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Vasotocin is an oligopeptide homologous to oxytocin and vasopressin found in all non-mammalian vertebrates and possibly in mammals during the fetal stage of development. Arginine vasotocin (AVT), a hormone produced by neurosecretory cells within the posterior pituitary gland (neurohypophysis) of the brain, is a major endocrine regulator of water balance and osmotic homoeostasis and is involved in social and sexual behavior in non-mammalian vertebrates. In mammals, it appears to have biological properties similar to those of oxytocin and vasopressin. It has been found to have effects on the regulation of REM sleep. Evidence for the existence of endogenous vasotocin in mammals is limited and no mammalian gene encoding vasotocin has been confirmed.
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References
- ↑ Rao VV, Löffler C, Battey J, Hansmann I (1992). "The human gene for oxytocin-neurophysin I (OXT) is physically mapped to chromosome 20p13 by in situ hybridization". Cytogenet. Cell Genet. 61 (4): 271–3. doi:10.1159/000133420. PMID 1486803.
- ↑ Wilkins; Evans (1972). "Demonstration of neurophysin in the hypothalamo-neurohypophysial system of the normal and dehydrated rat by the use of cross-species reactive anti-neurophysins". Zeitschrift für Zellforschung und mikroskopische Anatomie. 131 (2): 149–170. doi:10.1007/BF00306924. PMID 5074132. S2CID 22393640.