XPO6 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | XPO6 , EXP6, RANBP20, exportin 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 608411 MGI: 2429950 HomoloGene: 12544 GeneCards: XPO6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Exportin-6 is a protein that in humans is encoded by the XPO6 gene. [5] [6]
Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of Ran-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled. [6]
Ran-specific binding protein 1 is an enzyme that in humans is encoded by the RANBP1 gene.
Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the nucleus of eukaryotic cells.
Mortality factor 4-like protein 2 is a protein that in humans is encoded by the MORF4L2 gene.
PHD finger protein 3 is a protein that in humans is encoded by the PHF3 gene.
Leucine-rich repeat serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the LRRK1 gene.
Hypermethylated in cancer 2 protein is a protein that in humans is encoded by the HIC2 gene.
SLIT-ROBO Rho GTPase-activating protein 3 is an enzyme that in humans is encoded by the SRGAP3 gene.
Hermansky–Pudlak syndrome 5 protein is a protein that in humans is encoded by the HPS5 gene.
Rab3 GTPase-activating protein non-catalytic subunit is an enzyme that in humans is encoded by the RAB3GAP2 gene.
Methyltransferase-like protein 13 is an enzyme that in humans is encoded by the METTL13 gene.
Exportin-4 is a protein that in humans is encoded by the XPO4 gene.
FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene.
KIAA0196 is a human gene. The product is a protein that is a component of the WASH complex, which regulates actin assembly on intracellular vesicles. Mutations in KIAA0196 are implicated in some forms of hereditary spastic paraplegia.
Regulation of nuclear pre-mRNA domain-containing protein 2 is a protein that in humans is encoded by the RPRD2 gene.
KIAA1166 is a human gene.
KIAA1411, also known as KIAA1411, is a human gene. It has one paralog, FAM135B.
Nucleoporin 93 (Nup93) is a protein that in humans is encoded by the NUP93 gene.
Tetratricopeptide repeat protein 35 is a protein that in humans is encoded by the TTC35 gene.
rotein KIAA1219 is a protein that in humans is encoded by the RALGAPB gene.
Zinc finger and BTB domain-containing protein 40 is a protein that in humans is encoded by the ZBTB40 gene.