U.S. Route 22 (US 22) is a major west–east route and one of the original United States Numbered Highways, founded in 1926. It runs from Cincinnati, Ohio, at US 27, US 42, US 127, and US 52 to Newark, New Jersey, at US 1/9 at the Newark Airport Interchange.
U.S. Route 19 or U.S. Highway 19 (US 19) is a north–south United States Numbered Highway in the Eastern United States. Despite encroaching Interstate Highways, the route has remained a long-haul road, connecting the Gulf of Mexico with Lake Erie.
U.S. Route 35 (US 35) is a United States Highway that runs southeast-northwest for approximately 412 miles (663 km) from the western suburbs of Charleston, West Virginia to northern Indiana. Although the highway is physically southeast-northwest, it is nominally north–south. The highway's southern terminus is in Teays Valley, West Virginia, near Scott Depot, at Interstate 64 (I-64). Its northern terminus is near Michigan City, Indiana, at US 20. The West Virginia portion of the highway is mostly expressway, becoming a freeway shortly before it crosses the Ohio River into Ohio. The Ohio portion has been upgraded to a four-lane highway/freeway between the West Virginia state line and Trotwood, west of Dayton.
U.S. Route 119 (US 119) is a spur of US 19. It is a north–south route that was an original United States highway of 1926. It is Corridor G of the Appalachian Development Highway System (ADHS) east of US 23 and KY 80 in Kentucky to Interstate 64 at Charleston, West Virginia.
U.S. Route 48 (US 48), also known as the incomplete Corridor H of the Appalachian Development Highway System, extends from Interstate 79 (I-79) in Weston, West Virginia, eastward across the crest of the Allegheny Mountains to I-81 in Strasburg, Virginia. It is planned to extend 157 miles (253 km) from northwestern Virginia to central West Virginia.
In the United States, Corridor D is part of the Appalachian Development Highway System. In Ohio, it follows State Route 32 from the eastern Cincinnati suburbs until a point west of Albany, where it becomes concurrent with U.S. Route 50. After crossing into West Virginia, it follows U.S. Route 50 until the Interstate 79 interchange in Clarksburg.
State Route 833 (SR 833) is a 5.10-mile (8.21 km) long east–west state highway in the southern portion of the U.S. state of Ohio. Its western terminus is at the West Virginia state line in Pomeroy, where it provides a connection to West Virginia Route 62 (WV 62) via the Pomeroy-Mason Bridge across the Ohio River. Its eastern terminus is at an interchange with U.S. Route 33, SR 7, and SR 124 approximately 2 miles (3.2 km) north of Pomeroy.
State Route 7 (SR 7), formerly known as Inter-county Highway 7 until 1921 and State Highway 7 in 1922, is a north–south state highway in the southern and eastern portions of the U.S. state of Ohio. At about 336 miles (541 km) in length, it is the longest state route in Ohio. Its southern terminus is an interchange with U.S. Route 52 (US 52) just west of Chesapeake. Its northern terminus also serves as the eastern terminus of SR 531 in Conneaut. The path of SR 7 stays within five miles (8.0 km) of the Ohio River for the southern portion, with the river being visible from much of the route. The road also remains within 10 miles (16 km) of the Pennsylvania state line for the northern portion.
West Virginia Route 9 (WV 9) is a major east–west state highway located in the eastern extents of West Virginia's Eastern Panhandle. The western terminus of the route is at the Maryland state line on the north edge of Paw Paw, where WV 9 becomes Maryland Route 51 (MD 51) upon crossing the Potomac River. The eastern terminus is at the Virginia state line at Keyes Gap near Mannings, West Virginia, where WV 9 continues onward as Virginia State Route 9 (SR 9).
U.S. Route 30 (US 30) is a U.S. Highway that runs east–west across the southern part of Pennsylvania, passing through Pittsburgh and Philadelphia on its way from the West Virginia state line east to the Benjamin Franklin Bridge over the Delaware River into New Jersey.
U.S. Route 52 (US 52) skirts the western fringes of the U.S. state of West Virginia. It runs from the Virginia state line near Bluefield, where it is concurrent with Interstate 77 (I-77), in a general northwest and north direction to I-64 at Kenova. There it turns east, overlapping I-64 for five miles (8.0 km) before splitting off onto the West Huntington Expressway into Ohio via the West Huntington Bridge. Despite having an even number, US 52 is signed north–south in West Virginia. In some other states along its route, it is signed east-west. The West Virginia segment is signed such that US 52 north corresponds to the general westward direction of the highway, and vice versa. For a while, US 52 parallels US 23, which is on the other side of the Big Sandy River in Kentucky. This continues into Ohio, where US 52 travels on the Ohio side of the Ohio River while US 23 travels on the Kentucky side.
