| 2010 Brazil Open Series | |
|---|---|
| Date | April 19 – April 25 |
| Edition | 2nd |
| Location | Curitiba, Brazil |
| Champions | |
| Singles | |
 Dominik Meffert | |
| Doubles | |
Dominik Meffert /  Leonardo Tavares | |
The 2010 Brazil Open Series was a professional tennis tournament played on outdoor red clay courts. It was part of the 2010 ATP Challenger Tour. It took place in Curitiba, Brazil between 19 and 25 April 2010.
| Nationality | Player | Ranking* | Seeding |
|---|---|---|---|
 CHI | Nicolás Massú | 93 | 1 |
 SLO | Blaž Kavčič | 119 | 2 |
 BRA | Ricardo Mello | 133 | 3 |
| BRA | Marcos Daniel | 136 | 4 |
| BRA | Thiago Alves | 148 | 5 |
| BRA | João Souza | 154 | 6 |
 PAR | Ramón Delgado | 165 | 7 |
| BRA | Júlio Silva | 166 | 8 |
The following players received wildcards into the singles main draw:
The following players received special exempt into the singles main draw:
The following players received entry from the qualifying draw:
Dominik Meffert def. Ricardo Mello, 6–4, 6–7(3), 6–2
Dominik Meffert / Leonardo Tavares def. Ramón Delgado / André Sá, 3–6, 6–2, [10–2]
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