Anoplocephala perfoliata

Last updated

Anoplocephala perfoliata
Anoplocephala perfoliata fig1.jpg
Beginning of patent period during the invasion of Anoplocephala perfoliata on a horse. Immature tapeworms (arrows) and tapeworms with gravid segments (arrow heads)
Scientific classification Red Pencil Icon.png
Kingdom: Animalia
Phylum: Platyhelminthes
Class: Cestoda
Order: Cyclophyllidea
Family: Anoplocephalidae
Genus: Anoplocephala
Species:
A. perfoliata
Binomial name
Anoplocephala perfoliata
(Goeze, 1782)

Anoplocephala perfoliata is the most common intestinal tapeworm of horses, and an agent responsible for some cases of equine colic. [1]

Contents

Description

Between 8 and 25 centimeters long, Anoplocephala perfoliata is part of the order Cyclophillidea and is one of the three tapeworm species that can infect horses. [2] This parasite is the most common intestinal tapeworm of horses in the world and is one of the top causes of equine colic. [1] Any horses that have access to pastures and grazing are likely to have an A. perfoliata tapeworm in their body and experience no symptoms. [2] The other two species which can infect horses are A. magna and Paranoplocephala mamillana . [2] A. perfoliata can be found in the intestinal tract of a horse at the ileocecal junction as well within the cecum and the ileum themselves. [2]

Life cycle

Life cycle Cyclophyllidean Life Cycle for Wikipedia Article.png
Life cycle

This parasite follows the general Cyclophillidean life cycle diagrammed in Figure 1. These parasites prefer rich, grassy areas and are not often found in arid, desert climate areas such as Arizona. This life cycle is indirect, and requires an intermediate host, typically an oribatid mite which lives on vegetation. The eggs from the adult worms are passed in the feces into the pasture which the mite then consumes. While in the mite, the eggs develop into larvae until this mite is consumed by a horse eating grass. [3]

Pathology

A light infection within a horse will likely not exhibit any symptoms of infection. [2] However, a horse with a heavy infection can experience GI issues, weakness and anemia. [2] Immunocompromised horses (ex: extremely old and extremely young) can have only a light parasite load, but experience infection symptoms associated with extreme pathology. [3] The tapeworm perforating through the intestinal wall and ulcerating the mucosal layer of the stomach at the site of attachment has also been seen with this parasite leading to the intussusception. [2] Horses that have cases of infection Anoplocephala perfoliata are at an increased risk of suffering from colic while infected and after being treated. [2] An infected horse can also suffer from peritonitis (inflammation of the peritoneum) as well as secondary infections and abscesses at the site of attachment. [2] Impaction of the intestine is also a possible symptom. [3] In rare cases, the intestinal tract itself can twist and even rupture. [3]

Diagnosis

Infection due to Anoplocephala perfoliata Anoplocephala perfoliata fig2.jpg
Infection due to Anoplocephala perfoliata

A fecal float can diagnose the presence of an infection however they may not always be present in a sample, especially if the host has a light infection. [2] Proglottids are released on an irregular basis as well therefore multiple tests may need to be in order to confirm an infection of Anoplocephala perfoliata. [2] Immunodiagnostic methods can be used, however they do not reliably distinguish between the two species of genus Anoplocephala which infect horses. [1]

Treatment

The typical Pyrantel pamoate (pyrantel salts) dose of 6.6 mg per kilogram. [2] At this dose, the treatment is anywhere between 80-87% effective. [3] Doubling this dose only increases the overall efficacy to 93-95%. [2] [3]

Praziquantel at a dose of 1 mg per kg is 89-100% effective at eliminating an infection of Anoplocephala perfoliata. [2] Ivermectin or Moxidectin in combination with Praziquantel are extremely effective against this parasite. [2]

No documentation of resistance to these treatments has been recorded yet. [3]

Invasion in the patent period on horse. All tapeworms with gravid segments Anoplocephala perfoliata fig3.jpg
Invasion in the patent period on horse. All tapeworms with gravid segments

Prevention

Horses cannot develop immunity to these parasites, so prevention is a key step in maintaining their health. [3]

Interval deworming is a common practice among horse owners to prevent heavy parasite infections from occurring and is a safe, effective way to prevent an infection in a horse. The typical drug for this is Ivermectin. [2]

