Healthcare
Gleason began her career as an emergency room nurse. [3] She later transitioned into the healthcare technology sector,working for companies including Allscripts,which provided electronic medical records software. [3]
In 2011,Gleason co-founded CareSync,a Florida-based medical technology company,where she was the chief operating officer and chief strategy officer until its closure in 2018. [2] CareSync evolved from LifeSync Technology. [2] In 2015,the Obama administration named Gleason a Champion of Change for her work at CareSync,citing her efforts to improve healthcare coordination after her daughter was diagnosed with juvenile myositis,a rare autoimmune disorder,in 2010. [2] She has also served as vice president of research for the Cure JM Foundation,a nonprofit supporting research and awareness efforts for juvenile myositis. [2]
Government
After CareSync closed,Gleason joined the U.S. Digital Service (USDS) in October 2018,where she worked until December 2021. [2] [3] During this time,she was part of the White House Coronavirus Task Force's data team supervised by Deborah Birx,helping manage COVID-19 data streams from labs and hospitals. [2] Following her tenure at USDS,Gleason worked as chief product officer at Russell Street Ventures,an investment firm focused on healthcare companies. [4] She also worked at Main Street Health,which focuses on healthcare in rural communities. [5]
In late 2024,she rejoined USDS and was introduced as a new hire on December 30. [4] On January 20,2025,Trump issued Executive Order 14158 reorganizing USDS into the U.S. Department of Government Efficiency (DOGE). [4] Gleason continued at the agency,and on February 25,the White House identified her as its acting administrator. [6] The White House did not specify the date when she assumed that position. [3] She has worked closely with DOGE personnel Steve Davis and Brad Smith. [4] Gleason already knew Smith,the founder of both Russell Street Ventures and Main Street Health,where she had worked earlier. [6]
On March 19,2025 it was reported that Gleason has been working for another unrelated government entity,Department of Health and Human Services in addition to her role as acting administrator of DOGE. [7]
