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Albert Gjedde: [1] [2] [3] is a Danish-Canadian neuroscientist. He is Professor of Neurobiology and Pharmacology at the Faculty of Health Sciences and Center of Neuroscience at the University of Copenhagen. He is currently also Adjunct Professor of Neurology and Neurosurgery in the Department of Neurology, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada, Adjunct Professor of Radiology and Radiological Science in the Division of Nuclear Medicine, Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, Maryland, US, Adjunct Professor of Translational Neuropsychiatry Research, University of Southern Denmark, Odense, Denmark, and adjunct professor of psychiatry at Tabriz University of Medical Sciences, Tabriz, East Azerbadjan, Iran.
Born in the Copenhagen suburb of Gentofte in 1946, Albert Gjedde spent time as an undergraduate student in Berkeley, California, United States (1964–65, 1968), Stellenbosch, Cape Province, South Africa (1968), and Lexington, Kentucky, US (1969).
Albert Gjedde received his Medical Doctor (M.D). and Doctor of Science (D.Sc.) degrees from Copenhagen University in 1973 and 1983, respectively. He did postdoctoral work in the Neurology Department of the New York Hospital-Cornell Medical Center 1973-76 and held assistant and associate professorships in Medical Physiology at the University of Copenhagen 1976–1986.
As a junior investigator, Albert Gjedde worked as a visiting scientist at universities or research institutions in Lund, Sweden; Cologne, Leipzig, and Dresden, Germany; Paris, France; Szeged, Hungary; and Baltimore, Maryland, United States. In 1986 he joined the McConnell Brain Imaging Center at McGill University in Montreal where he held the post of Director between 1989 and 1994. [4]
As founder, Albert Gjedde headed the Positron Emission Tomography (PET) Center at Aarhus University Hospital in Denmark during the years 1994 to 2008, [5] and in this period he also founded the Center of Functionally Integrative Neuroscience (CFIN) in 2001 [6] and the Danish Neuroscience Center (DNC) in 2008, [7] [8] both at Aarhus University. Albert Gjedde joined the University of Copenhagen in 2008. He is Fellow of the Royal Society of Canada, the American Association for the Advancement of Science, and the American College of Neuropsychopharmacology. He is also Member of the Academy of Europe, the Daylight Academy, and the Norwegian Academy of Science and Letters.
Albert Gjedde's research focuses on the relations between neuroplasticity and neurotransmission that can be revealed by mapping radioligand binding and the neuroplastic changes of brain functions. The investigations explore the relation between energy metabolism and neurotransmission by recording the changes of energy metabolism and consciousness under pharmacological and other manipulations. He uses PET to understand the synthesis of radioligand and tracer molecules that match the neurotransmitter molecules and the behavior of these transmitters under different functional conditions of the brain, normal as well as pathological, and the spatial and temporal relations among changes of cerebral blood flow, which is commonly used as a measure of brain work, and the cerebral oxygen consumption rate, which is the precise measure of this work. Albert Gjedde's collaborations focus on experiments with volunteer subjects and patients that explore the lesions and degeneration of brain tissue in disorders such as epilepsy, ludomania, Parkinson's disease, stroke, depression, and somatizing disorders, as well as disorders related to addiction. Experiments explore the restructuring of neuronal networks that follows when sensory activity is processed by healthy subjects or volunteers suffering from inborn or acquired lesions.
In 1977, with Clifford Patlak, Albert Gjedde described the Gjedde-Patlak plot, also known as Multitime Graphical Analysis (MTGA),. [9] [10] [11] The MTGA linearizes irreversible brain uptake of tracers in a manner that enables regression estimates to be made of uptake rates.
Albert Gjedde has through his career been taken different international academic positions in funding agencies, editorial- and advisory boards, council-, and committees and learned societies. [15] Today he takes following positions.
Publications statistics by June 3, 2015 [42]
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Since 2010:
Albert Gjedde has peer-reviewed, authored or edited a number of publications including the following books and booklets [43] [44] [45] [46] [47] [48]
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