| 2010 Blu-express.com Tennis Cup | |
|---|---|
| Date | 13 – 19 September |
| Edition | 4th |
| Location | Todi, Italy |
| Champions | |
| Singles | |
 Carlos Berlocq | |
| Doubles | |
 Flavio Cipolla / Alessio di Mauro | |
The 2010 Blu-express.com Tennis Cup was a professional tennis tournament played on outdoor red clay courts. It was the fourth edition of the tournament which is part of the 2010 ATP Challenger Tour. It took place in Todi, Italy between 13 and 19 September 2010.
| Nationality | Player | Ranking* | Seeding |
|---|---|---|---|
 ESP | Marcel Granollers | 94 | 1 |
| ARG | Carlos Berlocq | 101 | 2 |
| ITA | Paolo Lorenzi | 103 | 3 |
| ESP | Óscar Hernández | 159 | 4 |
| ARG | Diego Junqueira | 187 | 5 |
| ARG | Máximo González | 191 | 6 |
 MAR | Reda El Amrani | 198 | 7 |
 FRA | Guillaume Rufin | 206 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Gerard Granollers-Pujol (as a lucky loser) Patricio Heras
Borut Puc Janez Semrajc Walter Trusendi 
Mikhail Vasiliev (as a lucky loser) Carlos Berlocq def. Marcel Granollers, 6–4, 6–3
Flavio Cipolla / Alessio di Mauro def. Marcel Granollers / Gerard Granollers-Pujol, 6–1, 6–4
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