Interstate 77 (I-77) in the US state of West Virginia is a major north–south Interstate Highway. It extends for 187.21 miles (301.29 km) between Bluefield at the Virginia state line and Williamstown at the Ohio state line.
Interstate 64 (I-64) is an Interstate Highway in the US state of West Virginia. It travels east–west through the state for 189 miles (304 km) passing by the major towns and cities of Huntington, Charleston, Beckley, and Lewisburg.
The roads of Charleston, West Virginia, include three major interstate highways, several U.S. highways and state routes, and numerous major thoroughfares.
U.S. Route 202 is a US Highway running from New Castle, Delaware, northeast to Bangor, Maine. The route runs through the southeastern part of the U.S. state of Pennsylvania, passing through the western and northern suburbs of Philadelphia in the Delaware Valley metropolitan area. US 202 serves largely as a toll-free bypass around the city, avoiding the busy traffic and congestion on Interstate 95 (I-95). It is signed north–south and follows a general southwest–northeast direction through the state, serving West Chester, King of Prussia, Bridgeport, Norristown, Montgomeryville, Doylestown, and New Hope. US 202 enters Pennsylvania from Delaware and heads north as a divided highway, where it becomes concurrent with US 322 at an intersection with US 1 in Painters Crossing. The two routes run north and become a freeway that bypasses West Chester to the east, with US 322 splitting from US 202. US 202 continues north and east along the freeway to King of Prussia, where it reverts to an at-grade divided highway following an interchange with I-76. The route becomes a one-way pair as it passes through Bridgeport and Norristown before both directions rejoin and the road continues northeast. US 202 follows an expressway-grade parkway between Montgomeryville and Doylestown prior to bypassing Doylestown to the south along a freeway. The route continues northeast as an at-grade road to New Hope, where it turns into a freeway again before it crosses the Delaware River on the New Hope–Lambertville Toll Bridge into New Jersey.
The Weirton–Steubenville, WV–OH Metropolitan Statistical Area, also known as the Upper Ohio Valley, is a metropolitan statistical area consisting of two counties in the Northern Panhandle of West Virginia and one in Ohio, anchored by the cities of Weirton and Steubenville. As of the 2020 census, the MSA had a population of 116,903. This puts it at 334th largest in the United States. It is also included in the larger Pittsburgh–New Castle–Weirton, PA–OH–WV Combined Statistical Area.
Interstate 70 (I-70) is a portion of the Interstate Highway System that runs from near Cove Fort, Utah, at a junction with I-15 to Baltimore, Maryland. It crosses the Northern Panhandle of West Virginia through Ohio County and the city of Wheeling. This segment is the shortest of all states through which I-70 passes, crossing West Virginia for only 14.45 miles (23.26 km). The Fort Henry Bridge carries I-70 from Wheeling Island across the Ohio River and into downtown Wheeling before the freeway enters the Wheeling Tunnel. I-470, a southerly bypass of Wheeling and the lone auxiliary Interstate Highway in West Virginia, is intersected near Elm Grove. Before crossing into Pennsylvania, I-70 passes The Highlands, a major shopping center in the panhandle, and the Bear Rocks Lake Wildlife Management Area. On average, between 27,000 and 53,000 vehicles use the freeway every day.
U.S. Route 250 (US 250) is a United States Numbered Highway that runs from Sandusky, Ohio to Richmond, Virginia. Within the state of Ohio, the route runs from US 6 in Sandusky to the West Virginia border at Bridgeport.
The Market Street Bridge is a suspension bridge connecting Market Street in Steubenville, Ohio and West Virginia Route 2 in Follansbee, West Virginia over the Ohio River. As a project of the Steubenville Bridge Company, it was constructed in 1905 by the Ohio Steel Erection Company, the framework was created by the Penn Bridge Company, and the original steel was done by Jones and Laughlin Steel Company and Bethlehem Steel. The bridge spans a length of 1,794 feet (547 m) with a width of 20.7 feet (6.3 m). As of 2002, the average daily traffic was estimated around 15,000 vehicles. It was listed on the National Register of Historic Places in 2019.
West Virginia's 1st Senate district is one of 17 districts in the West Virginia Senate. It is currently represented by Republican Ryan Weld and Republican Laura Wakim Chapman. All districts in the West Virginia Senate elect two members to staggered four-year terms.
US 60 in Huntington 
US 30 in Chester 
