Amebiasis cutis

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Amebiasis cutis
Specialty Dermatology

Amebiasis cutis or ameobiasis cutis is a rare cutaneous condition characterized by ulcers caused by Entamoeba histolytica . [1] :421

A rare disease is any disease that affects a small percentage of the population. In some parts of the world, an orphan disease is a rare disease whose rarity means there is a lack of a market large enough to gain support and resources for discovering treatments for it, except by the government granting economically advantageous conditions to creating and selling such treatments. Orphan drugs are ones so created or sold.

<i>Entamoeba histolytica</i> anaerobic parasitic protozoan

Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 50 million people worldwide. E. histolytica infection is estimated to kill more than 55,000 people each year. Previously, it was thought that 10% of the world population was infected, but these figures predate the recognition that at least 90% of these infections were due to a second species, E. dispar. Mammals such as dogs and cats can become infected transiently, but are not thought to contribute significantly to transmission.

Contents

Diagnosis

Diagnosis of amebiasis cutis calls for high degree of clinical suspicion. This needs to be backed with demonstration of trophozoites from lesions. Unless an early diagnosis can be made such patients can suffer from significant morbidity. [2]

Management

See also

Related Research Articles

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Osteoma cutis is a cutaneous condition characterized by the presence of bone within the skin in the absence of a preexisting or associated lesion.

References

  1. James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN   0-7216-2921-0.
  2. Verma, Ghanshyam K; Sharma, Nand Lal; Shanker, Vinay; Mahajan, Vikram K; Kaushik, Rajani; Verma, Santwana; Jindal, Nidhi (February 2010). "Amoebiasis cutis: Clinical suspicion is the key to early diagnosis". Australasian Journal of Dermatology. 51 (1): 52–55. doi:10.1111/j.1440-0960.2009.00594.x. PMID   20148845.