Interstate 78 (I-78) is an east–west Interstate Highway in the Northeastern United States, running 144 miles (232 km) from I-81 northeast of Harrisburg, Pennsylvania, through Allentown to western and northern New Jersey and terminating at the Holland Tunnel entrance to Lower Manhattan in New York City. Major metropolitan areas along its route include the Lehigh Valley in Pennsylvania, the Gateway Region in New Jersey, and the New York metropolitan area.
U.S. Route 22 is a west–east route and is one of the original United States highways of 1926, running from Cincinnati, Ohio, at US 27, US 42, US 127, and US 52 to Newark, New Jersey, at U.S. Route 1/9 in the Newark Airport Interchange.
U.S. Route 222 is a U.S. Highway that is a spur of US 22 in the states of Maryland and Pennsylvania. It runs for 95 miles (153 km) from US 1 in Conowingo, Maryland, north to Interstate 78 (I-78)/Pennsylvania Route 309 in Dorneyville, Pennsylvania. US 222 is almost entirely in Pennsylvania, and serves as the state's principal artery between the Lancaster and Reading areas and the Lehigh Valley.
Pennsylvania Route 100 is a 59.4-mile (95.6 km) long state highway in the U.S. state of Pennsylvania that runs from U.S. Route 202 near West Chester north to PA 309 in Pleasant Corners. The route runs between the western suburbs of Philadelphia and the Lehigh Valley region of the state, serving Chester, Montgomery, Berks, and Lehigh counties. PA 100 intersects several important highways, including US 30 in Exton, the Pennsylvania Turnpike (Interstate 76, near Lionville, US 422 near Pottstown, US 222 in Trexlertown, and I-78/US 22 in Fogelsville. Several sections of PA 100 are multi-lane divided highway with some interchanges, including between US 202 and the Pennsylvania Turnpike in Chester County between south of Pottstown and New Berlinville, and between Trexlertown and Fogelsville.
Pennsylvania Route 309 is a state highway that runs for 134 miles (216 km) through eastern Pennsylvania. The route runs from an interchange between PA 611 and Cheltenham Avenue on the border of Philadelphia and Cheltenham Township north to an intersection with PA 29 in Bowman Creek, a village in Monroe Township in Wyoming County. The highway connects Philadelphia and its northern suburbs to Allentown and the Lehigh Valley, and Hazleton and Wilkes-Barre in the Wyoming Valley.
U.S. Route 422 (US 422) is a 271-mile (436 km) long spur route of US 22 split into two segments in the U.S. states of Ohio and Pennsylvania. The western segment of US 422 runs from downtown Cleveland, Ohio, east to Ebensburg, Pennsylvania. The eastern segment, located entirely within Pennsylvania, runs from Hershey east to King of Prussia, near Philadelphia. US 422 Business serves as a business route into each of four towns along the way.
U.S. Route 30 (US 30) is a U.S. Highway that runs east–west across the southern part of Pennsylvania, passing through Pittsburgh and Philadelphia on its way from the West Virginia state line east to the Benjamin Franklin Bridge over the Delaware River into New Jersey.
Pennsylvania Route 222 is a 4.482 mi (7.213 km)-long state highway located in Allentown and its immediate suburbs in the Lehigh Valley region in eastern Pennsylvania.
Bethlehem Pike is a historic 42.21 mi (67.93 km) long road in the U.S. state of Pennsylvania that connects Philadelphia and Bethlehem, Pennsylvania. It began as a Native American path called the Minsi Trail which developed into a colonial highway called the King's Road in the 1760s. Most of the route later became part of U.S. Route 309, now Pennsylvania Route 309.
Pennsylvania Route 378 (PA 378) is a north-to-south road in Lehigh and Northampton counties in the Lehigh Valley region of the U.S. state of Pennsylvania. The southern terminus is at PA 309 in Center Valley. Its northern terminus is at U.S. Route 22 (US 22) in Bethlehem. The route heads north from PA 309 as a two-lane undivided road through Upper Saucon Township and Lower Saucon Township before crossing South Mountain into the city of Bethlehem. Here, PA 378 follows city streets through Bethlehem's South Side, intersecting the northern terminus of PA 412. The route crosses the Lehigh River and becomes a four-lane freeway that continues north to US 22. PA 378 is the only highway from US 22 to Center City Bethlehem, and a quick route for visitors traveling to the Wind Creek Bethlehem casino resort on the city's South Side.
Pennsylvania Route 73 (PA 73) is a 62.32-mile (100.29 km) long east–west state highway in southeastern Pennsylvania. It runs from PA 61 near Leesport southeast to the New Jersey state line on the Tacony–Palmyra Bridge over the Delaware River in Philadelphia, where the road continues south as New Jersey Route 73. The route passes through rural areas of Berks County, crossing U.S. Route 222 (US 222) in Maiden Creek before heading southeast through Oley and Boyertown. PA 73 continues into Montgomery County and intersects PA 100 in Gilbertsville and PA 29 in Schwenksville before it heads into the northwest suburbs of Philadelphia. The route passes through Skippack and intersects US 202 in Center Square, PA 309 in Springfield Township, and PA 611 near Jenkintown. PA 73 continues through Northeast Philadelphia on Cottman Avenue, crossing US 1 and US 13 before coming to an interchange with Interstate 95 (I-95) near the Tacony–Palmyra Bridge.