Pyrantel salts can be administered every day that horses are grazing. [2] The daily dose to eliminate A. perfoliata and A. magna is about 2.65 mg per kilogram. [2]

Lastly, rather than treating every day or sporadically, horses can be dewormed right before grazing season begins and after at the end of the season in areas where horses are not out year round due to climate. [2] This seems to be the most beneficial plan of prevention for horses as it can remove any parasites left over from the winter months and then after grazing season, eliminates the parasites they may have become infected with over the summer. [2]

For young horses that are just getting weaned off mother's milk, tapeworm treatment is highly recommended to prevent infection, as when infection occurs this early in life, it can put them at a high risk for ileocecal colic. [3]

Related Research Articles

Trichuriasis Infection by the parasitic worm Trichuris trichiura (whipworm)

Trichuriasis, also known as whipworm infection, is an infection by the parasitic worm Trichuris trichiura (whipworm). If infection is only with a few worms, there are often no symptoms. In those who are infected with many worms, there may be abdominal pain, tiredness and diarrhea. The diarrhea sometimes contains blood. Infections in children may cause poor intellectual and physical development. Low red blood cell levels may occur due to loss of blood.

Ascariasis Disease caused by the parasitic roundworm Ascaris lumbricoides

Ascariasis is a disease caused by the parasitic roundworm Ascaris lumbricoides. Infections have no symptoms in more than 85% of cases, especially if the number of worms is small. Symptoms increase with the number of worms present and may include shortness of breath and fever in the beginning of the disease. These may be followed by symptoms of abdominal swelling, abdominal pain, and diarrhea. Children are most commonly affected, and in this age group the infection may also cause poor weight gain, malnutrition, and learning problems.

Mange Type of skin disease caused by parasitic mites

Mange is a type of skin disease caused by parasitic mites. Because various species of mites also infect plants, birds and reptiles, the term "mange", or colloquially "the mange", suggesting poor condition of the skin and fur due to the infection, is sometimes reserved for pathological mite-infestation of nonhuman mammals. Thus, mange includes mite-associated skin disease in domestic mammals, in livestock, and in wild mammals. Since mites belong to the arachnid subclass Acari, another term for mite infestation is acariasis.

Praziquantel

Praziquantel (PZQ), sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections in mammals, birds, amphibians, reptiles, and fish. In humans specifically, it is used to treat schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, hydatid disease, and other fluke infections. It should not be used for worm infections of the eye. It is taken by mouth.

Hymenolepiasis is infestation by one of two species of tapeworm: Hymenolepis nana or H. diminuta. Alternative names are dwarf tapeworm infection and rat tapeworm infection. The disease is a type of helminthiasis which is classified as a neglected tropical disease.

Albendazole

Albendazole, also known as albendazolum, is a medication used for the treatment of a variety of parasitic worm infestations. It is useful for giardiasis, trichuriasis, filariasis, neurocysticercosis, hydatid disease, pinworm disease, and ascariasis, among other diseases. It is taken orally.

Colic in horses is defined as abdominal pain, but it is a clinical symptom rather than a diagnosis. The term colic can encompass all forms of gastrointestinal conditions which cause pain as well as other causes of abdominal pain not involving the gastrointestinal tract. The most common forms of colic are gastrointestinal in nature and are most often related to colonic disturbance. There are a variety of different causes of colic, some of which can prove fatal without surgical intervention. Colic surgery is usually an expensive procedure as it is major abdominal surgery, often with intensive aftercare. Among domesticated horses, colic is the leading cause of premature death. The incidence of colic in the general horse population has been estimated between 4 and 10 percent over the course of the average lifespan. Clinical signs of colic generally require treatment by a veterinarian. The conditions that cause colic can become life-threatening in a short period of time.

<i>Hymenolepis nana</i> Species of flatworm

Dwarf tapeworm is a cosmopolitan species though most common in temperate zones, and is one of the most common cestodes infecting humans, especially children.

There are many aspects to horse management. Horses, ponies, mules, donkeys and other domesticated equids require attention from humans for optimal health and long life.

Diphyllobothriasis is the infection caused by tapeworms of the genus Diphyllobothrium.

<i>Strongylus vulgaris</i> Species of roundworm

Strongylus vulgaris, commonly known as the blood worm, is a common horse parasite in the phylum Nematoda. It looks like a long worm with a large biting mouth. They are usually reddish in color because of all the blood they take from the equine host. This nematode is considered to be one of the "most pathogenic" of the large strongyles subphylum and is distributed worldwide, wherever there are grassland and temperate environments.

