Anti-Jo1

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Anti-Jo1 is an anti-nuclear antibody. [1] [2]

Anti-Jo1 has been associated with inflammatory myopathies such as polymyositis, dermatomyositis and antisynthetase syndrome. [3] [4]

It has histidine-tRNA ligase as a target.

References

  1. ↑ Gutiérrez-Ramos R; Gonzalez-Díaz V; Pacheco-Tovar MG; López-Luna A; Avalos-Díaz E; Herrera-Esparza R (2008). "A dermatomyositis and scleroderma overlap syndrome with a remarkable high titer of anti-exosome antibodies" (PDF). Reumatismo. 60 (4): 296–300. doi: 10.4081/reumatismo.2008.296 . PMID   19132155.
  2. ↑ Zold E; Szodoray P; Gaal J; et al. (2008). "Vitamin D deficiency in undifferentiated connective tissue disease". Arthritis Res. Ther. 10 (5): R123. doi: 10.1186/ar2533 . PMC   2592813 . PMID   18928561.
  3. ↑ Kalenian M; Zweiman B (March 1997). "Inflammatory myopathy, bronchiolitis obliterans/organizing pneumonia, and anti-Jo-1 antibodies--an interesting association". Clinical and Diagnostic Laboratory Immunology. 4 (2): 236–40. doi:10.1128/CDLI.4.2.236-240.1997. PMC   170510 . PMID   9067664.
  4. ↑ "Antisynthetase syndrome". Orphanet. Retrieved 20 March 2019.
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