Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types, and driven by elevated levels of cholesterol in the blood. These lesions may lead to narrowing of the arterial walls due to buildup of atheromatous plaques. At onset there are usually no symptoms, but if they develop, symptoms generally begin around middle age. In severe cases, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney disorders, depending on which body part(s) the affected arteries are located in the body.
A citation is a reference to a source. More precisely, a citation is an abbreviated alphanumeric expression embedded in the body of an intellectual work that denotes an entry in the bibliographic references section of the work for the purpose of acknowledging the relevance of the works of others to the topic of discussion at the spot where the citation appears.
Microangiopathy is a disease of the microvessels, small blood vessels in the microcirculation. It can be contrasted to macroangiopathies such as atherosclerosis, where large and medium-sized arteries are primarily affected.
Open access (OA) is a set of principles and a range of practices through which nominally copyrightable publications are delivered to readers free of access charges or other barriers. With open access strictly defined, or libre open access, barriers to copying or reuse are also reduced or removed by applying an open license for copyright, which regulates post-publication uses of the work.
Deep vein thrombosis (DVT) is a type of venous thrombosis involving the formation of a blood clot in a deep vein, most commonly in the legs or pelvis. A minority of DVTs occur in the arms. Symptoms can include pain, swelling, redness, and enlarged veins in the affected area, but some DVTs have no symptoms.
A thoracic aortic aneurysm is an aortic aneurysm that presents primarily in the thorax.
Calcification is the accumulation of calcium salts in a body tissue. It normally occurs in the formation of bone, but calcium can be deposited abnormally in soft tissue, causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification. Calcification may also refer to the processes of normal mineral deposition in biological systems, such as the formation of stromatolites or mollusc shells.
Vascular disease is a class of diseases of the vessels of the circulatory system in the body, including blood vessels – the arteries and veins, and the lymphatic vessels. Vascular disease is a subgroup of cardiovascular disease. Disorders in this vast network of blood and lymph vessels can cause a range of health problems that can sometimes become severe, and fatal. Coronary heart disease for example, is the leading cause of death for men and women in the United States.
Journal of Experimental Medicine is a monthly peer-reviewed medical journal published by Rockefeller University Press that publishes research papers and commentaries on the physiological, pathological, and molecular mechanisms that encompass the host response to disease. The journal prioritizes studies on intact organisms and has made a commitment to publishing studies on human subjects. Topics covered include immunology, inflammation, infectious disease, hematopoiesis, cancer, stem cells and vascular biology. The journal has no single editor-in-chief, but thirteen academic editors.
Journal Citation Reports (JCR) is an annual publication by Clarivate. It has been integrated with the Web of Science and is accessed from the Web of Science Core Collection. It provides information about academic journals in the natural and social sciences, including impact factors. JCR was originally published as a part of the Science Citation Index. Currently, the JCR, as a distinct service, is based on citations compiled from the Science Citation Index Expanded and the Social Sciences Citation Index. As of the 2023 edition, journals from the Arts and Humanities Citation Index and the Emerging Sources Citation Index have also been included.
Clinical Science is a peer-reviewed medical journal that covers all areas of clinical investigation, with a focus on translational science and medicine. The journal is currently published biweekly by Portland Press on behalf of the Biochemical Society.
Cell Press is an all-science publisher of over 50 scientific journals across the life, physical, earth, and health sciences, both independently and in partnership with scientific societies. Cell Press was founded and is currently based in Cambridge, MA, and has offices across the United States, Europe, and Asia under its parent company Elsevier.
Denisa D. Wagner is an American scientist currently the Edwin Cohn Professor of Pediatrics at Boston Children's Hospital (BCH), Harvard Medical School. Wagner first arrived in the United States in 1975 as a refugee from Czechoslovakia. She received her PhD in Biology from the Massachusetts Institute of Technology and taught at the University of Rochester and Tufts University before joining the Harvard faculty in 1994.The Wagner Lab contributes in the fields of vascular biology, inflammation, and thrombosis. Her Lab focuses on how blood cells and endothelial cells respond to vascular injury. Also her lab has been studying NETs for more than a decade. In 2015, research from the lab shed light on healing wounds in patients with diabetes. In the same year she received the Robert P. Grant Medal, which is the highest award of the International Society on Thrombosis and Hemostasis (ISTH).
Robert Wayne Alexander was an American biologist and cardiologist known for research in the fields of atherosclerosis, hypertension, and vascular biology.
George "Rick" Stouffer is an American cardiologist who is Chief of the Division of Cardiology at the University of North Carolina Medical Center, where he is a practicing interventional cardiologist. Stouffer was awarded the Ernest and Hazel Craige Distinguished Professorship of Medicine in 2018; prior to that he was the Henry A. Foscue Distinguished Professor of Medicine. Stouffer is also co-director of the McAllister Heart Institute. He is known for his research regarding inpatient ST elevation myocardial infarctions.
Kathryn J. Moore is a Canadian-born American biomedical scientist and cell biologist. She is the Jean and David Blechman Professor of Cardiology and the founding director of the Cardiovascular Research Center at the New York University Grossman School of Medicine. Moore's research considers the pathogenesis of atherosclerosis, with a focus on the identification of novel therapeutic targets. She was elected Fellow of the National Academy of Sciences in 2021.
Elisabetta Dejana is an Italian cell biologist and an expert on regulation of vascular system development. She has published widely and is frequently cited for her work. She has received several important awards. Dejana is a full professor at the University of Milan and has also been appointed full professor at the Department of Immunology, Genetics and Pathology at Uppsala University in Sweden.
Owen McCarty is an American biomedical engineer who studies the dynamics of the vascular system in the context of cancer metastasis, cardiovascular disease, and inflammation. He is the Douglas Strain Professor and Chair of the Biomedical Engineering Department at Oregon Health & Science University (OHSU) and a fellow of the American Heart Association.
Esther Lutgens is a Dutch physician and molecular biologist who is Professor of Vascular Immunopathology at Amsterdam University Medical Centre. She studies the modulation of co-stimulatory pathways and the immune system.
David M. Smadja is a French hematologist working as a hospital practitioner in Georges Pompidou European Hospital, part of the AP-HP, and Paris Cité University. He specializes in hemostasis, thrombosis and vascular biology. Smadja has contributed to research on vascular and coagulation disorders associated to COVID-19 and long COVID during the global pandemic.