<i>Hymenolepis</i> (tapeworm) Genus of worms

Hymenolepis is a genus of cyclophyllid tapeworms responsible for hymenolepiasis. They are parasites of humans and other mammals. The focus in this article is in Hymenolepis commonly parasitizing humans.

<i>Mansonella perstans</i>

Mansonella perstans is a filarial (arthropod-borne) nematode (roundworm), transmitted by tiny blood-sucking flies called midges. Mansonella perstans is one of two filarial nematodes that causes serous cavity filariasis in humans. The other filarial nematode is Mansonella ozzardi. M. perstans is widespread in many parts of sub-Saharan Africa, parts of Central and South America, and the Caribbean.

Cestoda Class of flatworms

Cestoda is a class of parasitic worms in the flatworm phylum (Platyhelminthes). Most of the species—and the best-known—are those in the subclass Eucestoda; they are ribbon-like worms as adults, known as tapeworms. Their bodies consist of many similar units known as proglottids—essentially packages of eggs which are regularly shed into the environment to infect other organisms. Species of the other subclass, Cestodaria, are mainly fish parasites.

<i>Ancylostoma braziliense</i> Species of worm

Ancylostoma braziliense is a species of hookworm belonging to the genus Ancylostoma. It is an intestinal parasite of domestic cats and dogs. Severe infection is often fatal to these pets, especially in puppies and kittens. The infection is particularly endemic in the southern United States. It is most often confused with the zoonotic hookworm species Ancylostoma ceylanicum because of their uncanny resemblance.

Anthelmintic Antiparasitic drugs that expel parasitic worms (helminths) from the body

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges or vermicides. Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals.

Bertielliasis is the infection of Bertiella, a cestode tapeworm parasite that primarily infects nonhuman primates, rodents and Australian marsupials. Occasionally, human infections have been documented by one of two species: Bertiella studeri, or Bertiella mucronata. Of 29 different Bertiella species, only these two can infect humans.

Moniezia expansa is commonly known as sheep tapeworm or double-pored ruminant tapeworm. It is a large tapeworm inhabiting the small intestines of ruminants such as sheep, goats and cattle. It has been reported from Peru that pigs are also infected. There is an unusual report of human infection in an Egyptian. It is characterized by unarmed scolex, presence of two sets of reproductive systems in each proglottid, and each proglottid being very short but very broad.

<i>Parascaris equorum</i> Species of roundworm

Parascaris equorum is a species of ascarid that is the equine roundworm. Amongst horse owners, the parasites are colloquially called "Ascarids". This is a host-specific helminth intestinal parasite that can infect horses, donkeys, and zebras. Horses up to six months of age are the most susceptible to infection. After this time, infection rates begin to decline and is extremely uncommon in horses over twelve months of age. It cannot infect humans or other animals. It is yellow-white in color, and females can become as large as 15 inches (38 cm) in length. Found worldwide, P. equorum is one of the most difficult equine parasites to kill, requiring larger doses of more powerful anthelmintic medications than are needed for other equine parasites.

Anoplocephala manubriata is a host-specific tapeworm, or cestode, that parasitizes African and Asian elephants. These parasites require intermediate and definitive hosts to complete its life cycle. A. manubriata causes gastrointestinal inflammation in elephants. When ingested in the elephant, the cestode is attached to the intestinal mucosae. The life cycle of A. manubriata have not been completely elucidated, however studies have shown through examining oribatid mites from a dung pile near an elephant site that an immature stage exists. The study concluded at least five species were contained at least one immature life stage of the cestode.

References

  1. 1 2 3 Bohórquez, Alejandro; Meana, Aránzazu; Luzón, Mónica (2012). "Differential diagnosis of equine cestodosis based on E/S and somatic Anoplocephala perfoliata and Anoplocephala magna antigens". Veterinary Parasitology. 190 (1–2): 87–94. doi:10.1016/j.vetpar.2012.06.001. PMID   22763349.
  2. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 "Tapeworms in Horses - Digestive System". Merck Veterinary Manual. Retrieved 2018-05-12.
  3. 1 2 3 4 5 6 7 8 9 "Tapeworms in Horses | AAEP". aaep.org. Retrieved 2018-05-12.