Pennsylvania Route 12 (PA 12) is a 9.566-mile-long (15.395 km) state highway located in Berks County in eastern Pennsylvania. The western terminus of the route is at U.S. Route 222 (US 222) and US 422 in Wyomissing. Its eastern terminus is PA 662 in the community of Pricetown in Ruscombmanor Township. In the Reading area, PA 12 is a four-lane freeway called the Warren Street Bypass that heads northeast through urban areas, coming to interchanges with multiple roads including PA 183, PA 61, and US 222 Business (US 222 Bus.). In Alsace Township, the route becomes a two-lane undivided road with at-grade intersections called Pricetown Road and continues northeast through rural areas, intersecting PA 73 before ending at PA 662.
U.S. Route 22 is an east–west U.S. highway that stretches from Cincinnati, Ohio, in the west, to Newark, New Jersey, in the east. In Pennsylvania, the route runs for 338.20 miles (544.28 km) between the West Virginia state line in Washington County, where it is a freeway through the western suburbs of Pittsburgh, east to the Pennsylvania-New Jersey state line in the Lehigh Valley at Easton in the east.
U.S. Route 222 Business is a 12.17-mile (19.59 km) business route of US 222 located in Reading, Pennsylvania. The southern terminus is at US 222 in Cumru Township. Its northern terminus is at US 222 in Ontelaunee Township. The route begins at the US 222 freeway and heads through the southwestern suburbs of Reading as Lancaster Avenue, intersecting Pennsylvania Route 724 in Shillington. US 222 Bus. continues into Reading on Lancaster Avenue and intersects the northern termini of PA 625 and PA 10 before reaching an interchange with the US 422 freeway. The business route crosses the Schuylkill River and becomes Bingaman Street. US 222 Bus. turns north on 5th Street and intersects US 422 Bus. in downtown Reading and the southern terminus of PA 61 to the north of downtown. The route interchanges with the PA 12 freeway and continues north through suburban Muhlenberg Township as 5th Street Highway. US 222 Bus. reaches Temple and continues northeast to its northern terminus as Allentown Pike. US 222 Bus. is the only auxiliary route of US 222 in Pennsylvania.
U.S. Route 422 Business is a 7.29-mile-long (11.73 km) business route of US 422 located in the Reading, Pennsylvania area. The route is one of four auxiliary routes of US 422 in Pennsylvania. Its western terminus is at an interchange with US 222 and US 422 in Wyomissing. Its eastern terminus is at an interchange with US 422 in Reiffton. US 422 Bus. heads east from US 222/US 422 along Penn Avenue, passing through Wyomissing and West Reading. The route has an interchange with the US 422 freeway before it crosses the Schuylkill River into Reading. US 422 Bus. passes through downtown Reading on the one-way pair of Franklin Street eastbound and Washington Street westbound, intersecting the southern terminus of Pennsylvania Route 183 and crossing US 222 Bus. The business route heads into the eastern part of the city southeast on Perkiomen Avenue before following the one-way pair of Perkiomen Avenue eastbound and Mineral Spring Road westbound into Mount Penn. US 422 Bus. continues along Perkiomen Avenue to St. Lawrence, where it intersects the western terminus of PA 562 and turns southeast. The route passes through Reiffton before it merges into eastbound US 422.
State Route 1002(SR 1002), locally known as Tilghman Street and Union Boulevard, is a major 13.8 mi (22.2 km) long east–west road in the Lehigh Valley area of the U.S. state of Pennsylvania. The majority of the roadway is the former alignment of U.S. Route 22, maintained by the Pennsylvania Department of Transportation as a Quadrant Route, and is not signed except on small white segment markers.
Interstate 78 (I-78) is an east–west Interstate Highway stretching from Union Township, Lebanon County, Pennsylvania, in the west to the Holland Tunnel and New York City in the east. In Pennsylvania, I-78 runs for about 78 miles (126 km) from the western terminus at I-81 in Union Township east to the New Jersey state line near Easton in Northampton County.
U.S. Route 11 (US 11) roughly parallels Interstate 81 (I-81) in the U.S. state of Pennsylvania. The route runs from the Maryland state line in Antrim Township, Franklin County, northeast to the New York state line in Great Bend Township, Susquehanna County. US 11 serves Harrisburg, Wilkes-Barre, and Scranton. Between Harrisburg and Scranton, US 11 follows the Susquehanna River, while I-81 follows a shorter route over the mountains further to the east.
At least eight special routes of U.S. Route 22 have existed and at least six have been deleted.
At least four special routes of U.S. Route 422 currently exist and at least three have been decommissioned.
