| Singles | |
|---|---|
| 2021 Silicon Valley Classic | |
| Champion |  Danielle Collins |
| Runner-up |  Daria Kasatkina |
| Score | 6–3, 6–7(10–12), 6–1 |
| Draw | 28 |
| Seeds | 8 |
Zheng Saisai was the reigning champion [1] but chose not to participate.
Danielle Collins won the title, her second consecutive singles title on the WTA Tour, defeating Daria Kasatkina in the final, 6–3, 6–7(10–12), 6–1. [2]
Elise Mertens (semifinals)
Elena Rybakina (quarterfinals) Madison Keys (second round) Daria Kasatkina (final) Veronika Kudermetova (withdrew)
Petra Martić (second round) Danielle Collins (champion) Yulia Putintseva (quarterfinals) Alison Riske (second round)| Semifinals | Final | ||||||||||||
| 1 | Elise Mertens | 3 | 2 | ||||||||||
| 4 | Daria Kasatkina | 6 | 6 | ||||||||||
| 4 | Daria Kasatkina | 3 | 712 | 1 | |||||||||
| 7 | Danielle Collins | 6 | 610 | 6 | |||||||||
| Q | Ana Konjuh | 0 | 2 | ||||||||||
| 7 | Danielle Collins | 6 | 6 | ||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 1 | E Mertens | 6 | 4 | 6 | |||||||||||||||||||||||
 K Mladenovic | 6 | 6 | K Mladenovic | 2 | 6 | 4 | |||||||||||||||||||||
| Q |  N-l Han | 4 | 4 | 1 | E Mertens | 6 | 710 | ||||||||||||||||||||
 A Tomljanović | 1 | 7 | 7 | 8 | Y Putintseva | 3 | 68 | ||||||||||||||||||||
| A Anisimova | 6 | 5 | 5 | A Tomljanović | 6 | 5 | 3 | ||||||||||||||||||||
| D Vekić | 5 | 3 | 8 | Y Putintseva | 3 | 7 | 6 | ||||||||||||||||||||
| 8 | Y Putintseva | 7 | 6 | 1 | E Mertens | 3 | 2 | ||||||||||||||||||||
| 4 | D Kasatkina | 6 | 6 | ||||||||||||||||||||||||
| 4 | D Kasatkina | 3 | 7 | 6 | |||||||||||||||||||||||
| Q | E Bektas | 3 | 4 | C Garcia | 6 | 5 | 3 | ||||||||||||||||||||
| C Garcia | 6 | 6 | 4 | D Kasatkina | 6 | 3 | 6 | ||||||||||||||||||||
 M Linette | 6 | 6 | M Linette | 4 | 6 | 4 | |||||||||||||||||||||
| Q |  L Pattinama Kerkhove | 3 | 3 | M Linette | 7 | 77 | |||||||||||||||||||||
 A Sevastova | 3 | 3 | 6 | P Martić | 5 | 65 | |||||||||||||||||||||
| 6 | P Martić | 6 | 6 | ||||||||||||||||||||||||
| First round | Second round | Quarterfinals | Semifinals | ||||||||||||||||||||||||
| 9 | A Riske | 6 | 6 | ||||||||||||||||||||||||
| PR | C Vandeweghe | 3 | 4 | 9 | A Riske | 1 | 4 | ||||||||||||||||||||
 M Bouzková | 5 | 6 | 5 | Q | A Konjuh | 6 | 6 | ||||||||||||||||||||
| Q | A Konjuh | 7 | 3 | 7 | Q | A Konjuh | 3 | 6 | 6 | ||||||||||||||||||
| WC |  E Raducanu | 3 | 2 |  S Zhang | 6 | 2 | 0 | ||||||||||||||||||||
| S Zhang | 6 | 6 | S Zhang | 7 | 77 | ||||||||||||||||||||||
| 3 | M Keys | 5 | 65 | ||||||||||||||||||||||||
| Q | A Konjuh | 0 | 2 | ||||||||||||||||||||||||
| 7 | D Collins | 6 | 6 | 7 | D Collins | 6 | 6 | ||||||||||||||||||||
| S Rogers | 4 | 3 | 7 | D Collins | 3 | 6 | 6 | ||||||||||||||||||||
| C McNally | 4 | 2 | S Stephens | 6 | 4 | 3 | |||||||||||||||||||||
| S Stephens | 6 | 6 | 7 | D Collins | 77 | 77 | |||||||||||||||||||||
 D Yastremska | 3 | 6 | 4 | 2 | E Rybakina | 65 | 64 | ||||||||||||||||||||
| WC | C Liu | 6 | 4 | 6 | WC | C Liu | 6 | 0 | 2 | ||||||||||||||||||
| 2 | E Rybakina | 2 | 6 | 6 | |||||||||||||||||||||||
Anastasia Potapova (qualifying competition) Kristie Ahn (first round) Caty McNally (moved to main draw) Ana Konjuh (qualified) Arina Rodionova (first round) Lesley Pattinama Kerkhove (qualified) Valeria Savinykh (first round)
Mayo Hibi (first round)| First round | Qualifying competition | ||||||||||||
| 1 | Anastasia Potapova | 2 | 6 | 6 | |||||||||
| Danielle Lao | 6 | 0 | 2 | ||||||||||
| 1 | Anastasia Potapova | 77 | 5 | 5 | |||||||||
| 6 | Lesley Pattinama Kerkhove | 64 | 7 | 7 | |||||||||
 Carol Zhao | 2 | 2 | |||||||||||
| 6 | Lesley Pattinama Kerkhove | 6 | 6 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| 2 | Kristie Ahn | 3 | 6 | 0 | |||||||||
| Han Na-lae | 6 | 2 | 6 | ||||||||||
| Han Na-lae | 6 | 4 | 6 | ||||||||||
| WC | Ashlyn Krueger | 1 | 6 | 1 | |||||||||
| WC | Ashlyn Krueger | 6 | 77 | ||||||||||
| 7 | Valeria Savinykh | 1 | 62 | ||||||||||
| First round | Qualifying competition | ||||||||||||
| Alt | Emina Bektas | 6 | 1 | 6 | |||||||||
| Katie Volynets | 4 | 6 | 3 | ||||||||||
| Alt | Emina Bektas | 6 | 5 | 6 | |||||||||
| Ellen Perez | 4 | 7 | 4 | ||||||||||
| Ellen Perez | 6 | 62 | 7 | ||||||||||
| 8 | Mayo Hibi | 2 | 77 | 5 | |||||||||
| First round | Qualifying competition | ||||||||||||
| 4 | Ana Konjuh | 6 | 6 | ||||||||||
| Eri Hozumi | 3 | 2 | |||||||||||
| 4 | Ana Konjuh | 6 | 77 | ||||||||||
| WC | Robin Montgomery | 3 | 62 | ||||||||||
| WC | Robin Montgomery | 6 | 6 | ||||||||||
| 5 | Arina Rodionova | 4 | 0 | ||||||||||
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