| 2010 Guzzini Challenger | |
|---|---|
| Date | July 19 – July 25 |
| Edition | 7th |
| Surface | Hard |
| Location | Recanati, Italy |
| Champions | |
| Singles | |
 Stéphane Bohli | |
| Doubles | |
 Jamie Delgado /  Lovro Zovko | |
The 2010 Guzzini Challenger was a professional tennis tournament played on hard courts. This was the seventh edition of the tournament which is part of the 2010 ATP Challenger Tour. It took place in Recanati, Italy between 19 July and 25 July 2010.
| Nationality | Player | Ranking* | Seeding |
|---|---|---|---|
 FRA | David Guez | 117 | 1 |
| SUI | Stéphane Bohli | 130 | 2 |
 CZE | Jan Hernych | 136 | 3 |
| FRA | Josselin Ouanna | 145 | 4 |
 NED | Igor Sijsling | 149 | 5 |
 BEL | Niels Desein | 164 | 6 |
| BEL | Ruben Bemelmans | 194 | 7 |
 ESP | Guillermo Alcaide | 212 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
George Bastl Olivier Charroin 
Laurynas Grigelis 
Francesco Piccari (as a Lucky Loser) Alexandre Renard Stéphane Bohli def. Adrian Mannarino, 6–0, 3–6, 7–6(5)
Jamie Delgado / Lovro Zovko def. Charles-Antoine Brézac / Vincent Stouff, 7–6(6), 6–1
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