (UCSC) Chr 3: 48.6 – 48.61 Mb Chr 9: 108.77 – 108.78 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Cytochrome b-c1 complex subunit 1, mitochondrial is a protein that in humans is encoded by the UQCRC1 gene. [5] [6]

Its gene product is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene, MTCYTB (mitochondrial cytochrome b) and ten nuclear genes: UQCRC1, UQCRC2, Cytochrome c1, UQCRFS1 (Rieske protein), UQCRB, "11kDa protein", UQCRH (cyt c1 Hinge protein), Rieske Protein presequence, "cyt. c1 associated protein", and Rieske-associated protein.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000010256 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025651 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hoffman GG, Lee S, Christiano AM, Chung-Honet LC, Cheng W, Katchman S, Uitto J, Greenspan DS (Nov 1993). "Complete coding sequence, intron/exon organization, and chromosomal location of the gene for the core I protein of human ubiquinol-cytochrome c reductase". J Biol Chem. 268 (28): 21113–9. doi: 10.1016/S0021-9258(19)36900-5 . PMID   8407948.
  6. "Entrez Gene: UQCRC1 ubiquinol-cytochrome c reductase core protein I".

Further reading