3-fumarylpyruvate hydrolase

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3-Fumarylpyruvate hydrolase
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EC no. 3.7.1.20
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3-Fumarylpyruvate hydrolase (EC 3.7.1.20, nagK (gene), naaD (gene)) is an enzyme with systematic name 3-fumarylpyruvate hydrolyase. [1] [2] This enzyme catalyses the following chemical reaction

3-fumarylpyruvate + H2O fumarate + pyruvate

The enzyme is involved in bacterial degradation of 5-substituted salicylates.

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References

  1. Zhou NY, Fuenmayor SL, Williams PA (January 2001). "nag genes of Ralstonia (formerly Pseudomonas) sp. strain U2 encoding enzymes for gentisate catabolism". Journal of Bacteriology. 183 (2): 700–8. doi:10.1128/JB.183.2.700-708.2001. PMC   94927 . PMID   11133965.
  2. Qu Y, Spain JC (June 2011). "Molecular and biochemical characterization of the 5-nitroanthranilic acid degradation pathway in Bradyrhizobium sp. strain JS329". Journal of Bacteriology. 193 (12): 3057–63. doi:10.1128/JB.01188-10. PMC   3133195 . PMID   21498645.