Brevifolin

Brevifolin

Names
Preferred IUPAC name 1-(2-Hydroxy-4,6-dimethoxyphenyl)ethan-1-one
Other names 2-Hydroxy-4,6-dimethoxyacetophenone Phloroacetophenone 2,4-dimethyl ether Xanthoxylin Xanthoxyline
Identifiers
CAS Number	90-24-4  Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:10070
ChEMBL	ChEMBL450288
ChemSpider	60021
ECHA InfoCard	100.001.799
KEGG	C10726
PubChem CID	66654
UNII	Z8RSY5TZPA  Y
CompTox Dashboard (EPA)	10237981
InChI InChI=1S/C10H12O4/c1-6(11)10-8(12)4-7(13-2)5-9(10)14-3/h4-5,12H,1-3H3 Key: FBUBVLUPUDBFME-UHFFFAOYSA-N InChI=1/C10H12O4/c1-6(11)10-8(12)4-7(13-2)5-9(10)14-3/h4-5,12H,1-3H3 Key: FBUBVLUPUDBFME-UHFFFAOYAY
SMILES CC(=O)C1=C(C=C(C=C1OC)OC)O
Properties
Chemical formula	C10H12O4
Molar mass	196.202 g·mol−1
Appearance	solid
Melting point	85-88 °C [1]
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Brevifolin or xanthoxylin is a bioactive compound found in pomegranate. ^[2] The pharmacological profile of brevifolin is reported similar to ellagic acid, particularly with regards to absorption, distribution, and elimination rates. ^[3]

References

1. PubChem. "Xanthoxylin". pubchem.ncbi.nlm.nih.gov. Retrieved 2025-12-17.
2. Hussein, Sahar A.M; Barakat, Heba H; Merfort, Irmgard; Nawwar, Mahmoud A.M (1997). "Tannins from the leaves of Punica granatum". Phytochemistry. 45 (4): 819–823. doi:10.1016/S0031-9422(96)00888-6.
3. "Determination and pharmacokinetic study of brevifolin in rat after ig administration of pomegranate leaf extract". Chinese Pharmacological Bulletin. 21 (3): 369–372. 2005.