| 2010 Tunis Open | |
|---|---|
| Date | April 26 – May 2, 2010 |
| Edition | 6th |
| Location | Tunis, Tunisia |
| Champions | |
| Singles | |
 José Acasuso | |
| Doubles | |
 Jeff Coetzee /  Kristof Vliegen | |
The 2010 Tunis Open was a professional tennis tournament played on red clay courts. It was part of the Tretorn SERIE+ of the 2010 ATP Challenger Tour. It took place in Tunis, Tunisia between April 26 and May 2, 2010.
| Nationality | Player | Ranking* | Seeding |
|---|---|---|---|
 FRA | Florent Serra | 62 | 1 |
| FRA | Arnaud Clément | 75 | 2 |
 UKR | Illya Marchenko | 79 | 3 |
 GER | Daniel Brands | 87 | 4 |
 RUS | Igor Kunitsyn | 106 | 5 |
 POR | Rui Machado | 116 | 6 |
| POR | Frederico Gil | 120 | 7 |
| BEL | Christophe Rochus | 122 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
José Acasuso def. Daniel Brands, 6–3, 6–4
Jeff Coetzee / Kristof Vliegen def. 
James Cerretani / 
Adil Shamasdin, 7–6(3), 6–3
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