Highway 102 is an east–west state highway in Benton County, Arkansas. The highway connects two of western Benton County's population centers to Bentonville and Interstate 49 (I-49), the main north–south route in the Northwest Arkansas region.
Highway 156 is a designation for three east–west state highways in Washington County, Arkansas. The first segment was created in 1937, with two more created in 1973. All are minor state highways established to provide system connectivity and are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 103 is a designation for two north–south state highways in Arkansas. One segment begins in Clarksville in the Arkansas River Valley and runs north to the Ozark National Forest. A second route runs through a sparsely populated segment of the Ozark Mountains between the Buffalo National River and Highway 21 near the Missouri state line.
Highway 355 is a designation for three north–south state highways in Southwest Arkansas. The routes are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 28 is designation for three east–west state highways in Western Arkansas. Two segments together running from the Oklahoma state line to Ola have been established since the original 1926 Arkansas state highway numbering, with the third segment designated in 1963. All three highways are rural, two-lane roads with relatively low traffic serving a sparsely populated and forested part of Arkansas. The highways are maintained by the Arkansas Department of Transportation (ARDOT).
Highway 206 is a designation for three east–west state highways in the Ozark Mountains. Each segment was created during periods of state highway systemwide expansions ordered by the Arkansas General Assembly to add system mileage in every county, first in 1957, and again in 1973. All are low-traffic highways providing connectivity between rural communities and major highways in the area. All are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 396 is a former state highway near Burlington in Boone County. Between its designation as a state highway in 1973 and its decommissioning to the county road system in 2016, it was maintained by the Arkansas Department of Transportation (ArDOT).
Highway 141 is designation for two north–south state highways in Northeast Arkansas. The longer segment was created in 1931 and extended throughout the mid-20th century to the current alignment connecting Jonesboro and points north. The Jonesboro segment was a former city street added to the state highway system in 1973. Both are maintained by the Arkansas Department of Transportation.
Highway 308 is a designation for two east–west state highways in Northeast Arkansas. One segment runs east from AR 149 in Marked Tree to Spear Lake. A second route, of 10.94 miles (17.61 km) begins at Highway 118 at Whitton and runs east to US 61 at Frenchman's Bayou. The highway also includes a business route and spur route in Marked Tree. All four routes are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 179 is a north–south state highway in Franklin County, Arkansas. Since 1998, the state highway designation has run from a county road intersection at the unincorporated community of Greenwood to US Highway 64 (US 64) in Altus. The highway is maintained by the Arkansas Department of Transportation (ArDOT).
Highway 164 is a designation for four segments of state highway in the Arkansas River Valley. Each are low-volume local roads providing connectivity to small communities, or recreation areas near the Ozark National Forest. The first segment was created in 1945, with the remaining segments created during the late 1950s and 1960s, a period of major Arkansas Highway System expansion. A single spur route provides access to an industrial area in Clarksville. All routes are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 336 is a designation for two east–west state highways in the Arkansas Ozarks. Both are low traffic, two-lane, highways near Greers Ferry Lake. The longer segment was created in 1966, with the Higden segment created in 1972. Both current segments are maintained by the Arkansas Department of Transportation (ArDOT).
Several special routes of U.S. Route 49 exist. In order from south to north they are as follows.
Highway 190 is a designation for four state highways in Arkansas. Three are low-traffic rural highways in Grant County, with one designation along city streets in Pine Bluff. The rural segments were created in 1965 and 1966, with the Pine Bluff section created in 2000 as a renumbering of Highway 104. All segments are maintained by the Arkansas Department of Transportation (ARDOT).
Highway 291 is a north–south state highway in Grant County, Arkansas. The highway connects minor population centers in western Grant County. Established in 1963, the state highway designation was extended to Traskwood from 1965 to 1995, when it was truncated at Tull, forming the current alignment. The highway is maintained by the Arkansas Department of Transportation (ArDOT).
Highway 75 is a north–south state highway in the Arkansas Delta. The route runs from Highway 38/Highway 50 north to AR 14/AR 140/AR 149 in Marked Tree. Created during the initial 1926 Arkansas state highway numbering, Highway 75 has been shortened and extended over roughly the same alignment over its lifetime. The highway has one spur route, Highway 75 Spur in the small town of Parkin. Both highways are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 52 is a designation for three state highways in Southeast Arkansas. All segments are low volume, two-lane roadways in rural areas. The segment between Wilmot and Indian has been designated since the original 1926 Arkansas state highway numbering, with new designations created in 1966 and 1985. All segments are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 369 is a designation for three north–south state highways in Arkansas. All are maintained by the Arkansas Department of Transportation (ArDOT). One segment provides connectivity in the Ouachita Mountains, with the other two serving as short industrial access roads. The longest segment was designated in 1966 and extended thrice, with the two industrial access roads created in 1978 and 1980. All three segments are maintained by the Arkansas Department of Transportation (ArDOT).
Highway 339 is a short state highway in Woodruff County, Arkansas. The highway is maintained by the Arkansas Department of Transportation (ArDOT).
Highway 360 is an east–west state highways in Lafayette County, Arkansas. The route serves a rural area of South Arkansas. The segment was created in 1966, and extended in 1973. The highway is maintained by the Arkansas Department of Transportation (ArDOT).
SH-51 Oklahoma state line
AR 59 
AR 16 near Wedington 
